Protein Alignment CG12539 and chdh-1

DIOPT Version :9

• Sequence 1: NP_572976.1
• Gene: CG12539 / 32412
• FlyBaseID: FBgn0030586
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_495846.1
• Gene: chdh-1 / 174390
• WormBaseID: WBGene00007917
• Length: 599
• Species: Caenorhabditis elegans
• Alignment Length: 602
• Identity: 185/602 - (30%)
• Similarity: 283/602 - (47%)
• Gaps: 90/602 - (14%)

  Fly    61 IVIGAGAAGCTLAARLSENPQVSVALIEAGGVEN----IAHLTPVVAGYLQQTSSNWGYKSVPQK 121
            |::|||:|||.||.||:|:|...|.|||||.|::    ..|:...:...|...:.||.|.:..||
 Worm    41 IIVGAGSAGCVLANRLTEDPSNRVLLIEAGPVDHKWDWRIHMPAALMYNLCSDTYNWHYHTTAQK 105

  Fly   122 LSCHGMNNNECALPRGKILGGTSSINYMIYNRGNRRDFDAWAAAGNPGWSYDEVLPYFLRSE-HA 185
                .:.|.....|||::.||:|::|.|.|.||:..|::.|...|..||:|...||||.::| ::
 Worm   106 ----NLGNRVFYWPRGRVWGGSSTLNAMCYVRGHAYDYNRWEKEGASGWNYANCLPYFKKAETYS 166

  Fly   186 QLQGLEQSPYHNHSGPLSVEYVRFRSQMVDAFVEASVESGLPRT-DYNGESQLGVSYVQANTLNG 249
            ...| ...||..::|||.|:.....:.:..|::....|..|..| |.|||.|.|:|.:.....||
 Worm   167 DATG-PNDPYRGNNGPLYVKKGDAENPLHKAWLNVGKEHPLGWTNDMNGEKQEGISTMDMTIHNG 230

  Fly   250 RRHSAYSAYIKPVRDLRSNLQIFTFSQVTRILIDEATKSAYGVEF--------------HYKNKA 300
            .|.||..||:.|:|: |.||...:....||:|.|  |..|.|:||              :.:.|.
 Worm   231 ERWSASKAYVHPIRN-RPNLITSSGITCTRVLFD--TNKAIGIEFIRKLNFVGTDSIDSYSREKI 292

  Fly   301 YTFKARKEVILSAGSFNSPQLLMLSGIGPEDNLRGIGIPLIKALP-VGKRMFDHMCHFGPTFVTN 364
            |   .:.:|||:.|:.|:||||||||:||.|:||...||::..|| ||:.:.||:    ..:|
 Worm   293 Y---CQGDVILAGGAINTPQLLMLSGVGPADHLRSHEIPIVANLPGVGQNLQDHL----EIYV-- 348

  Fly   365 TTGQTTFTSRVTPAELISFLLAGNPATRMSSIG--------GVEALAFLKT---QRSNLPNDWPD 418
               |...|..||.....|:....|    |..||        |:.|.:.|:|   .||:.....||
 Worm   349 ---QQESTQPVTLYNKSSWKFPHN----MIKIGLEWFTNRTGLGASSHLETGGFARSDDTVTHPD 406

  Fly   419 IELIMVTGSLASD---EGTGLKLGANFKDEIYDRMYRELAQAQQDHFTLLIMQFHPKSVGRLWLK 480
            |:...:..::..|   .||                    ....|.|    :.....:|.|.:.|:
 Worm   407 IQFHFLPSTVHDDGRTNGT--------------------CHGYQVH----VGPMRSQSKGYIMLQ 447

  Fly   481 DRNPLGWPKIDPKYFVAEEDVEYLLDGIKASLRIIEMPAMQRIGARLLKRTVPGCEGHQFASDDY 545
            .::|...|.|:|.|...:.|.......|:.|..:....|......   |...||.:....|..|.
 Worm   448 AKDPRRAPIINPNYMEEDSDWREFRKCIRVSRELFASKAFDEFRG---KELAPGPDCQSDADIDR 509

  Fly   546 WRCSIRTLSYTLHHQVATCRMGAESDPTTVVNHQ-LKVHGVRKLRVVDTSIIPFPPTAHTNAAAF 609
            :   ::..:.:.:|...||:||:|:|...|||.: :.|:|...|:|||.|::|...:.:.||...
 Worm   510 F---VKEKAASAYHPSCTCKMGSENDKMAVVNPETMGVYGTENLKVVDASVMPSIVSGNLNAPVI 571

  Fly   610 MIGEKAADMIRTDWELI 626
            |:.|:|||:|:...:|:
 Worm   572 MMAERAADLIKHKKQLL 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12539	NP_572976.1	PRK02106	58..620	CDD:235000	183/594 (31%)
		NADB_Rossmann	59..>90	CDD:304358	17/28 (61%)
		NADB_Rossmann	128..355	CDD:304358	90/243 (37%)
		GMC_oxred_C	471..615	CDD:282984	39/144 (27%)
chdh-1	NP_495846.1	PRK02106	41..599	CDD:235000	185/602 (31%)
		NADB_Rossmann	41..>78	CDD:304358	20/36 (56%)
		NADB_Rossmann	108..345	CDD:304358	90/247 (36%)
		GMC_oxred_C	439..577	CDD:282984	39/143 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	214	1.000	Domainoid score	I1583
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	310	1.000	Inparanoid score	I1553
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm14159
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.780