DRSC/TRiP Functional Genomics Resources

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Protein Alignment rut and Gucy2d

DIOPT Version :9

Sequence 1:NP_511156.2 Gene:rut / 32406 FlyBaseID:FBgn0003301 Length:2248 Species:Drosophila melanogaster
Sequence 2:NP_077356.1 Gene:Gucy2d / 79222 RGDID:620438 Length:1108 Species:Rattus norvegicus


Alignment Length:340 Identity:91/340 - (26%)
Similarity:155/340 - (45%) Gaps:84/340 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   162 PSVHISLTVYK---------IFTDALRYLEYNQLIANIVIFIGVNVAGLVVNIMMERAQRRTFLD 217
            ||:.::..::|         |....||.||  |..:|:            .:::.||.:      
  Rat   799 PSMDLTFDLFKGINKGRKTNIIDSMLRMLE--QYSSNL------------EDLIRERTE------ 843

  Fly   218 TRNCIASRLEIQDENEKLERLLLSVLPQHVAMQMK-NDILSPVAGQFHRIYIQKHENVSILFADI 281
                     |::.|.:|.:|||..:||..||..:| ...:.|          :..|.|::.|:||
  Rat   844 ---------ELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEP----------EYFEEVTLYFSDI 889

  Fly   282 VGFTVLSSQCSAQELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLPEPR-KDHAKCAVE 345
            ||||.:|:.....|:|.|||:|:..||.:...:...:::.:||.|...||||:.. :.||.....
  Rat   890 VGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPQRNGQRHAAEIAN 954

  Fly   346 MGLDMIDAIAT--VVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPG 408
            |.||::.|:.:  :....:|.:.:|:|:|:|..:.||:||...::.::.:.|..|:.|||.|.|.
  Rat   955 MSLDILSAVGSFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPY 1019

  Fly   409 RVHVTRAT---LDSLSGEYEVEA-------GHGDERSSYL--------------------RDHGV 443
            |:||..:|   |.:|...:::|.       |.|.|.:.:|                    .:||:
  Rat  1020 RIHVNMSTVRILRALDQGFQMECRGRTELKGKGVEDTYWLVGRVGFNKPIPKPPDLQPGASNHGI 1084

  Fly   444 DTFFIVPPPHRRKPL 458
            ....|  ||.|||.|
  Rat  1085 SLQEI--PPERRKKL 1097

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rutNP_511156.2 AC_N <17..255 CDD:292831 23/102 (23%)
CYCc 230..425 CDD:214485 64/201 (32%)
Guanylate_cyc 266..438 CDD:278633 57/184 (31%)
DUF1053 624..696 CDD:283888
SLC5-6-like_sbd <742..>893 CDD:294310
CYCc 924..1134 CDD:214485
Guanylate_cyc 954..1151 CDD:278633
Gucy2dNP_077356.1 PBP1_sensory_GC_DEF-like 58..434 CDD:380594
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 520..552
PK_GC-2D 540..814 CDD:270945 3/14 (21%)
HNOBA <823..868 CDD:400168 18/73 (25%)
CYCc 848..1039 CDD:214485 64/200 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1069..1108 9/31 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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