Protein Alignment CG14411 and MTMR9

DIOPT Version :10

• Sequence 1: NP_572972.1
• Gene: CG14411 / 32408
• FlyBaseID: FBgn0030582
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: NP_056273.2
• Gene: MTMR9 / 66036
• HGNCID: 14596
• Length: 549
• Species: Homo sapiens
• Alignment Length: 459
• Identity: 125/459 - (27%)
• Similarity: 200/459 - (43%)
• Gaps: 86/459 - (18%)

  Fly   205 GRIAALHIVCKNFRLLKFAFQQQDSKMFGASDQGKLIASALVRFAYPMRHDLSFAYAHREPYYST 269
            |.:..:.|.||:||:::......:..:..||....|.....:...||      |.|   .|.:..
Human    64 GSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYP------FFY---RPMFEV 119

  Fly   270 LGASGTSMYATKNDWARELIRCGATEWQVVSCASVQLLQNPLQAGKYTVPPHFVIPKSCSVDRFL 334
            : ..|...:..:.::  ||.....:||: :|..:.:....|      :.||...:|||.. |..|
Human   120 I-EDGWHSFLPEQEF--ELYSSATSEWR-LSYVNKEFAVCP------SYPPIVTVPKSID-DEAL 173

  Fly   335 DLSRAFCDSRAAFWVYS-YGSSAALVRLAELQP-------AAQQDTKSENVMLELVRKCDAG--- 388
            .....|... ..|.|.| |.....:|.:...||       ..::|.|..|..|.      ||
Human   174 RKVATFRHG-GRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLR------AGKRG 231

  Fly   389 -----RQLKLLQLT-----------------------DRLPSIQDVLRAYQKLRRLCTPETPEKF 425
                 |.|.:.|.|                       :|...:|:.|   .||...|..:|...
Human   232 YIIDTRSLNVAQQTRAKGGGFEQEAHYPQWRRIHKSIERYHILQESL---IKLVEACNDQTHNM- 292

  Fly   426 MLQDDKYLGLLEKTNWLFYVSLCLRYASEASATL-RSGVTCVLQESNGRDLCCVISSLAQLLLDP 489
                |::|..||.:|||.::...|..|..|:..: |.|.:.::..:.|.|....::||||::|:|
Human   293 ----DRWLSKLEASNWLTHIKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILEP 353

  Fly   490 HFRTIDGFQSLVQKEWVALEHPFQRRLGHVYPAQPAGGNAELFDSEQSPVFLLFLDCVWQLLQQF 554
            ..|||.||::|:::||:...||||:|.     ||.|..|.:  ...::||||||||||||:|:||
Human   354 RSRTIRGFEALIEREWLQAGHPFQQRC-----AQSAYCNTK--QKWEAPVFLLFLDCVWQILRQF 411

  Fly   555 PDEFEFTQTYLTTLWDSCFMPIFDTFQFDTQAQRLKAVTDSQLVLRPVWDWGEQFSDKDKMFFSN 619
            |..|||.:.:|..|::..:...|.||..:.:::|.|.....:.:  .:|.|..|.|:..|  |:|
Human   412 PCSFEFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTM--SLWSWVNQPSELSK--FTN 472

  Fly   620 PLYQ 623
            ||::
Human   473 PLFE 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14411	NP_572972.1	PH-like	<114..225	CDD:473070	6/19 (32%)
		PTP-MTMR10-like	343..549	CDD:350385	71/245 (29%)
MTMR9	NP_056273.2	PH-GRAM_MTMR9	1..97	CDD:275398	8/32 (25%)
		Myotub-related	121..446	CDD:461958	100/356 (28%)