DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14411 and Mtmr9

DIOPT Version :9

Sequence 1:	NP_001162756.1	Gene:	CG14411 / 32408	FlyBaseID:	FBgn0030582	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_001005761.1	Gene:	Mtmr9 / 282584	RGDID:	628840	Length:	549	Species:	Rattus norvegicus

Alignment Length:	531	Identity:	134/531 - (25%)
Similarity:	222/531 - (41%)	Gaps:	129/531 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 GRIAALHIVCKNFRLLKFAFQQQDSKMFGASDQGKLIASALVRFAYPMRHDLSFAYAHREPYYST 269
            |.:..:.|.||:||:::......:..:..||....|.....|...||      |.|   .|.:..
  Rat    64 GSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSVTLMYP------FFY---RPMFEV 119

  Fly   270 LGASGTSMYATKNDWARELIRCGATEWQVVSCASVQLLQNPLQAGKYTVPPHFVIPKSCSVDRFL 334
            : ..|...:..:.::  |......:||: :|..:.:....|      |.||..::|||.. |..|
  Rat   120 I-EDGWHSFLPEQEF--EFYSSATSEWR-LSYVNKEFSICP------TYPPTVIVPKSID-DEAL 173

  Fly   335 DLSRAFCDSRAAFWVYS-YGSSAALVRLAELQP-------AAQQDTKSENVMLELVRKCDAGRQL 391
            ....||... ..|.|.| |.....:|.:...||       ..::|.|..|..|.      ||::.
  Rat   174 RKVAAFRHG-GRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLR------AGKRG 231

  Fly   392 KLLQLTDRLPSIQDVLRA----------YQKLRRLCTPETPEKF-MLQD---------------- 429
            .|:.  .|..::....||          |.:.||:  .::.|:: :||:
  Rat   232 YLID--TRSLNVAQQARAKGGGFEQEAHYPQWRRI--HKSIERYHVLQESLIKLVEACNEQTHSM 292

  Fly   430 DKYLGLLEKTNWLFYVSLCLRYASEASATL-RSGVTCVLQESNGRDLCCVISSLAQLLLDPHFRT 493
            |::||.||.:|||.::...|..|..|:..: |.|.:.::..:.|.|....::||||::|:|..||
  Rat   293 DRWLGKLEASNWLTHIKEILTTACLAAQCIDREGASVLIHGTEGTDSTLQVTSLAQIILEPRSRT 357

  Fly   494 IDGFQSLVQKEWVALEHPFQRRLGHVYPAQPAGGNAELFDSEQSPVFLLFLDCVWQLLQQFPDEF 558
            |.||::|:::||:...||||:|.     ||.|..:::  ...::||||||||||||:|:|||..|
  Rat   358 IRGFEALIEREWLQAGHPFQQRC-----AQSAYCSSK--QKWEAPVFLLFLDCVWQILRQFPCSF 415

  Fly   559 EFTQTYLTTLWDSCFMPIFDTFQFDTQAQRLKAVTDSQLVLRPVWDWGEQFSDKDKMFFSNPLYQ 623
            ||.:.:|..|::..:...|.||..:::.:|.|.....:.:  .:|.|..:.|:..|  |:|||::
  Rat   416 EFNEHFLIMLFEHAYASQFGTFLGNSENERCKLKLQQKTM--SLWSWVNRPSELSK--FTNPLFE 476

  Fly   624 RQRGDLGAQAAAVAHRRSLAVGSKGAHGAASGVTPSRNTINPQLFATASSVPQDRYLQPAHRIFD 688
            ..                                        .|....|..||           .
  Rat   477 AN----------------------------------------NLVIWPSVAPQ-----------S 490

  Fly   689 LQVWDQCYYRW 699
            ||:|:..:.||
  Rat   491 LQLWEGIFLRW 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14411	NP_001162756.1	PH-like	<114..225	CDD:302622	6/19 (32%)
		PTPc	<400..587	CDD:304379	69/214 (32%)
		3-PAP	<666..732	CDD:289355	9/34 (26%)
Mtmr9	NP_001005761.1	PH-GRAM_MTMR9	1..97	CDD:275398	8/32 (25%)
Mtmr9	NP_001005761.1	Myotub-related	121..446	CDD:399535	100/352 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349526
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1089
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740