back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14411 and mtmr8

DIOPT Version :9

Sequence 1:	NP_001162756.1	Gene:	CG14411 / 32408	FlyBaseID:	FBgn0030582	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_956688.1	Gene:	mtmr8 / 393365	ZFINID:	ZDB-GENE-040426-1016	Length:	632	Species:	Danio rerio

Alignment Length:	600	Identity:	142/600 - (23%)
Similarity:	244/600 - (40%)	Gaps:	132/600 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 LIDLYQE-NTYLGRNEITLNNIDHIYTITELGRAASALQAARGMASHAGMSRRKKLEPFKQQNIS 204
            |::.|.| .:.||...:|..::.::...:...:.|..|.       |..:|..|.|       ::
Zfish    14 LLNRYTEKKSALGTLYLTATHLIYVEQTSNTRKEAWVLH-------HHILSVEKLL-------LT 64

  Fly   205 GRIAALHIVCKNFRLLKFAFQQ----QDSKMFGASDQGKLIASALVRFAYPMRHDLSFAYAHREP 265
            .....|.|.||.|:.|...||:    ||            :..:|:|.:.|::.:..:|:.:...
Zfish    65 ASGCPLLIRCKTFQHLHLLFQKERDCQD------------VYQSLLRLSQPVKEEELYAFLYNPH 117

  Fly   266 YYSTLGASGTSMYATKNDWARELIRCGATE--WQV-------VSCASVQLLQNPLQAGKYTVPPH 321
            ........|..:.:..||:.    |.|.:.  |::       ..|:              |.|..
Zfish   118 QNEEERRRGWELISVVNDFN----RMGLSNDYWEISHINKNFEMCS--------------TYPAI 164

  Fly   322 FVIPKSCSVDRFLDLSRAFCDSRAAFWVYSY---GSSAALVRLAELQPAAQQDTK--SENVMLEL 381
            ..:|||.||...  ...|...||....|.||   .:.||:.|.:  ||.:..:::  .:..||:.
Zfish   165 LGLPKSASVATV--TGSAKFRSRGRLPVLSYYHKDTKAAICRCS--QPLSGLNSRCVEDEQMLQA 225

  Fly   382 VRKCDAGRQL--------KLLQLTDR---------------------LPSIQDVLRAYQKLRRLC 417
            :.:.:.....        ||..:.:|                     :.:|..:..:.|||..:|
Zfish   226 ISQANPNSPFIYVVDTRPKLNAMANRAAGKGYENEDNYSNIRFQFQGIENIHVMRSSLQKLLEVC 290

  Fly   418 TPETPEKFMLQDDKYLGLLEKTNWLFYVSLCLR---YASEASATLRSGVTCVLQESNGRDLCCVI 479
            :.::|.   :.|  ||..||.:.||.::...:.   :.::|....|:.|  ::..|:|.|....:
Zfish   291 SMKSPS---MSD--YLTGLENSGWLRHIKSVMDAGVFLAKAVCEERASV--LVHCSDGWDRTAQV 348

  Fly   480 SSLAQLLLDPHFRTIDGFQSLVQKEWVALEHPFQRRLGHVYPAQPAGGNAELFDSEQSPVFLLFL 544
            .|||.|||||::|||.|...|::|||::..|.|..|.||: .:.|         .|.||||..||
Zfish   349 CSLACLLLDPYYRTIKGLMVLIEKEWISFGHKFSHRCGHL-DSDP---------KEASPVFTQFL 403

  Fly   545 DCVWQLLQQFPDEFEFTQTYLTTLWDSCFMPIFDTFQFDTQAQRLKAVTDSQLVLRPVWDWGEQF 609
            :|||||.||||..|||.:.||..:.|..:...:..|..:.|.:||    |.:|..:....|....
Zfish   404 ECVWQLSQQFPCVFEFNEHYLIEIHDQVYACQYGNFIGNCQKERL----DMRLHEKTFSLWPHLL 464

  Fly   610 SDKDKMFFSNPLYQRQRGDLGAQAAAVAHRRSLAVGSKGAHGAAS----GVTPSRNTINPQLFAT 670
            .::.:  :.||||:|      :..:.|....:|.:..|...|..:    |:.|.::.::..|..|
Zfish   465 ENQHQ--YRNPLYRR------SLESTVLRPSTLPLHFKFWCGMYNHYDRGMHPKQSVLDTLLTLT 521

  Fly   671 ASSVPQDRYLQPAHR 685
            ...|..:|.:....|
Zfish   522 QRQVEGERTMTELQR 536

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.