Protein Alignment CG12539 and Eo

DIOPT Version :9

• Sequence 1: NP_572976.1
• Gene: CG12539 / 32412
• FlyBaseID: FBgn0030586
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_572986.1
• Gene: Eo / 32423
• FlyBaseID: FBgn0030597
• Length: 657
• Species: Drosophila melanogaster
• Alignment Length: 661
• Identity: 197/661 - (29%)
• Similarity: 295/661 - (44%)
• Gaps: 92/661 - (13%)

  Fly     6 ISQLFLL----LHLLIFTTVARGDVNRLVLDQLNQVGLVNLIEQATRPNVPRD---LSNYDFIVI 63
            ::|||.:    |.:.:..:||       :....:.:.|.|......:...|.|   :.:||:||:
  Fly    38 VTQLFSVDSSGLGISLMQSVA-------IALNASSLALANNTAWPLQHEPPEDRLEIESYDYIVV 95

  Fly    64 GAGAAGCTLAARLSENPQVSVALIEAGGVENIAHLTPVVAGYLQQTSSNWGY----KSVPQKLSC 124
            |||:||..:|:||||..||.|.|:|.|   .:..|...:.|.......:..|    ::||....|
  Fly    96 GAGSAGSIVASRLSELCQVKVLLLEEG---QLPPLESEIFGLTGALHHDERYMFLEEAVPNPKCC 157

  Fly   125 HGM-NNNECALPRGKILGGTSSINYMIYNRGNRRDFDAWAAAGNPGWSYDEVLPYFLRSEHAQLQ 188
            ..| :.:.|....|:::||..:||..|:..|:|.:|..|   .:.||.:.:|        |....
  Fly   158 QAMASMHGCVWWHGRMMGGGGAINGNIFIPGSRENFRRW---NSTGWDWTQV--------HKTYS 211

  Fly   189 GLEQSPYHNHSGPLSVEYVRFRSQMVDAFVEASVESGLPRTDYN--GESQLGVSYVQANTLNGRR 251
            .|:|     ...|..::..:...::.:.....|.|.|:||....  ..:..|.::....|:|.||
  Fly   212 RLQQ-----RLNPSYLQPNKLNLKLANLIYSGSAELGVPRMKQPLIAGATFGYTHHVPVTVNQRR 271

  Fly   252 HSAYSAYIKPVRD---LRSNLQIFTFSQVTRILIDEATKSAYGVEFHYKNKAYTFKARKEVILSA 313
            . |.||.:....|   .|.||::...:||.|:|::.|...|.||.:......:|.|...||||||
  Fly   272 R-ASSARLYLANDQVNRRGNLKVIRGAQVQRVLLNAAGSRATGVIYTLNGVEHTAKTLGEVILSA 335

  Fly   314 GSFNSPQLLMLSGIGPEDNLRGIGIPLIKALPVGKRMFDH-----MCHFGPTFVTNTTGQTTFTS 373
            |:.||.:||:||||||.:.|:...|...:.||||:.:.||     ...||.....|:|...| .:
  Fly   336 GTLNSAKLLLLSGIGPREELQRWNITTHQDLPVGRNLQDHGMMPLFLLFGSNCAVNSTRDPT-EN 399

  Fly   374 RVTPAELISFLLAGNPATRMSSIGGVEALAFLKTQRSNLPNDWPDIELIMVT----GSLASDEGT 434
            ...|..:..:||........|   |...:.::.:...:.....||:.::..|    ||..|....
  Fly   400 PYAPVSITQYLLDNQKGPLAS---GFYMMGYINSSSPSSSRGEPDLHVVAHTLLPKGSTGSFGYL 461

  Fly   435 GLKLGANFKDEIYDRMYRELAQAQQDHFTLLIMQ-----------FHPKSVGRLWLKDRNPLGWP 488
            |.:              .||.|||||     |:|           ..|.|.|::.|..:|.....
  Fly   462 GFR--------------PELIQAQQD-----ILQKGDLLQIMGSLLRPLSHGKVSLSSKNSADQA 507

  Fly   489 KIDPKYFVAEEDVEYLLDGIKASLRIIEMPAMQRIGARLLKRTVPGCEGHQFASDDYWRCSIRTL 553
            ||:..|..|.||.:.||..::...::.:....:|.|.||.|..:..|:.....|||||.|.||..
  Fly   508 KIENHYGEAVEDQQTLLRYVRYIQKLSKTRPFRRCGLRLWKPPLHECDTLAADSDDYWLCYIRYF 572

  Fly   554 SYTLHHQVATCRM----GAESDPT-TVVNHQLKVHGVRKLRVVDTSIIPFPPTAHTNAAAFMIGE 613
            .....|.|.||||    |.:|... .||:.:|:||||:.|||||.||:|..|..:||..|.||||
  Fly   573 YVGAWHSVGTCRMAPRKGVDSQENGGVVDERLRVHGVKGLRVVDASIMPELPAGNTNGPAMMIGE 637

  Fly   614 KAADMIRTDWE 624
            |.|.||..|.|
  Fly   638 KGAQMILDDRE 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12539	NP_572976.1	PRK02106	58..620	CDD:235000	184/596 (31%)
		NADB_Rossmann	59..>90	CDD:304358	18/30 (60%)
		NADB_Rossmann	128..355	CDD:304358	70/236 (30%)
		GMC_oxred_C	471..615	CDD:282984	58/148 (39%)
Eo	NP_572986.1	BetA	88..649	CDD:225186	187/604 (31%)
		NADB_Rossmann	185..375	CDD:304358	61/206 (30%)
		GMC_oxred_C	490..638	CDD:282984	57/147 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446482
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		mtm950
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11552
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
	10	9.900