DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14411 and mtmr7b

DIOPT Version :9

Sequence 1:	NP_001162756.1	Gene:	CG14411 / 32408	FlyBaseID:	FBgn0030582	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	XP_005168409.1	Gene:	mtmr7b / 559198	ZFINID:	ZDB-GENE-050913-66	Length:	645	Species:	Danio rerio

Alignment Length:	797	Identity:	173/797 - (21%)
Similarity:	275/797 - (34%)	Gaps:	253/797 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 RHHKEATFGLLSVTNFKLAFVPLHEKRNQAITAPLIDLYQENTYLGRNEITLNNIDHIYTITELG 171
            |..::||.|.|.:::....||...|.|.:  |..|..|             ::|::.:.|
Zfish    18 RTPRKATVGTLYLSSTHTIFVENSEARKE--TWVLHSL-------------VSNVERLPT----- 62

  Fly   172 RAASALQAARGMASHAGMSRRKKLEPFKQQNISGRIAALHIVCKNFRLLKFAFQQQDSKMFGASD 236
                                          |.||  :.:.|.||||.:.:....|:       .|
Zfish    63 ------------------------------NPSG--SPVIIRCKNFIVYRLLIPQE-------KD 88

  Fly   237 QGKLIASALVRFAYPMRHDLSFAYAH--------REPYYSTLGASGTSMYATKNDWARELIRCG- 292
            ...::|| |.|.:.|.|:...|.::.        ||..:..:            |...|..|.|
Zfish    89 CLDVVAS-LTRLSRPERYGELFCFSFNPNLDKELREKAWGFM------------DLKAEFNRMGI 140

  Fly   293 -ATEWQVVSCASVQLLQNPLQAGKYTVPPHFVIPKSCSVDRFLDLSRAFCDSRAAFWVYSY---G 353
             :..|.|.:......|.:       |.|....:|||.|  ..:.:..|...||....|.||   .
Zfish   141 PSNLWHVTAANHEYRLCD-------TYPSELFVPKSAS--PAVIVGSAKFRSRGRLPVLSYFHRD 196

  Fly   354 SSAALVRLAELQPAAQQDTKSENVMLELVRKCDAGRQL--------KLLQLTDR----------- 399
            :||::.|.::........:..:..||:.:.|.:...:.        ||..:.:|
Zfish   197 TSASICRSSQPLSGFSARSSDDEQMLQAIMKSNPVSEFMYVVDTRPKLNAMANRAAGKGYENEDH 261

  Fly   400 ----------LPSIQDVLRAYQKLRRLCTPETPEKFMLQDDKYLGLLEKTNWLFYVSLCL-RYAS 453
                      :.:|..:..:.|||..:.....|.   :.|  :|..||.:.||.::...| ....
Zfish   262 YTNIKLQFIGIENIHVMRNSQQKLIDVGDMAAPS---MAD--FLWGLENSGWLKHIKAVLDAGVF 321

  Fly   454 EASATLRSGVTCVLQESNGRDLCCVISSLAQLLLDPHFRTIDGFQSLVQKEWVALEHPFQRRLGH 518
            .|.|....||:.::..|:|.|......|:|.:||||::|||.|...|::|:||:..|.|..|..|
Zfish   322 IAKAVAEDGVSVLVHCSDGWDRTAQACSVASVLLDPYYRTIKGLMVLIEKDWVSFGHKFSHRYAH 386

  Fly   519 VYPAQPAGGNAELFDSEQSPVFLLFLDCVWQLLQQFPDEFEFTQTYLTTLWDSCFMPIFDTFQFD 583
            : ...|         .|.|||...||:|||||:||||..|||.:.:|..|....:...:..|..:
Zfish   387 L-DGDP---------KEVSPVMDQFLECVWQLMQQFPCAFEFNERFLIQLHMLIYSCQYGNFIGN 441

  Fly   584 TQAQR--LKAVTDSQLVLRPVWDWGEQFSDKDKMFFSNPLYQRQRGDLGAQAAAVAHRRSLAVGS 646
            .|.:|  ||....:..:...:|:        ::..::||||:..
Zfish   442 CQKERRDLKLQERTHSLWPHLWE--------NRAEYTNPLYRTD--------------------- 477

  Fly   647 KGAHGAASGVTPSRNTINPQLFATASSVPQDRYLQPAHRIFDLQVWDQCYYRWLPILDIRGGGQP 711
               |....||                       |:|....:..:.|...|.|
Zfish   478 ---HSQTQGV-----------------------LRPLTTAYCFKFWKGMYGR------------- 503

  Fly   712 QVDLYHRLLLSNIAKVQRCL-----DYQNFDDLPDAYYEFAGESRPNQHKDEKPDKEDEAEFVDG 771
                ..|.|.|..:... ||     :.|..::...|:.|     |..|.|::|...| ..:....
Zfish   504 ----AERSLSSQQSPAD-CLNAVREESQQLEEELTAHQE-----RLAQLKEKKTSGE-RKKISRL 557

  Fly   772 VERRRKPTAKAATPTSGLTSVTGNLQLSTLSSFF--PFG--NPIAGDAPLQLY--------DILS 824
            .||.|:|     ||..|        :|.:...:|  |.|  :..:...||.|.        |.||
Zfish   558 SERARRP-----TPNEG--------ELDSPQDYFSTPRGEKHTPSFTLPLDLAAQTKNGDPDDLS 609

  Fly   825 SSSELLMETSSFLDKSS 841
            :.|:|   .|...|.||
Zfish   610 TCSDL---ESGVADLSS 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14411	NP_001162756.1	PH-like	<114..225	CDD:302622	19/110 (17%)
		PTPc	<400..587	CDD:304379	60/187 (32%)
		3-PAP	<666..732	CDD:289355	10/70 (14%)
mtmr7b	XP_005168409.1	PH-like	1..102	CDD:302622	28/143 (20%)
mtmr7b	XP_005168409.1	Myotub-related	108..445	CDD:284109	91/372 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590766
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840