Protein Alignment CG12539 and CG12398

DIOPT Version :9

• Sequence 1: NP_572976.1
• Gene: CG12539 / 32412
• FlyBaseID: FBgn0030586
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_572985.1
• Gene: CG12398 / 32422
• FlyBaseID: FBgn0030596
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 616
• Identity: 236/616 - (38%)
• Similarity: 340/616 - (55%)
• Gaps: 51/616 - (8%)

  Fly    30 VLDQLNQVGLVNLIEQATRPNVPRDL-SNYDFIVIGAGAAGCTLAARLSENPQVSVALIEAGGVE 93
            ::|:.::|..:::          .|| .:|||||||.|:|||.|||||||||:.||.|:||||.|
  Fly    38 IVDEQHRVRSIHI----------EDLRESYDFIVIGGGSAGCVLAARLSENPEWSVLLLEAGGDE 92

  Fly    94 NIAHLTPVVAGYLQQTSSNWGYKSVPQKLSCHGMNNNECALPRGKILGGTSSINYMIYNRGNRRD 158
            .:....|.:....|::..:|.|.:.|....|..|.:..|..||.|:|||.||||.|:|.||||||
  Fly    93 PLLIDLPQLYPVFQRSPWDWKYLTEPSDRYCLAMEDQRCFWPRAKVLGGCSSINAMMYIRGNRRD 157

  Fly   159 FDAWAAAGNPGWSYDEVLPYFLRSEHAQLQGLEQSPYHNHSGPLSVEYVRFRSQMVDAFVEASVE 223
            :|.|||.|||||:||.:|.||.:.|..::.|.|.||||.|.||:|||..||.|.::|.|:.|:.:
  Fly   158 YDQWAALGNPGWNYDNILHYFRKLEDMRVPGFEHSPYHGHGGPISVERYRFPSPLLDIFMRAAQQ 222

  Fly   224 SGL--PRTDYNGESQLGVSYVQANTLNGRRHSAYSAYIKPVRDLRSNLQIFTFSQVTRILIDEAT 286
            .|:  |..|:||.||.|.:....:..:|.|.||...||:.... |.||.|...:.|.||:||..:
  Fly   223 LGMVHPDGDFNGRSQTGFAPPHGSLRDGLRCSANKGYIRRSWQ-RPNLDIVLKAFVERIVIDPQS 286

  Fly   287 KSAYGVEFHYKNKAYTFKARKEVILSAGSFNSPQLLMLSGIGPEDNLRGIGIPLIKALP-VGKRM 350
            ..|.||.|.|....:|.:|::||||||||..||||||:||:||.|.|...|||:::.|| ||..:
  Fly   287 HRAIGVIFEYGLLKHTVRAKREVILSAGSLASPQLLMVSGVGPRDQLEPQGIPVVQHLPGVGGNL 351

  Fly   351 FDHMCHFGPTFVTNTTGQTTFTSRVTPAELI-------------SFLLAGNPATRMSSIGGVEAL 402
            .||:...|..: |..:||....|.:.| |::             ||..| .|.:        |.:
  Fly   352 QDHISTSGAIY-TFDSGQNRHLSFIVP-EMMNEQAVEDFVQGSDSFFYA-MPVS--------EVM 405

  Fly   403 AFLKTQRSNLPNDWPDIELIMVTGSLASDEGTGLKLGA-----NFKDEIYDRMYRELAQAQQDHF 462
            .|..|:..:...||||:::.|.:....:|.|...:.||     |:.:.....:|       ||.|
  Fly   406 GFFSTRYQDPRLDWPDVQIFMGSYGYGADGGMIGRRGAAITLDNYAEAFEPVLY-------QDSF 463

  Fly   463 TLLIMQFHPKSVGRLWLKDRNPLGWPKIDPKYFVAEEDVEYLLDGIKASLRIIEMPAMQRIGARL 527
            .:..:...|:|.|.|.|:..:|...|.|...|:....|:..:::|:|.:.|:.:.|.||.:.|.:
  Fly   464 VIAPLLMRPRSRGYLQLRSADPKVHPLIHANYYDDPHDMAVMVEGLKLAHRLTQTPVMQSLNATM 528

  Fly   528 LKRTVPGCEGHQFASDDYWRCSIRTLSYTLHHQVATCRMGAESDPTTVVNHQLKVHGVRKLRVVD 592
            .......|...::.||.:|.|..|..|.|::|.|.||:|...|||..||:.:|:|.|:|.|||:|
  Fly   529 NIYEWRNCPEVEYLSDAFWECLARFYSQTIYHPVGTCKMAPASDPAGVVDPRLRVRGMRGLRVID 593

  Fly   593 TSIIPFPPTAHTNAAAFMIGEKAADMIRTDW 623
            .||:|..||.:|||...|:.|:.||:|:.||
  Fly   594 ASIMPTIPTGNTNAPTLMLAERGADIIKEDW 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12539	NP_572976.1	PRK02106	58..620	CDD:235000	229/582 (39%)
		NADB_Rossmann	59..>90	CDD:304358	23/30 (77%)
		NADB_Rossmann	128..355	CDD:304358	111/229 (48%)
		GMC_oxred_C	471..615	CDD:282984	53/143 (37%)
CG12398	NP_572985.1	PRK02106	55..632	CDD:235000	232/589 (39%)
		NADB_Rossmann	58..>93	CDD:304358	26/34 (76%)
		NADB_Rossmann	129..354	CDD:304358	109/225 (48%)
		GMC_oxred_C	472..615	CDD:282984	52/142 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446480
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm24368
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	1	1.100	-	-	P	PTHR11552
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
	10	9.890