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Protein Alignment CG14411 and MTMR7

DIOPT Version :9

Sequence 1:	NP_001162756.1	Gene:	CG14411 / 32408	FlyBaseID:	FBgn0030582	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_004677.3	Gene:	MTMR7 / 9108	HGNCID:	7454	Length:	660	Species:	Homo sapiens

Alignment Length:	710	Identity:	150/710 - (21%)
Similarity:	256/710 - (36%)	Gaps:	211/710 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   194 KLEPFKQQNISGRIAALHIVCKNFRLLKFAFQQQDSKMFGASDQGKLIASALVRFAYPMRHDLSF 258
            ::...::|..:.....|.|.||||::::....|:..    ..|    :..:|:|.|.|::::..:
Human    54 QISTIEKQATTATGCPLLIRCKNFQIIQLIIPQERD----CHD----VYISLIRLARPVKYEELY 110

  Fly   259 AYA--------HREPYYSTLGASGTSMYATKNDWARELIRCGATE--WQVVS-------CASVQL 306
            .::        .||..:..:            |.:.|..|.|...  ||:..       |.|
Human   111 CFSFNPMLDKEEREQGWVLI------------DLSEEYTRMGLPNHYWQLSDVNRDYRVCDS--- 160

  Fly   307 LQNPLQAGKYTVPPHFVIPKSCSVDRFLDLSRAFCDSRAAFWVYSY---GSSAALVRLAELQPAA 368
                       .|....:|||.:....:..|:  ..||..|.|.||   .:.|::.|.::.....
Human   161 -----------YPTELYVPKSATAHIIVGSSK--FRSRRRFPVLSYYYKDNHASICRSSQPLSGF 212

  Fly   369 QQDTKSENVMLELVRKCDAGRQL--------KLLQLTDR---------------------LPSIQ 404
            ......:..||:.:||.:.|...        ||..:.:|                     :.:|.
Human   213 SARCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIH 277

  Fly   405 DVLRAYQKLRRLCTPETPEKFMLQDDKYLGLLEKTNWLFYVSLCLRYA-SEASATLRSGVTCVLQ 468
            .:..:.||:..:|..::|.   :.|  :|..||.:.||.::...:... ..|.|....|.:.::.
Human   278 VMRNSLQKMLEVCELKSPS---MSD--FLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVH 337

  Fly   469 ESNGRDLCCVISSLAQLLLDPHFRTIDGFQSLVQKEWVALEHPFQRRLGHVYPAQPAGGNAELFD 533
            .|:|.|....:.|:|.||||||:||:.||..|::|:|::..|.|..|.          ||.:...
Human   338 CSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRY----------GNLDGDP 392

  Fly   534 SEQSPVFLLFLDCVWQLLQQFPDEFEFTQTYLTTLWDSCFMPIFDTFQFDTQAQR--LKAVTDSQ 596
            .|.|||...|::|||||::|||..|||.:.:|..:....:...|..|..::|.:|  ||....:.
Human   393 KEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTY 457

  Fly   597 LVLRPVWDWGEQFSDKDKMFFSNPLYQRQRGDLGAQAAAVAHRRSLAVGSKGAHGAASGVTPSRN 661
            .:...:|        |::..:.|||:   |.|                     |....|......
Human   458 SLWAHLW--------KNRADYLNPLF---RAD---------------------HSQTQGTLHLPT 490

  Fly   662 TINPQLFATASSVPQDRYLQPAHRIFDLQVWDQCYYRWLPILDIRGGGQPQVDLYHRLLLSNIAK 726
            |                   |.:  |..:.|...|.|:      ..|.||:
Human   491 T-------------------PCN--FMYKFWSGMYNRF------EKGMQPR-------------- 514

  Fly   727 VQRCLDYQNFDDLPDAYYEFAGESRPNQHKDEKPDKEDEAEFVDGVERR-RKPTAKAATPT--SG 788
                   |:..|     |..|.:....|.::|....|:..|.:..|:.. .|..:|.:.|:  ||
Human   515 -------QSVTD-----YLMAVKEETQQLEEELEALEERLEKIQKVQLNCTKVKSKQSEPSKHSG 567

  Fly   789 LTS-----------VTGNLQLSTLSSFFPFGNPIAGD---APLQLYDILSSSSELLMETS 834
            .::           .:||::      .||..:|..||   |.:...|.|.||...|...|
Human   568 FSTSDNSIANTPQDYSGNMK------SFPSRSPSQGDEDSALILTQDNLKSSDPDLSANS 621

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.