Protein Alignment CG14411 and mtmr3

DIOPT Version :10

• Sequence 1: NP_572972.1
• Gene: CG14411 / 32408
• FlyBaseID: FBgn0030582
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: XP_031747519.1
• Gene: mtmr3 / 100494490
• XenbaseID: XB-GENE-984945
• Length: 1224
• Species: Xenopus tropicalis
• Alignment Length: 788
• Identity: 171/788 - (21%)
• Similarity: 276/788 - (35%)
• Gaps: 263/788 - (33%)

  Fly   132 KRNQAITAPLIDLYQENT-YLGRNE---ITLNNIDHIYTITELGRAAS---ALQAARGMASHAGM 189
            :.::.:..|..:|:.|:| ::||.|   |:|:|    |.:....:.:|   .||....:...
 Frog    25 REDETLQVPFQELHGESTEFVGRAEDAVISLSN----YRLNIKYKESSINVPLQLIESVECR--- 82

  Fly   190 SRRKKLEPFKQQNISGRIAALHIVCKNFRLLKFAFQ-----QQDSKMFGASDQGKLIASALVRFA 249
                  :||:          ||:.||:.::::..|.     |:..|...|:.:.......|..||
 Frog    83 ------DPFQ----------LHLTCKDCKVIRSQFSSFEQVQEWQKRMNAALRPPSRIEDLFSFA 131

  Fly   250 YPMRHDLSF-AYAHREPYYSTLGASGTSMYAT-KNDWARELIRCG---ATEWQVVS-------CA 302
            |   |.... .||..:..:..|...|..:.:. ||    |:.|.|   ...|::.:       |.
 Frog   132 Y---HAWCMEVYASEKEQHGDLCRPGDHVISRFKN----EVERMGFDMDNAWRISNINEKFRLCP 189

  Fly   303 SVQLLQNPLQAGKYTVPPHFVIPKSCSVDRFLDLSRAFCD-SRAAFWVYSYGSSAALVRLAELQP 366
            |              .|...:|| :...|:.|:...:|.. .|....||.:.|:.|::.... ||
 Frog   190 S--------------YPQELIIP-AWITDKELESVASFRSWKRIPAVVYRHQSNGAVIARCG-QP 238

  Fly   367 AAQ----QDTKSENVMLELVRKC--DAGR--------------QL-------------------- 391
            ...    ::...|:::..:.:.|  |:.|              |:
 Frog   239 EVSWWGWRNADDEHLVQSVAKACATDSSRASPGKMTNGSCPRNQINGGVLTDVDFESSMSNIPPP 303

  Fly   392 --------KLLQLTDR------------------------------LPSIQDVLRAYQKLRRLCT 418
                    |||.|..|                              :.:|..:.:::|.||.|||
 Frog   304 ESPSVQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRKSFQSLRLLCT 368

  Fly   419 PETPEKFMLQDDKYLGLLEKTNWLFYVSLCLRYASEASATLRSGVTCVLQE-SNGRDLCCVISSL 482
            .      |.....:|..||.|.||.::|:.|:.:.....||......||.. |:|.|....|.:|
 Frog   369 Q------MPDPANWLSALEGTKWLQHLSMLLKSSLLVVHTLDKDQRPVLVHCSDGWDRTPQIVAL 427

  Fly   483 AQLLLDPHFRTIDGFQSLVQKEWVALEHPFQRRLGHVYPAQPAGGNAELFDSEQSPVFLLFLDCV 547
            ::|||||::|||:|||.||:.||:...|.|..|.||       |.|:|.. :|:.||||.:||||
 Frog   428 SKLLLDPYYRTIEGFQVLVETEWLDFGHKFADRCGH-------GENSEDL-NERCPVFLQWLDCV 484

  Fly   548 WQLLQQFPDEFEFTQTYLTTLWDSCFMPIFDTFQFDTQAQRLKAVTDSQLVLRPVWDWGEQFSDK 612
            .||.:|||..|||.:.:|..|....:..:|.||..:...:|    ::..:..|....|  .....
 Frog   485 HQLQRQFPCSFEFNEGFLVKLVQHTYSCLFGTFLCNNAKER----SEKHIQERTCSVW--SLLRA 543

  Fly   613 DKMFFSNPLYQRQRGDLGAQAAAVAHRRSLAVGSKGAHGAASGVTPSRNTINPQLFATASSVPQD 677
            ....|.|.||..|...:   ...|.|.|:|.:.|......:|..|||..:..|  :..:.|..:
 Frog   544 GNRAFKNLLYSSQSETV---LYPVCHVRNLMLWSAVYLPGSSPSTPSEESCTP--YPASGSATE- 602

  Fly   678 RYLQPAHRIFDLQVWDQCYYRWLPILDIRGGGQPQVDLYHRLLLSNIAKVQRCLDYQNFDDLPDA 742
               :||                                           |.|....:::||||.|
 Frog   603 ---EPA-------------------------------------------VCRLSKTRSYDDLPSA 621

  Fly   743 --------------------------YYEFAGESRPNQHKDEKPDKEDEAEFVDGVERRRKPTAK 781
                                      ..|.:|...|.:               ||.|..|:|...
 Frog   622 CDIMVPCMNRRSSDPSLNDKWQDHRRSLELSGLGNPGE---------------DGYEGDRQPLGA 671

  Fly   782 AATPTSGL 789
            ..:..:|:
 Frog   672 QLSMAAGV 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14411	NP_572972.1	PH-like	<114..225	CDD:473070	20/99 (20%)
		PTP-MTMR10-like	343..549	CDD:350385	74/284 (26%)
mtmr3	XP_031747519.1	PH-like	23..115	CDD:473070	23/112 (21%)
		PTP-MTMR3	169..486	CDD:350434	84/346 (24%)
		FYVE_MTMR3	1137..1206	CDD:277271