Protein Alignment CG12539 and betA

DIOPT Version :10

• Sequence 1: NP_572976.1
• Gene: CG12539 / 32412
• FlyBaseID: FBgn0030586
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_414845.1
• Gene: betA / 945716
• ECOCYCID: EG10109
• Length: 556
• Species: Escherichia coli
• Alignment Length: 594
• Identity: 192/594 - (32%)
• Similarity: 273/594 - (45%)
• Gaps: 95/594 - (15%)

  Fly    58 YDFIVIGAGAAGCTLAARLSENPQVSVALIEAGGVE---NIAHLTPVVAGY-LQQTSSNWGYKSV 118
            :|:|:||||:||..||.||:|:|..||.|:||||.:   :.....|....: ||....||.|::.
E. coli     3 FDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFRTQMPAALAFPLQGKRYNWAYETE 67

  Fly   119 PQKLSCHGMNNNECALPRGKILGGTSSINYMIYNRGNRRDFDAWAAAGNPG---WSYDEVLPYFL 180
            |:..    |||......|||.|||:|.||.|.|.|||..|.|.||.  .||   |||.:.|||:.
E. coli    68 PEPF----MNNRRMECGRGKGLGGSSLINGMCYIRGNALDLDNWAQ--EPGLENWSYLDCLPYYR 126

  Fly   181 RSEHAQLQGLEQSPYHNHSGPLSVEYVR-FRSQMVDAFVEASVESGLPRT-DYNGESQLGVSYVQ 243
            :   |:.:.:.::.||...||:||...: ..:.:.:|.:||.|::|.||| |.||..|.|...:.
E. coli   127 K---AETRDMGENDYHGGDGPVSVTTSKPGVNPLFEAMIEAGVQAGYPRTDDLNGYQQEGFGPMD 188

  Fly   244 AN-TLNGRRHSAYSAYIKPVRDLRSNLQIFTFSQVTRILIDEATKSAYGVEFHYKNKAYTFK--A 305
            .. |..|||.|....|:...:. |.||.|.|.:....|:.|  .|.|.|||:...:.....:  |
E. coli   189 RTVTPQGRRASTARGYLDQAKS-RPNLTIRTHAMTDHIIFD--GKRAVGVEWLEGDSTIPTRATA 250

  Fly   306 RKEVILSAGSFNSPQLLMLSGIGPEDNLRGIGIPLIKALP-VGKRMFDHM-------CHFGPTFV 362
            .|||:|.||:..|||:|..||:|..:.|....|||:..|| ||:.:.||:       |.
E. coli   251 NKEVLLCAGAIASPQILQRSGVGNAELLAEFDIPLVHELPGVGENLQDHLEMYLQYECK------ 309

  Fly   363 TNTTGQTTFTSRVTPAELISFLLAGNP----------ATRMSSIGGVEALAFLKTQRSNLPNDWP 417
                         .|..|...|...|.          .|.:.:....||..|:   ||.....||
E. coli   310 -------------EPVSLYPALQWWNQPKIGAEWLFGGTGVGASNHFEAGGFI---RSREEFAWP 358

  Fly   418 DIELIMVTGSLASDEGTGLKLGANFKDEIYDRMYRELAQAQQDH-FTLLIMQFHPKSVGRLWLKD 481
            :|:...            |.:..|:..          :.|.::| |...:......|.|.:.:|.
E. coli   359 NIQYHF------------LPVAINYNG----------SNAVKEHGFQCHVGSMRSPSRGHVRIKS 401

  Fly   482 RNPLGWPKIDPKYFVAEEDVEYLLDGIKASLRIIEMPAMQRIGARLLKRTVPGCEGHQFASDDYW 546
            |:|...|.|...|...|:|.:...|.|:.:..|:..||:.:...|.:.   ||.|   ..:|:..
E. coli   402 RDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREIS---PGVE---CQTDEQL 460

  Fly   547 RCSIRTLSYTLHHQVATCRMGAESDPTTVVNHQLKVHGVRKLRVVDTSIIPFPPTAHTNAAAFMI 611
            ...:|..:.|..|...||:||  .|..:||:.:.:|||:..|||||.||:|...|.:.||...||
E. coli   461 DEFVRNHAETAFHPCGTCKMG--YDEMSVVDGEGRVHGLEGLRVVDASIMPQIITGNLNATTIMI 523

  Fly   612 GEKAADMIR 620
            |||.|||||
E. coli   524 GEKIADMIR 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12539	NP_572976.1	BetA	58..622	CDD:441878	192/594 (32%)
betA	NP_414845.1	PRK02106	1..555	CDD:235000	192/594 (32%)