DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14411 and sbf1

DIOPT Version :9

Sequence 1:	NP_001162756.1	Gene:	CG14411 / 32408	FlyBaseID:	FBgn0030582	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	XP_009298445.1	Gene:	sbf1 / 568277	ZFINID:	ZDB-GENE-040718-139	Length:	1936	Species:	Danio rerio

Alignment Length:	725	Identity:	156/725 - (21%)
Similarity:	268/725 - (36%)	Gaps:	204/725 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   157 TLNNIDHIYTITELGRAASALQAARGMASHAGMSRRKKLEPFKQQNIS----------GRI---- 207
            |::|:        :.||........|:.:.:....|.|.|||:...::          |.:
Zfish  1132 TMSNV--------VERACCRDYQRLGLGTLSNSLTRSKNEPFRISTVNRMYTVCRSYPGLLIVPQ 1188

  Fly   208 ----AALHIVCKNFRLLKF---AFQQQDSKMFGASDQGKLIASALVRF--------AYPMRHD-- 255
                :.:..:|:.:|..:|   .::...:|.......| |.|..:|.|        |.|.:.|
Zfish  1189 SIPDSTIQRICRCYRQNRFPVVCWRNSRTKAVLLRSAG-LHAKGVVGFFKSPNAPTAGPSQADST 1252

  Fly   256 -------LSFAYAHREPYYSTLG---ASG-TSMYATKNDWARELIRCGATEWQVVSCASVQLLQN 309
                   |....:....|..|.|   .|| ||.:.:.:|.:.:|.:           ..:..|..
Zfish  1253 SLEQEKYLQAIISSMPSYSETSGRNTLSGFTSSHMSTSDSSDKLRQ-----------PKIGALMK 1306

  Fly   310 PLQAGKYTVPPHFVIPKSCSVDRFLDLSRAFCDSRA-----AFWVYSYGSSAALVRLAELQP--- 366
            .:...|..||..|.........|.:.||:.....:|     ..|    ||.....||:...|
Zfish  1307 QVMGAKEDVPGTFSRGALGQRARVVSLSQPRVSVKARNSPRGKW----GSIRGSGRLSTYNPDVG 1367

  Fly   367 ---AAQQDTK-----SENVMLELVR---------------KCDAGRQLKLLQLTDRLPSIQDVLR 408
               |.::..:     ||...|...|               |.|:.:|.:::.:  .:..::.|..
Zfish  1368 NRLAGKESPQANGGPSETYFLRQQRAYLFIIGDKSQLKGGKQDSFQQWEVVPI--EVFDVRQVKN 1430

  Fly   409 AYQKLRRLCTPETPEKFMLQDDKYLGL---LEKTNWLFYVSLCLRYASEASATLRSGVTCVLQES 470
            :::||.:.|.|.:     |..|..:..   ||::.|:..:...|:.:......|.:|.:.::...
Zfish  1431 SFKKLMKACVPSS-----LSFDANMTFHRCLEESEWMNLLHRVLQVSVLVVELLDNGSSVMVSLE 1490

  Fly   471 NGRDLCCVISSLAQLLLDPHFRTIDGFQSLVQKEWVALEHPFQRRLGHVYPAQPAGGNAELFDSE 535
            :|.|:...:.||.|||.||::||||||:.||:|||::..|.|..|......:|.:|
Zfish  1491 DGWDVTTQVVSLVQLLSDPYYRTIDGFRLLVEKEWLSFGHRFSHRGAQTLASQSSG--------- 1546

  Fly   536 QSPVFLLFLDCVWQLLQQFPDEFEFTQTYLTTLWDSCFMPIFDTFQFDTQAQRL--------KAV 592
            .:||||.|||||.|:..|||.||||:|.||..|........|.||..|:..:|:        |..
Zfish  1547 FTPVFLQFLDCVHQIHLQFPMEFEFSQYYLKFLAYHYVSNRFRTFLLDSDYERIELGVLYEEKGE 1611

  Fly   593 TDSQLVLRPVWDWGEQFSDKDKMFFSNPLYQRQRGDLGAQAAAVAHRRSLAVGSKGAHGAASGVT 657
            ..|..|.:.|||:.::.:.|..:|::
Zfish  1612 RKSTQVCKSVWDYIDRLNKKTPIFYN--------------------------------------- 1637

  Fly   658 PSRNTINPQLFATASSVPQDRYLQPAHRIFDLQVWDQCYYR-----------WLPILDIRGGGQ- 710
                    .:|    |..::..|:|...:.:|:|||  :|.           |    ::..|.|
Zfish  1638 --------YMF----SPEEEEVLKPYSFVSNLKVWD--FYTEETLSEGPSFDW----ELVQGRQE 1684

  Fly   711 -PQVDLYHRLLLSNIAKVQRCLDYQNFDDL----PDAYYEFAG-----ESRPNQHKDEKPDKEDE 765
             ||.:...: ..:...|.:|.:.:..:|:|    |||..:...     |:...|..::..|..|:
Zfish  1685 KPQEEAGDK-QETTAPKSKRRIVWPCYDNLSKVVPDAITKLLQDVQNLETELGQPTEKWKDTWDK 1748

  Fly   766 AEFVDGVERR 775
            .:....||.|
Zfish  1749 IKTTQRVESR 1758

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14411	NP_001162756.1	PH-like	<114..225	CDD:302622	14/88 (16%)
		PTPc	<400..587	CDD:304379	63/189 (33%)
		3-PAP	<666..732	CDD:289355	16/78 (21%)
sbf1	XP_009298445.1	uDENN	1..86	CDD:214824
		DENN	117..327	CDD:280329
		dDENN	381..449	CDD:129037
		SBF2	560..782	CDD:289132
		PH-GRAM_MTMR5	910..1027	CDD:275417
		Myotub-related	1143..1598	CDD:284109	115/486 (24%)
		PH_Sbf1_hMTMR5	1829..1934	CDD:269941
		PH	1834..1934	CDD:278594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590799
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840