DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rut and Npr3

DIOPT Version :9

Sequence 1:	NP_511156.2	Gene:	rut / 32406	FlyBaseID:	FBgn0003301	Length:	2248	Species:	Drosophila melanogaster
Sequence 2:	XP_006232107.1	Gene:	Npr3 / 25339	RGDID:	3196	Length:	652	Species:	Rattus norvegicus

Alignment Length:	241	Identity:	42/241 - (17%)
Similarity:	73/241 - (30%)	Gaps:	87/241 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   510 AASALGGGVSVGGGGGGGGGGVARGSTCEANSGNVQVSEKGSRKVIRLQKI-------------- 560
            |.:.|.||.|.|||..|.|                  :.:..|:.:..|||
  Rat   132 ARALLAGGASSGGGDTGPG------------------NRRREREALAAQKIEVLVLLPRDDSYLF 178

  Fly   561 -LHATPPPHGMGYGSVVGSGGG-------------VDSGISGGGGCVS----GGIAGGGGVQVTV 607
             |....|.......||.|:|.|             .:....|.....|    ...|.|....:.:
  Rat   179 SLARVRPAIEYALRSVEGNGTGRKLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLIL 243

  Fly   608 GTNPNSTASTISRIHRH---------------NHKNNK---------SQSKVADKFKRPFRKRH- 647
            |......|:.::|:..|               .||:.:         :.:|:.:.....||..|
  Rat   244 GPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDTEYSHLTRVAPAYAKMGEMMLALFRHHHW 308

  Fly   648 SVAAHHQPTNRVNR------------FLSQAINARSVDCDKSEHVD 681
            |.||.....:::.|            |..:.::..:.:.|:::.:|
  Rat   309 SRAALLYSDDKLERNCYFTLEGVHEVFQEEGLHTSAYNFDETKDLD 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rut	NP_511156.2	AC_N	<17..255	CDD:292831
		CYCc	230..425	CDD:214485
		Guanylate_cyc	266..438	CDD:278633
		DUF1053	624..696	CDD:283888	14/95 (15%)
		SLC5-6-like_sbd	<742..>893	CDD:294310
		CYCc	924..1134	CDD:214485
		Guanylate_cyc	954..1151	CDD:278633
Npr3	XP_006232107.1	PBP1_NPR_C_like	165..556	CDD:107381	28/190 (15%)
		ANF_receptor	182..535	CDD:279440	27/173 (16%)
		TM_EphA1	587..618	CDD:214014
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900