DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment rut and gucy2ca

DIOPT Version :9

Sequence 1:NP_511156.2 Gene:rut / 32406 FlyBaseID:FBgn0003301 Length:2248 Species:Drosophila melanogaster
Sequence 2:XP_009297342.1 Gene:gucy2ca / 572052 ZFINID:ZDB-GENE-091118-67 Length:1025 Species:Danio rerio


Alignment Length:479 Identity:126/479 - (26%)
Similarity:188/479 - (39%) Gaps:132/479 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   803 TSFQNDSHRKCSLPQYVSLSAAFAFLSVSVFLRLPIIFK-SLLVLGMG-TIYGLF---------- 855
            ||..:|...|..|.||.               |.|.:|: .|...|:| |...||          
Zfish   630 TSCCSDMAEKLYLVQYP---------------RGPNVFRPDLSFEGVGETEAELFVLIKSCWEED 679

  Fly   856 ---------IELSHQNIFECYDNRVNASIPLHLISLARIAIFMIAILVHGRLVEGTARLDFLWQL 911
                     ||.:...||....|:.|||...:||.               ||...:..|:.|.:.
Zfish   680 PEKRPDFKRIEGALGKIFSNLHNQANASYMDNLIR---------------RLQMYSRNLEHLVEE 729

  Fly   912 QASQEKKEMDVLQESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFY 976
            :.:..|.|.|...:.|    ..|||..| ...|....|...|||.:    |.:.|:.:..|    
Zfish   730 RTALYKAERDRADQLN----FMLLPGPV-VRSLKETGRVEPELYDE----VTIYFSDIVGF---- 781

  Fly   977 TEMDGSDQGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPN-S 1040
            |.:......:|.:.:||:|..:||.:|..   ..:.|::|:|..||...||          |. :
Zfish   782 TTICHHSTPMEVVDMLNDIYKNFDSILDH---HDVYKVETIGDAYMVASGL----------PRCN 833

  Fly  1041 VRRH-----MTAL--IEYVKA--MRHSLQEINSHSYNNFMLRVGINIGPVVAGVIGARKPQYDIW 1096
            ..||     :.||  :|::..  :|| |..|      ...:|:||:.||..|||:|.:.|:|.::
Zfish   834 GNRHAVDICLMALDILEFMGTFQLRH-LPGI------PLWIRIGIHSGPCAAGVVGNKMPRYCLF 891

  Fly  1097 GNTVNVASRMDSTGVPGYSQVTQEVVDSLVGSHFEFRC--RGTIKVKGKGDMVTYFLCDSGNKSL 1159
            |:|||.||||:|||:|....|::..:..|..:..||.|  ||...:||||..:||:        |
Zfish   892 GDTVNTASRMESTGLPLRIHVSESTIKILQRTDCEFECERRGETFLKGKGKEMTYW--------L 948

  Fly  1160 NGEVRNAMSLPQSLHAP---DYYMKVSQFPENRVNTDTYSKKENGHLYAGNGVEEQQLLLQHQHK 1221
            .|......|||    .|   :.:.::.|....|: ..|.:|:.|         |.::.|...|.:
Zfish   949 TGVTGQKYSLP----TPPTVENFQRLQQDLAERI-VSTLNKRGN---------ERRKTLSTRQRR 999

  Fly  1222 QHDPLPLPAPPPPVHHHLHQQQQQ 1245
            .|           .|.|.|....|
Zfish  1000 TH-----------THIHTHSGDGQ 1012

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rutNP_511156.2 AC_N <17..255 CDD:292831
CYCc 230..425 CDD:214485
Guanylate_cyc 266..438 CDD:278633
DUF1053 624..696 CDD:283888
SLC5-6-like_sbd <742..>893 CDD:294310 26/110 (24%)
CYCc 924..1134 CDD:214485 65/219 (30%)
Guanylate_cyc 954..1151 CDD:278633 66/208 (32%)
gucy2caXP_009297342.1 Periplasmic_Binding_Protein_Type_1 31..365 CDD:299141
PKc_like 428..698 CDD:304357 19/82 (23%)
Pkinase_Tyr 451..689 CDD:285015 16/73 (22%)
CYCc 736..929 CDD:214485 67/225 (30%)
Guanylate_cyc 763..950 CDD:278633 68/222 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

Return to query results.
Submit another query.