Protein Alignment rut and gucy1a1

DIOPT Version :10

• Sequence 1: NP_511156.2
• Gene: rut / 32406
• FlyBaseID: FBgn0003301
• Length: 2248
• Species: Drosophila melanogaster
• Sequence 2: NP_001296458.1
• Gene: gucy1a1 / 550420
• ZFINID: ZDB-GENE-050417-230
• Length: 679
• Species: Danio rerio
• Alignment Length: 494
• Identity: 112/494 - (22%)
• Similarity: 194/494 - (39%)
• Gaps: 154/494 - (31%)

  Fly    31 TLKLQRFSVLGVVALVFVLC-----GVMAALSLTFNNAATFHNIFNAIVCGLFAVVLVLLQCSVI 90
            |.::||:     :....:||     |:   |::.|.|......:|   ..|:......||.|:.:
Zfish   179 TPEIQRY-----IHQASILCLDKDPGL---LTVYFFNPLPSTELF---FSGIIQAAACLLYCTRV 232

  Fly    91 --------KD------HHLPTLCYGIL-----------LFTASICVVSMPTLGSVFPVDTKEVMA 130
                    ||      .|.|.|.|.::           :.|.:...:.:..|.|.||
Zfish   233 EVRMDVGGKDSGALQADHQPHLLYSVVVRDGRSLTPSPMRTHTSGDIPLSLLYSTFP-------- 289

  Fly   131 EGVWQIVFVVFLAYAMMPLQIWEAVA------------------FGIALPSVHISLTVYKIFTDA 177
                   |.:.|...|..|||.:.:.                  |.|..|.:..|      |.|.
Zfish   290 -------FHILLDQEMGLLQIGDGLRRRLGRCRDGQRRPAFNEHFAIVSPEIRAS------FQDI 341

  Fly   178 LRYLEYNQLI----------------------------ANIVIFIG---------VNVAGLVV-N 204
            |..|....|:                            .:.::|:|         :...||.: :
Zfish   342 LTMLNTQFLLRVKQHGASSADSPGKHMDLKGQMIFMSEMSALLFLGSPCVDKLEELTGRGLYLSD 406

  Fly   205 IMMERAQRRTFL-----DTRNCIASRL------------EIQDENEKLERLLLSVLPQHVAMQMK 252
            |.:..|.|...|     ..::.:..||            .:::|..:...||.::.|.:||.::.
Zfish   407 IPIHNALRDVVLVGEQTKAQDGLKKRLGKAKAALEQAHQALEEEKRRTVELLFTIFPGNVAQRLW 471

  Fly   253 NDILSPVAGQFHRIYIQKHENVSILFADIVGFTVLSSQCSAQELVRLLNELFGRFDQLAHDNHC- 316
            ..:  ||..       :|.::|::||:||||||.:.|:|:..::|.:|:||:.||     |:||
Zfish   472 QGL--PVQA-------KKFDHVTVLFSDIVGFTAICSRCTPMQVVNMLSELYTRF-----DHHCG 522

  Fly   317 ----LRIKILGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVL 377
                .:::.:||.|....||.:....||.....|.|.|::....|......::.||:|||:|.||
Zfish   523 ELDVYKVETIGDAYCVAGGLHKESPTHAVQIALMALKMMELSDEVTTPMGEVIRMRIGIHSGSVL 587

  Fly   378 CGVLGLRKWQFDVWSNDVTLANHMESGGEPGRVHVTRAT 416
            .||:|::..::.::.|:|||||..||...|.:::|:..|
Zfish   588 AGVVGVKMPRYCLFGNNVTLANKFESCSLPRKINVSPTT 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rut	NP_511156.2	AC_N	<17..255	CDD:318454	56/326 (17%)
		Guanylate_cyc	266..428	CDD:425528	54/156 (35%)
		Adcy_cons_dom	624..698	CDD:461877
		AcyC	742..1150	CDD:441717
		Guanylate_cyc	954..1151	CDD:425528
gucy1a1	NP_001296458.1	HNOBA	279..470	CDD:462234	35/211 (17%)
		Guanylate_cyc	476..647	CDD:425528	55/163 (34%)