DRSC/TRiP Functional Genomics Resources

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Protein Alignment rut and NPR2

DIOPT Version :9

Sequence 1:NP_511156.2 Gene:rut / 32406 FlyBaseID:FBgn0003301 Length:2248 Species:Drosophila melanogaster
Sequence 2:XP_024303324.1 Gene:NPR2 / 4882 HGNCID:7944 Length:1103 Species:Homo sapiens


Alignment Length:222 Identity:71/222 - (31%)
Similarity:121/222 - (54%) Gaps:23/222 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   230 DENEKLERLLLSVLPQHVAMQMKNDILSPVAGQFHRIYIQKHENVSILFADIVGFTVLSSQCSAQ 294
            :|..|.|.||..:||..||.|:|..         ..:..:..::|:|.|:||||||.||::.:..
Human   881 EEKRKAEALLYQILPHSVAEQLKRG---------ETVQAEAFDSVTIYFSDIVGFTALSAESTPM 936

  Fly   295 ELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLP-EPRKDHAKCAVEMGLDMIDAIAT-- 356
            ::|.|||:|:..||.:..:....:::.:||.|..||||| ...:.||.....|.|.::||:::  
Human   937 QVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFR 1001

  Fly   357 VVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLS 421
            :.......|.:|:|:|||.|..||:||:..::.::.:.|..|:.|||.|:..::||:..|.|:|.
Human  1002 IRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALD 1066

  Fly   422 ----------GEYEVEAGHGDERSSYL 438
                      |:.|:: |.|..|:.:|
Human  1067 ELGCFQLELRGDVEMK-GKGKMRTYWL 1092

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rutNP_511156.2 AC_N <17..255 CDD:292831 11/24 (46%)
CYCc 230..425 CDD:214485 66/207 (32%)
Guanylate_cyc 266..438 CDD:278633 59/184 (32%)
DUF1053 624..696 CDD:283888
SLC5-6-like_sbd <742..>893 CDD:294310
CYCc 924..1134 CDD:214485
Guanylate_cyc 954..1151 CDD:278633
NPR2XP_024303324.1 Periplasmic_Binding_Protein_Type_1 26..421 CDD:324556
PK_GC-A_B 521..848 CDD:270944
HNOBA <857..902 CDD:311573 9/20 (45%)
CYCc 881..1065 CDD:214485 64/192 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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