DRSC/TRiP Functional Genomics Resources

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Protein Alignment rut and gcy-4

DIOPT Version :9

Sequence 1:NP_511156.2 Gene:rut / 32406 FlyBaseID:FBgn0003301 Length:2248 Species:Drosophila melanogaster
Sequence 2:NP_496218.2 Gene:gcy-4 / 191642 WormBaseID:WBGene00001531 Length:1136 Species:Caenorhabditis elegans


Alignment Length:344 Identity:90/344 - (26%)
Similarity:165/344 - (47%) Gaps:62/344 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   894 VHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQS 958
            |...|.|.|:.|    :::..:..||:.:.::.:..:|..:||..||     .:.:....:..:|
 Worm   831 VFSMLEEYTSSL----EVEVGERTKELTLEKKKSDILLGRMLPKQVA-----ERLKAGQAVEPES 886

  Fly   959 YAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMA 1023
            :..|.|.|:.:..|    |::.......:.:.|||::.::||.::::   ..:.|::::|..::.
 Worm   887 FDLVTVFFSDLVKF----TDLASKCSPFQVVNLLNDVFSNFDSIIEK---HDVYKVESIGDGFLC 944

  Fly  1024 VVGLIPEYKIQPNDPNSVRRHMTALI-------EYVKAMR--HSLQEINSHSYNNFMLRVGINIG 1079
            |.||       ||  .:...|:..::       |:.:..|  |..:|       ...||||||.|
 Worm   945 VSGL-------PN--RNGMEHIRQIVGMSLCFMEFCRNFRIPHLPRE-------RVELRVGINSG 993

  Fly  1080 PVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSLVGSH---FEFRCRGTIKVK 1141
            |.||||:|...|:|.::|:|||.||||:|.|.|....:::.....||.::   ||...||.:.:|
 Worm   994 PCVAGVVGLSMPRYCLFGDTVNTASRMESNGKPSMIHMSEAAHSLLVNNYPYQFETNSRGEVIIK 1058

  Fly  1142 GKGDMVTYFLCDSGNKSLNGEVRNAMSLPQSLHAPDYYMKVSQFPENRVNTDTYSKK------EN 1200
            |||.|.||:|.  |..||:.:  :...:.:..|.|   .|::.|.::.:.  .||.:      ||
 Worm  1059 GKGVMETYWLL--GKMSLSNQ--STPPITKVNHKP---RKIASFTDSELT--NYSFRSVSPYVEN 1114

  Fly  1201 GHLYAGNGVEEQQLLLQHQ 1219
               .:.|..||.:.:|:.:
 Worm  1115 ---LSDNDDEEIRRVLRRE 1130

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rutNP_511156.2 AC_N <17..255 CDD:292831
CYCc 230..425 CDD:214485
Guanylate_cyc 266..438 CDD:278633
DUF1053 624..696 CDD:283888
SLC5-6-like_sbd <742..>893 CDD:294310
CYCc 924..1134 CDD:214485 58/221 (26%)
Guanylate_cyc 954..1151 CDD:278633 62/208 (30%)
gcy-4NP_496218.2 PBP1_NPR_GC_like 29..457 CDD:107347
ANF_receptor 49..423 CDD:279440
PKc_like 558..819 CDD:304357
HNOBA <834..876 CDD:285003 11/50 (22%)
CYCc 855..1047 CDD:214485 56/219 (26%)
Guanylate_cyc 882..1070 CDD:278633 63/212 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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