Protein Alignment CG12539 and Chdh

DIOPT Version :10

• Sequence 1: NP_572976.1
• Gene: CG12539 / 32412
• FlyBaseID: FBgn0030586
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_942026.1
• Gene: Chdh / 290551
• RGDID: 735166
• Length: 599
• Species: Rattus norvegicus
• Alignment Length: 581
• Identity: 193/581 - (33%)
• Similarity: 282/581 - (48%)
• Gaps: 67/581 - (11%)

  Fly    58 YDFIVIGAGAAGCTLAARLSENPQVSVALIEAG------GVENI---AHLTPVVAGYLQQTSSNW 113
            |.|||:|||:|||.||.||:|:|...|.|:|||      |.:.:   .|:...:...|.....||
  Rat    46 YTFIVVGAGSAGCVLANRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVANLCDDKYNW 110

  Fly   114 GYKSVPQKLSCHGMNNNECALPRGKILGGTSSINYMIYNRGNRRDFDAWAAAGNPGWSYDEVLPY 178
            .|.:..|.    |::......|||::.||:||:|.|:|.||:..|::.|...|..||.|...|||
  Rat   111 YYHTEAQP----GLDGRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHRQGAEGWDYAHCLPY 171

  Fly   179 FLRSEHAQLQGLEQSPYHNHSGPLSVEYVRFRSQMVDAFVEASVESGLPRT-DYNGESQLGVSYV 242
            |.:   ||...|..:.|....|||.|...:....:..||::|:.::|.|.| |.||..|.|..::
  Rat   172 FRK---AQKHELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGWM 233

  Fly   243 QANTLNGRRHSAYSAYIKPVRDLRSNLQIFTFSQVTRILIDEATKSAYGVEFHYKNKAYTFKARK 307
            ......|:|.|..|||::|... |.||:....:.|:|:|. |.|: |.|||:....:::.....:
  Rat   234 DMTIHQGKRWSTASAYLRPALS-RPNLRAEVQTLVSRVLF-EGTR-AVGVEYIKDGQSHKAYVSR 295

  Fly   308 EVILSAGSFNSPQLLMLSGIGPEDNLRGIGIPLIKALP-VGKRMFDHMCHFGPTFVTNT-TGQTT 370
            |||||.|:.||||||||||:|..|:|:.:|||::..|| ||:.:.||:    ..::.:. |...|
  Rat   296 EVILSGGAINSPQLLMLSGVGNADDLKKLGIPVVCHLPGVGQNLQDHL----EIYIQHACTQPIT 356

  Fly   371 FTSRVTPAELISFLL------AGNPATRMSSIGGVEALAFLKTQRSNLPNDWPDIELIMVTGSLA 429
            ..|...|...:...|      .|:.||.....||     |::: |..:|:  |||:...:. |..
  Rat   357 LHSAQKPLRKVCIGLEWLWRFTGDGATAHLETGG-----FIRS-RPGVPH--PDIQFHFLP-SQV 412

  Fly   430 SDEGTGLKLGANFKDEIYDRMYRELAQAQQDHFTLLIMQFHPKSVGRLWLKDRNPLGWPKIDPKY 494
            .|.|.                    ...||:.:.:.:......|||.|.|:..||...|.|:|.|
  Rat   413 IDHGR--------------------KPTQQEAYQVHVGTMRATSVGWLKLRSTNPQDHPMINPNY 457

  Fly   495 FVAEEDVEYLLDGIKASLRIIEMPAMQRIGARLLKRTVPGCEGHQFASDDYWRCSIRTLSYTLHH 559
            ...|.|||.....:|.:..|....|......:.|:      .|....||......:|..:.:.:|
  Rat   458 LSTETDVEDFRQCVKLTREIFAQEAFAPFRGKELQ------PGSHVQSDKEIDAFVRAKADSAYH 516

  Fly   560 QVATCRMGAESDPTTVVNHQLKVHGVRKLRVVDTSIIPFPPTAHTNAAAFMIGEKAADMIR 620
            ...||:||..||||.||:.|.:|.||..|||:|.||:|...:.:.||...||.|||||:|:
  Rat   517 PSCTCKMGQPSDPTAVVDQQTRVIGVENLRVIDASIMPSVVSGNLNAPTIMIAEKAADVIK 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12539	NP_572976.1	BetA	58..622	CDD:441878	193/581 (33%)
Chdh	NP_942026.1	PRK02106	45..591	CDD:235000	193/581 (33%)