Protein Alignment CG14411 and Mtm1

DIOPT Version :10

• Sequence 1: NP_572972.1
• Gene: CG14411 / 32408
• FlyBaseID: FBgn0030582
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: NP_001013065.2
• Gene: Mtm1 / 288762
• RGDID: 1304582
• Length: 603
• Species: Rattus norvegicus
• Alignment Length: 732
• Identity: 168/732 - (22%)
• Similarity: 279/732 - (38%)
• Gaps: 241/732 - (32%)

  Fly   115 GLLSVTNFKLAFVPLHEKRNQAITAPLIDLYQENTYLGRNEITLNNIDHIYTITELGRAASALQA 179
            |.|.:||::|....|     :...||::|:               .:..|..|.::|...|
  Rat    61 GRLYITNYRLYLRSL-----ETDLAPILDV---------------PLGVISRIEKMGGVTS---- 101

  Fly   180 ARGMASHAGMSRRKKLEPFKQQNISGRIAALHIVCKNFRLLKFAFQQQDSKMFGASDQGKLIASA 244
             ||..|:                      .|.|.||:.|.|:||.:|:     |.|.:.  |...
  Rat   102 -RGENSY----------------------GLDITCKDLRNLRFALKQE-----GHSRRD--IFDV 136

  Fly   245 LVRFAYPMRHDLS-FAYAHREPYYSTLGASGTSMYATKNDWARELIRCGATE--WQVVSCASVQL 306
            |.|.|:|:.::|. ||:.:.|.:    ...|.::|....::.|:    |..:  |::
  Rat   137 LTRHAFPLAYNLPLFAFVNEEKF----KVDGWAIYNPVEEYRRQ----GLPDRHWRI-------- 185

  Fly   307 LQNPLQAGKY----TVPPHFVIPKSCSVDRFLDLSRAFCDSRAAF----------WVYSYGSSAA 357
               .....:|    |.|...|:|...|.|   ||.|.     |.|          |::. .:.||
  Rat   186 ---SFVNQRYELCDTYPALLVVPYRASDD---DLRRV-----ATFRSRNRIPVLSWIHP-ENRAA 238

  Fly   358 LVRLAE-LQPAAQQDTKSENVMLELVRKCDAGRQLKLLQLTDRLPSIQDVLR-----------AY 410
            ::|.:: |.....:.::.:...|:::|  :..:|...|.:.|..|.:..|..           ||
  Rat   239 IMRCSQPLVGVGGKRSRDDERYLDIIR--ETNKQTSKLTIYDARPGVNAVANKATGGGYEGEDAY 301

  Fly   411 -----------------QKLRRLCTPETPEKFMLQDDKYLGLLEKTNWLFYVSLCLRYASEASAT 458
                             :.|||:.....|.   :::..:|..||.|:||.::.|.|..|...:..
  Rat   302 PHAELSFLDIHNIHVMRESLRRVRDIVYPH---VEEAHWLSSLESTHWLEHIKLLLTGAIRVADK 363

  Fly   459 LRSGVTCVLQE-SNGRDLCCVISSLAQLLLDPHFRTIDGFQSLVQKEWVALEHPFQRRLGHVYPA 522
            :.||::.||.. |:|.|....:::||.|:||..:|:|:||:.||||||::..|.|..|:||
  Rat   364 VASGLSSVLVHCSDGWDRTAQLTTLAMLMLDGFYRSIEGFEILVQKEWISFGHKFSSRIGH---- 424

  Fly   523 QPAGGNAELFDSEQSPVFLLFLDCVWQLLQQFPDEFEFTQTYLTTLWDSCFMPIFDTFQFDTQAQ 587
                |:....|:::||:||.|:|||||:.:|||..|||.:.:|..:.|..:...|.||..:.:|.
  Rat   425 ----GDKNHADADRSPIFLQFIDCVWQMTKQFPTAFEFNECFLVAILDHLYSCRFGTFLLNCEAA 485

  Fly   588 RLKAVTDSQLVLRPVWDWGEQFSDKDKMFFSNPLYQRQRGDLGAQAAAVAHRRSLAVGSKGAHGA 652
            |.:    .:|..|.|..|....|:||:  |:||.|.|:
  Rat   486 RER----QRLAERTVSVWSLINSNKDE--FTNPFYARE--------------------------- 517

  Fly   653 ASGVTPSRNTINPQLFATASSVPQDRYLQPAHRIFDLQVWDQCYYRWLPILDIRGGGQPQVDLYH 717
                                   .:|.:.|...:..|::|...|.||.|.:. :....|....|:
  Rat   518 -----------------------SNRVIYPVTSVRHLELWVNYYIRWNPRIR-QQQPHPMEQRYN 558

  Fly   718 RLLLSNIAKVQRCLDYQNFDDLPDAYYEFAGESRPNQHKDEKPDKEDEAEFVDGVERRRKPT--A 780
            .||.                 |.|.|.:                |.:|.:..       .||  .
  Rat   559 ELLA-----------------LRDDYIK----------------KLEELQLA-------TPTKLT 583

  Fly   781 KAATPTSGLTSVTGNLQ 797
            .::||.||...:...:|
  Rat   584 DSSTPPSGSAQIAPRMQ 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14411	NP_572972.1	PH-like	<114..225	CDD:473070	24/109 (22%)
		PTP-MTMR10-like	343..549	CDD:350385	66/245 (27%)
Mtm1	NP_001013065.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..40
		PH-like	44..143	CDD:473070	31/135 (23%)
		Myotub-related	162..489	CDD:461958	96/367 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	579..603		7/22 (32%)