DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9522 and CG9514

DIOPT Version :9

Sequence 1:	NP_644677.1	Gene:	CG9522 / 32413	FlyBaseID:	FBgn0030587	Length:	616	Species:	Drosophila melanogaster
Sequence 2:	NP_572981.1	Gene:	CG9514 / 32418	FlyBaseID:	FBgn0030592	Length:	726	Species:	Drosophila melanogaster

Alignment Length:	579	Identity:	228/579 - (39%)
Similarity:	331/579 - (57%)	Gaps:	6/579 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 NVPFFSDVPQRNYDFIIVGGGAAGCTLAARLSENPNWSVFLIEAGGVENIVHQVPLLAAHLQSTA 103
            |.||........|||||:|||:||..||:||||.|:|.:.|:||||.|..:..||||:.:|..:.
  Fly    83 NRPFNVQQVDLAYDFIIIGGGSAGTVLASRLSEIPHWKILLLEAGGHETEISDVPLLSLYLHKSK 147

  Fly   104 SNWGYNSTPQRHACRGMPDNKCALPRGKVLGGTSSINYMIYNRGNRRDFDAWAAAGNPGWSYDEV 168
            .:|.|.:.||..||:.|.|.:|...|||||||:|.:|.|:|.|||:||||.||..|||||||:::
  Fly   148 MDWKYRTQPQPTACQAMKDKRCCWTRGKVLGGSSVLNTMLYIRGNKRDFDQWADFGNPGWSYEDI 212

  Fly   169 LPYFLRSEHAQLQGL-EHSPYHNHSGPLSVEDVRHRTRLAHAYIRAAQEAGHPRTDYNGESQLGV 232
            ||||.:||..:...| .:..||...|..:|:|..:.|.:..|:::|.:|.|:...|.|||.|.|.
  Fly   213 LPYFRKSEDQRNPYLARNKRYHGTGGLWTVQDAPYNTPIGPAFLQAGEEMGYDIVDVNGEQQTGF 277

  Fly   233 SYVQATTLKGRRHSAFRAYIEPIRSRRHNLHILTLARVTRVLIDAATKSAYGVELTHQGRSFKVK 297
            .:.|....:|.|.|..::::.|.| .|.|||:...:.||:||.|..||.|.||:....||...|.
  Fly   278 GFYQFNMRRGSRSSTAKSFLRPAR-LRPNLHVALFSHVTKVLTDPHTKRATGVQFIRDGRLQNVY 341

  Fly   298 ARKEIILSAGAFNSPQLLMLSGIGPEDNLKAIGIPLIKALP-VGKRMFDHMCHFGPTFVTNTTGQ 361
            |.:|:||||||..||.|:||||||..:.|..:||||::.|| ||:.:.||:...|..|:.:....
  Fly   342 ATREVILSAGAIGSPHLMMLSGIGHGEELGRVGIPLVQHLPGVGQNLQDHIAVGGIAFLIDYPIS 406

  Fly   362 TLFAAQLGAPVAKEFLLGRADTFLSSIGGVETLTFIKVPSGKSPATQPDVELIQVAGSLASDDGT 426
            .:....:....|..:.:.......||| |:|.:.||......:....||:..:..:.|:.||.|:
  Fly   407 IVMKRMVNINTALRYAITEDGPLTSSI-GLEAVAFINTKYANASDDWPDMNFMMTSASVMSDGGS 470

  Fly   427 ALAKGANFKPEIYEKMYKNLTLRQQDHFSFLIMHFKPASVGRLWLHNRNPLEWPRIDPKYFSAPS 491
            .:........|.|::::..:..|  |.|....|..:|.|.|.:.|.::|||.:|.:...|.:.|.
  Fly   471 QVKTAHGLTDEFYQEVFGEVNNR--DVFGVFPMMLRPKSRGYIKLASKNPLRYPLLYHNYLTHPD 533

  Fly   492 DVENLLEGIKEALRISKMPAMQAIGTRLLDKPVPGCENYEFASDDYWRCSIRTLSYTLHHQVATC 556
            ||..|.||:|.|:.:.:..||:..|.|..:||||.|::....:||||.|.||..:.|::|...|.
  Fly   534 DVNVLREGVKAAVAMGETQAMKRFGARYWNKPVPNCKHLTLYTDDYWNCFIRQYTMTIYHMSGTA 598

  Fly   557 RMGAESDPTTVVNHQLKVHGVRKLRVVDTSIIPFPPTAHTNAAAFMIGEKAADMIRSEW 615
            :||..:||..||:.||:|:|:..|||:|.||:|.....:.:|...|||||.||||:..|
  Fly   599 KMGPPTDPWAVVDPQLRVYGIPGLRVIDASIMPAITNGNIHAPVVMIGEKGADMIKQLW 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9522	NP_644677.1	PRK02106	48..612	CDD:235000	223/565 (39%)
		NADB_Rossmann	52..>83	CDD:304358	19/30 (63%)
		NADB_Rossmann	127..348	CDD:304358	101/222 (45%)
		GMC_oxred_C	463..607	CDD:282984	58/143 (41%)
CG9514	NP_572981.1	PRK02106	95..679	CDD:235000	225/567 (40%)
		NADB_Rossmann	96..>126	CDD:304358	18/29 (62%)
		NADB_Rossmann	167..391	CDD:304358	100/224 (45%)
		GMC_oxred_C	505..648	CDD:282984	57/142 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm24368
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	1	1.100	-	-	P	PTHR11552
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
	9	8.960