DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14411 and SPAC19A8.03

DIOPT Version :9

Sequence 1:	NP_001162756.1	Gene:	CG14411 / 32408	FlyBaseID:	FBgn0030582	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	NP_593789.1	Gene:	SPAC19A8.03 / 2542522	PomBaseID:	SPAC19A8.03	Length:	559	Species:	Schizosaccharomyces pombe

Alignment Length:	565	Identity:	124/565 - (21%)
Similarity:	214/565 - (37%)	Gaps:	159/565 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 NEITLNNIDH------IYTITELGRAASALQAARGMASHAGMSRRKKLEPFKQQNISGRIAALHI 212
            ||  ||...|      |::|:|.|:   .:..|..|.::..:...:|            ...:.|
pombe    19 NE--LNGTLHLTAYHSIFSISENGK---EIWTAYSMINNVKLCSNEK------------SFCIRI 66

  Fly   213 VCKNFRLLKFAFQQQDSKMFGASDQGKLIASALVRFAYPMRHDLSFAYAHREPYYSTLG-----A 272
            .|::|....:.||..:..|.......:|::...:...|..             ||...|     .
pombe    67 QCRDFMFFCWRFQSTEDAMDVYDTLQELMSINSINMLYAF-------------YYMPSGDEEKLP 118

  Fly   273 SGTSMYATKNDWARELI-----RCGA-TEWQVVSCASVQLLQNPLQAGKYTVPPHFVIPKS---- 327
            |....:..:|::.|..:     ..|| ..|::     .::.:|..:...|  |....:|.|
pombe   119 SSWKSFLLENEYRRMGVGDSTQADGAGGNWRI-----TKINENYSECHSY--PQALAVPASISDS 176

  Fly   328 -----C---SVDRFLDLSRAFCDSRAAFWVYSYGSSAALVRLAE-----LQPAAQQDTK------ 373
                 |   |.:||..|:            |.:.:|.::.|.::     .|..:.||.|
pombe   177 VIYYGCKYRSKNRFPTLT------------YLHKNSFSITRASQPLVGIRQNRSAQDEKLVEAIF 229

  Fly   374 -----------------SENVMLELV-----RKCDAGRQLKLLQL-TDRLPSIQDVL-RAYQKLR 414
                             |.|.|..:.     ...|..|..|.:.| .|.:..::|.| :....|:
pombe   230 ATSIIPGKENLIVDARPSTNAMANIAVGAGSENMDHYRFAKKIYLGIDNIHVMRDSLNKIVNALK 294

  Fly   415 RLCTPETPEKFMLQDDKYLGLLEKTNWLFYVSLCLRYASEASATLRSGVTCVLQE-SNGRDLCCV 478
            .......|        ..:.||.:::||.:::..|:.|.....|:......||.. |:|.|....
pombe   295 NTDISAAP--------PLIELLNRSSWLKHLANILQGAVLIVKTVHFRHAHVLVHCSDGWDRTSQ 351

  Fly   479 ISSLAQLLLDPHFRTIDGFQSLVQKEWVALEHPFQRRLGHV-----------YPAQP-------- 524
            :.:|.||.|||::|||:||.:||:|:|::..|.|..|..|:           |..:|
pombe   352 LCALPQLCLDPYYRTIEGFFALVEKDWLSFGHRFAERCCHLPGKRIFTIDSSYSEEPPQSSPSST 416

  Fly   525 ------------AGGNAELFDSEQSPVFLLFLDCVWQLLQQFPDEFEFTQTYLTTLWDSCFMPIF 577
                        :|.:.:..:...||||..|||||||::.|||:.|||.:.:|..|....:...:
pombe   417 LQYTFSTVRSALSGFSIDHSEKMMSPVFHQFLDCVWQIMDQFPNCFEFNERFLRRLLYHLYSCQY 481

  Fly   578 DTFQFDTQAQRLKAVTDSQLVLRPVWDWGEQFSDKDKMFFSNPLY 622
            .:|.::::.:|.:|...:.  .|.:||:  ..|.||:  |.||.|
pombe   482 GSFLYNSERERAQASVSTH--TRCIWDY--FLSRKDE--FKNPNY 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14411	NP_001162756.1	PH-like	<114..225	CDD:302622	15/76 (20%)
		PTPc	<400..587	CDD:304379	58/219 (26%)
		3-PAP	<666..732	CDD:289355
SPAC19A8.03	NP_593789.1	PH-like	4..94	CDD:302622	18/91 (20%)
SPAC19A8.03	NP_593789.1	Myotub-related	103..491	CDD:284109	93/427 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1089
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10807
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910