DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14411 and XB5960519

DIOPT Version :9

Sequence 1:	NP_001162756.1	Gene:	CG14411 / 32408	FlyBaseID:	FBgn0030582	Length:	843	Species:	Drosophila melanogaster
Sequence 2:	XP_031751608.1	Gene:	XB5960519 / 100216114	XenbaseID:	XB-GENE-5960520	Length:	563	Species:	Xenopus tropicalis

Alignment Length:	513	Identity:	126/513 - (24%)
Similarity:	201/513 - (39%)	Gaps:	120/513 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   167 ITELGRAASALQAARGMASHAGMSRRKKLEPFKQQNISGRIAALHIVCKNFRLLKFAFQQQDSKM 231
            |.||.....|:........:.|  |.:..|..::.::......:.:.||:.|::.......:..:
Frog    52 IAELWLLHCAVDKVEKSVQNIG--RLQNTENGQEMDVESGSGTVTLRCKDLRVIHMEIPGMEETL 114

  Fly   232 FGASDQGKLIASALVRFAYPMRHDLSFAYAHREPYYSTLGASGTSMYATKNDWAREL-------I 289
            ..|.....|.:..:|..:||        :..|.|.|| ||          :.|.|:.       :
Frog   115 NIARSVQALSSLDIVTLSYP--------FFFRPPGYS-LG----------HGWPRDTMENFYHKM 160

  Fly   290 RCGATEWQVVS-------CASVQLLQNPLQAGKYTVPPHFVIPKSCSVDRFLDLSRAFCDSRAAF 347
            |....:|::..       |.|              .|...::|:.|| |..|..:.||..: ..|
Frog   161 RAETDDWRLSEVNLDFKICPS--------------YPAKVIVPRICS-DETLQKAAAFRQA-GRF 209

  Fly   348 WVYSYGSSA---ALVRLAE-LQPAAQQDTKSENVMLEL------------VRKCDAGRQLK---- 392
            .|.||..||   ||:|.|: |...|....|.:..:|..            .|.....:|.:
Frog   210 PVLSYYHSANQTALLRSAQPLFGTAPHHCKHDEALLNAALMEQSSGFIIDTRSAQEAKQARNEGG 274

  Fly   393 -------------LLQLTDRLPSIQDVLRAYQKLRRLCTPETPEKFMLQDDKYLGLLEKTNWLFY 444
                         |.:..:|..::||.|     :|.:.|...|...|   .::|..|:...||.:
Frog   275 GTESKSRYRNWRVLHRPLERGHALQDSL-----VRLVVTCYDPSIGM---TRWLSKLQAARWLSH 331

  Fly   445 VSLCLRYASEASATLRSGVTCVLQE--------SNGRDLCCVISSLAQLLLDPHFRTIDGFQSLV 501
            |       .||.:|......|:.:|        .:|.|...:::|||||:|.|..||:||||.|:
Frog   332 V-------KEALSTAGLIAECIERECANVLVHGEDGTDNTLLLTSLAQLILCPESRTMDGFQDLI 389

  Fly   502 QKEWVALEHPFQRRLGHVYPAQPAGGNAELFDSEQSPVFLLFLDCVWQLLQQFPDEFEFTQTYLT 566
            ::||:...||||.|...       .|.::....::||.|||||||.|||.:|||...||.:.:|.
Frog   390 EREWLQAGHPFQLRCAQ-------SGWSQSRAQQESPHFLLFLDCCWQLGRQFPRALEFNERFLC 447

  Fly   567 TLWDSCFMPIFDTFQFDTQAQRLK-AVTDSQLVLRPVWDWGEQFSDKDKMFFSNPLYQ 623
            ||....:...:.:|..:.:.:|.: .|.|....|     ||.....|::....||:||
Frog   448 TLATHAYSSEYGSFLCNNEKERCQYEVQDRTHSL-----WGHLNQPKERQQLLNPIYQ 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14411	NP_001162756.1	PH-like	<114..225	CDD:302622	10/57 (18%)
		PTPc	<400..587	CDD:304379	62/194 (32%)
		3-PAP	<666..732	CDD:289355
XB5960519	XP_031751608.1	PH-GRAM_MTMR9	1..121	CDD:275398	11/70 (16%)
XB5960519	XP_031751608.1	Myotub-related	147..470	CDD:399535	94/360 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910