Protein Alignment CG14411 and mtmr12

DIOPT Version :9

• Sequence 1: NP_001162756.1
• Gene: CG14411 / 32408
• FlyBaseID: FBgn0030582
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: XP_009299937.1
• Gene: mtmr12 / 569130
• ZFINID: ZDB-GENE-050401-1
• Length: 753
• Species: Danio rerio
• Alignment Length: 814
• Identity: 223/814 - (27%)
• Similarity: 342/814 - (42%)
• Gaps: 218/814 - (26%)

  Fly     9 GHGGAGSAGNADHHKRNTFTSYVAPLPGDLRATADTNEWCLPSDLRDVHLAKPRLLHGEQIVASA 73
            |.|||.|:       :.:|.|||.  |.:::...|..:       ::.|   |.||.||.:..||
Zfish     5 GSGGAKSS-------KPSFVSYVT--PEEIKLEKDPQK-------KEKH---PDLLPGEVVFCSA 50

  Fly    74 -PAYMYSPIDPMDSSGGSGSTLSAISSASGTPADRHHKEATFGLLSVTNFKLAFVPLHEKRNQAI 137
             |...|:..|           ||              :...||.|..|||::||:        :.
Zfish    51 NPILKYTQDD-----------LS--------------QRGVFGTLLCTNFRVAFI--------SD 82

  Fly   138 TAPLIDLYQ--ENTYLGRNEITLNNIDHIYTITELGRAASALQAARGMASHAGMSRRKKLEPFKQ 200
            .||..::.:  :|...|.|:|.|..:||||.:.:                     .::||
Zfish    83 DAPQEEMSKTFKNKLYGENDIPLMCVDHIYGVYD---------------------EKRKL----- 121

  Fly   201 QNISGRI------AALHIVCKNFRLLKFAF---QQQDSK------------------MFGAS--- 235
              |:|.:      :.:.|.||:.|:.:|..   :::|:|                  :|..|
Zfish   122 --ITGGLVKNKCPSKMIIHCKDLRVFQFCLTFSKEEDAKRIFQGIAHHCLEEKSLKCVFAFSYLR 184

  Fly   236 ----DQGKLIASALVRFAYPMRHDLSFAYAHREPYYSTLGASGTSMYATKNDWARELIRCGATEW 296
                |.||.....:.|.     ...|.....||          ..|:.:..||.:|:.|..|...
Zfish   185 STNPDHGKSSRKCITRL-----DSKSEMLRKRE----------AIMFDSPEDWTQEMKRTKAQCR 234

  Fly   297 QVVSCASVQLLQNPLQAGKYTVPPHFVIPKSCSVDRFLDLSRAFCDSRAAFWVYSYGSSAALVRL 361
            .|....:.:|.|.        :|.:||||.:.. |.|     .:.......|.:|:.|..||.:
Zfish   235 LVTENENFELSQR--------LPQYFVIPSALG-DLF-----NYQGKGLPIWCWSHHSGCALFK- 284

  Fly   362 AELQPAAQQDTKSE---NVMLELVRKCDAGRQLKLLQLTDRLPSIQDVLRAYQKLRRLCTPETPE 423
            |......|:|...:   :.|:..|.: :....:|...|::.||::||:.::|.|.::....:...
Zfish   285 ASFPSMTQEDGDFQSHLDTMITAVAR-NYLYSVKTEDLSESLPTLQDIQQSYNKFKQYFLIDNTT 348

  Fly   424 KFMLQDDKYLGLLEKTNWLFYVSLCLRYASEASATLRSGVTCVL-QESNGRDLCCVISSLAQLLL 487
            .|.|.|.|:...||.:.||..:..||:.|.|....|....|.|| .|..|.|||||||||||::|
Zfish   349 DFWLSDVKWFSSLESSGWLDIIRQCLQKAVEVVECLEKDNTNVLITEEEGTDLCCVISSLAQIML 413

  Fly   488 DPHFRTIDGFQSLVQKEWVALEHPFQRRLGHVYPAQPAGGNAELFDSE-QSPVFLLFLDCVWQLL 551
            ||::||:.||||||||||||..|.|..|..|::..          |.| .||||||||:|||||:
Zfish   414 DPYYRTLMGFQSLVQKEWVAGCHAFLDRCNHLHQK----------DKECHSPVFLLFLECVWQLV 468

  Fly   552 QQFPDEFEFTQTYLTTLWDSCFMPIFDTFQFDTQAQR---LKA---VTDSQLVLRP-VWDWGEQF 609
            ||....|:|::||||.|.||..:|||.||.|::...|   :||   :..|:.:..| ||||..||
Zfish   469 QQHSPAFQFSETYLTVLSDSVHVPIFSTFLFNSAHHRESVMKAESPIAQSRPLSCPTVWDWSVQF 533

  Fly   610 SDKDKMFFSNPLYQRQRGDLGAQAAAVAHRRSLAVGSKGAH------GAASGVTPSRN------- 661
            ..|.:.||.||||..:          |.|.|::....|..|      .:::..||::.
Zfish   534 DSKAQNFFFNPLYSEK----------VKHERTVRRPHKHKHQRQLSLPSSAFKTPTKKGFFKDET 588

  Fly   662 -----------------------TINPQLFATASSVPQDRY--LQPAHRIFDLQVWDQCYYRWLP 701
                                   ..:.:.:.:....|.|.:  |.|:.....:::|.|.|.||:|
Zfish   589 DSLKKMLRVKRISRWMGSPDSPVVASREFYESWQQRPLDYHGLLLPSLDGPSVRIWMQRYLRWIP 653

  Fly   702 ILDIRGGGQPQVDLYHRLLLSNIAKVQRCLDYQN 735
            .:.|.|||...:......|||.:..::|.|:.::
Zfish   654 EVHIMGGGSVAIMTKLMELLSQVEDLKRVLEQRD 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14411	NP_001162756.1	PH-like	<114..225	CDD:302622	28/121 (23%)
		PTPc	<400..587	CDD:304379	88/188 (47%)
		3-PAP	<666..732	CDD:289355	18/67 (27%)
mtmr12	XP_009299937.1	PH-like	21..215	CDD:302622	54/281 (19%)
		PTPc	221..501	CDD:304379	115/305 (38%)
		3-PAP	566..692	CDD:289355	21/122 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590771
Domainoid	1	1.000	161	1.000	Domainoid score	I4006
eggNOG	1	0.900	-	-		E1_KOG1089
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3404
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D279113at33208
OrthoFinder	1	1.000	-	-		FOG0003782
OrthoInspector	1	1.000	-	-		otm25183
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10807
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5728
SonicParanoid	1	1.000	-	-		X2638
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.890