DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14411 and mtmr7a

DIOPT Version :9

Sequence 1:	NP_001162756.1	Gene:	CG14411 / 32408	FlyBaseID:	FBgn0030582	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_001035406.1	Gene:	mtmr7a / 678558	ZFINID:	ZDB-GENE-060421-7754	Length:	655	Species:	Danio rerio

Alignment Length:	475	Identity:	113/475 - (23%)
Similarity:	198/475 - (41%)	Gaps:	119/475 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 SGRIAALHIVCKNFRLLKFAFQQQDSKMFGASDQGKLIASALVRFAYPMRHDLSFAY-------- 260
            ||....:|  ||||::::|...|:       ||...:..| |.|.:.|.:::..:.:
Zfish    66 SGYPLLIH--CKNFQVIQFIILQE-------SDLHNVYIS-LTRLSRPEKYEELYCFSFNPAVDK 120

  Fly   261 AHREPYYSTLGASGTSMYATKNDWARELIRCGATE--WQVVSCASVQLLQNPLQAGKY----TVP 319
            |.|:..:..:            |...|..|.|...  |.|          .|:.. .|    |.|
Zfish   121 AERQHSWDFI------------DLKAEYSRMGLPNKLWHV----------TPINR-DYRVCDTYP 162

  Fly   320 PHFVIPKSCSVDRFLDLSRAFCDSRAAFWVYSY---GSSAALVRLAELQPAAQQDTKSENVMLEL 381
            ....:|||.::...:..|:  ..||..|...||   .:.|.:.|.::...........:..||:.
Zfish   163 ADLFVPKSVTLPVIVGSSK--FRSRGRFPTLSYYCKENHATICRSSQPLSGFSARCLEDEQMLQA 225

  Fly   382 VRKCDAGRQL--------KLLQLTDR---------------------LPSIQDVLRAYQKLRRLC 417
            :.|.:.|.:.        ||..:.:|                     :.:|..:..:.|||..:.
Zfish   226 IMKSNPGSRFMYVVDTRPKLNAMANRAAGKGYENEDNYCNIKFQFIGIENIHVMRNSQQKLIEVS 290

  Fly   418 TPETPE--KFMLQDDKYLGLLEKTNWLFYVSLCLR---YASEASATLRSGVTCVLQESNGRDLCC 477
            ...:|.  :|:|.       ||.::||.::...:.   :.|:|.|.  .||:.::..|:|.|...
Zfish   291 ALRSPSMGEFLLG-------LENSDWLKHIRSIMEAGIFISKAVAD--EGVSVLVHCSDGWDRTS 346

  Fly   478 VISSLAQLLLDPHFRTIDGFQSLVQKEWVALEHPFQRRLGHVYPAQPAGGNAELFDSEQSPVFLL 542
            .:.|:|.:||||::|||.|...|::|:||:..|.|..|.||:      .|.|:    |.|||...
Zfish   347 QVCSVASVLLDPYYRTIKGMMVLIEKDWVSFGHKFSHRCGHL------DGEAK----EVSPVLDQ 401

  Fly   543 FLDCVWQLLQQFPDEFEFTQTYLTTLWDSCFMPIFDTFQFDTQAQ----RLKAVTDSQLVLRPVW 603
            ||:|||||:.|||..||:.:.:|.::.:..:...:..|..::|.:    |::..|.|      :|
Zfish   402 FLECVWQLMDQFPCAFEYNEKFLISIHNHVYSSHYGNFICNSQKERKDLRIREKTHS------IW 460

  Fly   604 DWGEQFSDKDKMFFSNPLYQ 623
                .:..::|:.|.|||::
Zfish   461 ----PYLMENKLDFMNPLFK 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14411	NP_001162756.1	PH-like	<114..225	CDD:302622	8/20 (40%)
		PTPc	<400..587	CDD:304379	59/191 (31%)
		3-PAP	<666..732	CDD:289355
mtmr7a	NP_001035406.1	PH-GRAM_MTMR7	1..103	CDD:270152	14/46 (30%)
mtmr7a	NP_001035406.1	Myotub-related	109..446	CDD:284109	89/380 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590765
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1089
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740