Protein Alignment rut and Gucy1b2

DIOPT Version :10

• Sequence 1: NP_511156.2
• Gene: rut / 32406
• FlyBaseID: FBgn0003301
• Length: 2248
• Species: Drosophila melanogaster
• Sequence 2: XP_011243363.2
• Gene: Gucy1b2 / 239134
• MGIID: 2660873
• Length: 829
• Species: Mus musculus
• Alignment Length: 461
• Identity: 118/461 - (25%)
• Similarity: 208/461 - (45%)
• Gaps: 79/461 - (17%)

  Fly   802 TTSFQNDSHRKCSLPQYV-SLSAAFAFLSVSVFLR-----LPIIFKSLLVLGM-GTIYGLFIELS 859
            |..|..|.:.....||.. ::|:...|::....|:     :|..:||...|.: |.:  :::|..
Mouse   414 TQKFGLDEYFSIVHPQVTFNISSICKFINSQFILKTRREMMPEAWKSQPTLKLRGQM--IWMESL 476

  Fly   860 HQNIFECYD-----NRVNASIPLHLISLARIAIFMIAILVHGRLVEGTARLDFLWQLQASQEKKE 919
            ...:|.|..     ..:..| .:||..:|........||::.:.:   |.::...||:  ::|:|
Mouse   477 KCMVFMCSPKLRSLQELEES-KMHLSDIAPHDTTRDLILLNQQRL---AEMELSCQLE--KKKEE 535

  Fly   920 MDVL-------QESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYT 977
            :.||       ::..:.:|:.:||.|||     .|.:...::....:....::|:.|..|    |
Mouse   536 LRVLSNHLAIEKKKTETLLYAMLPEHVA-----NQLKEGKKVAAGEFETCTILFSDVVTF----T 591

  Fly   978 EMDGSDQGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVR 1042
            .:..:.:.::.:.:||.:.:.||.|   .....:.|::|:|..||.|.|:          |..|.
Mouse   592 NICAACEPIQIVNMLNSMYSKFDRL---TNIHDVYKVETIGDAYMVVGGV----------PVPVE 643

  Fly  1043 RHMTALIEYVKAMRHSLQEI-NSHSYNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRM 1106
            .|...:..:...||.|.:|: |..:.....:||||:.|||:|||:|.:.|:|.::|:|||.||||
Mouse   644 SHAQRVANFALGMRISAKEVMNPVTGEPIQIRVGIHTGPVLAGVVGDKMPRYCLFGDTVNTASRM 708

  Fly  1107 DSTGVPGYSQVTQEVVDSLVGSHFEFRCRGTIKVKGKGDMVTYFLCDSGNKSLNGEVRNAMSLPQ 1171
            :|.|:|....::.....:|....||...||.|:|||||.|.||||.    ::||......|..|.
Mouse   709 ESHGLPNKVHLSPTAHRALENKGFEIVTRGEIEVKGKGKMTTYFLI----RNLNATEVEIMGRPS 769

  Fly  1172 SLHAPDYYMKVSQFPENRV--------NTDTYSKKENGHLYAGN-----GVEEQQLLLQHQHKQH 1223
            :|...    |.:..|.|:|        |.|.:.::    :|..:     |...:...::.:|
Mouse   770 ALADG----KEASTPRNQVKKPRAVLSNMDHHQQQ----VYNSDPADVLGTASRTASVKGKH--- 823

  Fly  1224 DPLPLP 1229
             |.|||
Mouse   824 -PTPLP 828

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rut	NP_511156.2	AC_N	<17..255	CDD:318454
		Guanylate_cyc	266..428	CDD:425528
		Adcy_cons_dom	624..698	CDD:461877
		AcyC	742..1150	CDD:441717	97/367 (26%)
		Guanylate_cyc	954..1151	CDD:425528	62/197 (31%)
Gucy1b2	XP_011243363.2	HNOB	115..276	CDD:462233
		HNOBA	380..566	CDD:462234	35/164 (21%)
		Guanylate_cyc	572..754	CDD:425528	63/198 (32%)