DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9522 and AT5G51950

DIOPT Version :9

Sequence 1:	NP_644677.1	Gene:	CG9522 / 32413	FlyBaseID:	FBgn0030587	Length:	616	Species:	Drosophila melanogaster
Sequence 2:	NP_200008.1	Gene:	AT5G51950 / 835270	AraportID:	AT5G51950	Length:	586	Species:	Arabidopsis thaliana

Alignment Length:	681	Identity:	164/681 - (24%)
Similarity:	229/681 - (33%)	Gaps:	253/681 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PFFSDVPQRNYDFIIVGGGAAGCTLAARLSENPNWSVFLIEAGG----------VENIVHQVPLL 95
            |.|:     .:|:||:|||.:||.|||.||:|.  ||.::|.||          :||       .
plant    41 PMFA-----RFDYIIIGGGTSGCALAATLSQNA--SVLVLERGGAPYDNPTATDIEN-------F 91

  Fly    96 AAHLQSTA-SNWG---------YNSTPQRHACRGMPDNKCALPRGKVLGGTSSINYMIYNRGNRR 150
            |..|.:|: .:|.         ||:                  |.:||||.|.:|...|.|..
plant    92 ATTLSNTSPKSWSQLFISEDGVYNT------------------RARVLGGGSVLNAGFYTRAG-- 136

  Fly   151 DFDAWAAAGNPGWSYDEV-------------LPYFLRSEHAQLQGLEHSPYHNHSGPLSVEDVRH 202
              |.:..  ...|..|||             .|..|..:.|...||
plant   137 --DEYVK--ETEWKTDEVEAAYEWVEKKVAFQPPVLGWQTAFKDGL------------------- 178

  Fly   203 RTRLAHAYIRAAQEAGHPRTDYNGESQLGVSYVQATTL-------KGRRHSA--FRAYIEPIRSR 258
                        .|||  ...|||   ....::..|.:       .|.||:|  ...|..|
plant   179 ------------LEAG--EFPYNG---FTYDHIYGTKIGGTIFDRAGHRHTAADLLEYANP---- 222

  Fly   259 RHNLHILTLARVTRVLIDAATK-----SAYGV------ELTHQGRSFKVKARKEIILSAGAFNSP 312
             .|:.:...|.|.::|.  .||     .||||      .:.|:....| .:..|:||||||..||
plant   223 -GNIVVYLHASVHKILF--TTKGRPRPKAYGVIFQDANGVLHKAELEK-NSMNEVILSAGAIGSP 283

  Fly   313 QLLMLSGIGPEDNLKAIGI-PLIKALPVGKRMFDHMCHFGPTFVTNTTGQTLFAAQLGAPVAKEF 376
            ||||||||||..:|.|.|| ||:         .||                        |:..:
plant   284 QLLMLSGIGPAAHLAAHGIKPLV---------LDH------------------------PMVGQ- 314

  Fly   377 LLGRADTFLSSIGGVETLTFIKVPSGKSPATQPDVELIQVAGSLASDDGTALAKGANFKPEIYEK 441
              |..|..:::|       ||..|      |..:|.||||.|....:.....|.|..|......:
plant   315 --GMGDNPMNAI-------FIPSP------TPVEVSLIQVVGITKFESYIEGASGVIFSYSWTRR 364

  Fly   442 MYKNL------------------TLRQQDHFSF---------------LIMH--FKPASVGRLWL 471
            .:..:                  ||..|....|               ||:.  ..|.|.|.|.|
plant   365 FFDGVLNYLNEMQTSRTTSTTSPTLSTQSITDFFNPINPLLNATTRAGLILQKIAGPISRGHLEL 429

  Fly   472 HNRNPLEWPRIDPKYFSAPSDVENLLEGIKEALRISKMPA-----------------MQAIGTRL 519
            .|.||.:.|.:...|:..|.|::..:|||...:::....|                 |.::.|.|
plant   430 RNTNPDDNPSVRFNYYQEPEDLQICVEGINTIIKVINSKAFSKFKYPDATIHGLLDLMLSVPTNL 494

  Fly   520 LDKPVPGCENY-EFASDDYWRCSIRTLSYTLHHQVATCRMGAESDPTTVVNHQLKVHGVRKLRVV 583
            ..:.:....|. :|..|..         .|:.|....|::|      .||:...:|.|:..|||:
plant   495 RPRHITSMFNLRQFCIDTV---------MTIWHYHGGCQVG------RVVDKNYRVLGIDSLRVI 544

  Fly   584 DTSIIPFPPTAHTNAAAFMIGEKAADMIRSE 614
            |.|.....|..:..|...|:|......|..|
plant   545 DGSTFLKSPGTNPQATVMMLGRYMGQRILQE 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9522	NP_644677.1	PRK02106	48..612	CDD:235000	160/670 (24%)
		NADB_Rossmann	52..>83	CDD:304358	17/30 (57%)
		NADB_Rossmann	127..348	CDD:304358	71/254 (28%)
		GMC_oxred_C	463..607	CDD:282984	39/161 (24%)
AT5G51950	NP_200008.1	PLN02785	10..576	CDD:215420	164/681 (24%)
		NADB_Rossmann	46..310	CDD:304358	98/373 (26%)
		GMC_oxred_C	421..565	CDD:282984	38/158 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D798314at2759
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		mtm950
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.860