DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rut and Npr3

DIOPT Version :9

Sequence 1:	NP_511156.2	Gene:	rut / 32406	FlyBaseID:	FBgn0003301	Length:	2248	Species:	Drosophila melanogaster
Sequence 2:	NP_032754.2	Gene:	Npr3 / 18162	MGIID:	97373	Length:	536	Species:	Mus musculus

Alignment Length:	273	Identity:	47/273 - (17%)
Similarity:	77/273 - (28%)	Gaps:	108/273 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   906 DFLWQLQASQEKKEMDVLQESNKRIL-----HNLLPAHVAAHFLDAQFRNNMELY---------- 955
            |.:..:|.|:....|....::.:||:     |.:.....|..        |:||:
Mouse   241 DIVRYIQGSERVVIMCASGDTIRRIMLAVHRHGMTSGDYAFF--------NIELFNSSSYGDGSW 297

  Fly   956 -----HQSYAK--------VGVIFASVPNFNEFYTEMDGS--DQGLECLRLLNEIIADFDELLKE 1005
                 |.|.||        |.::....|.|.:|..|:..|  .|||.....:|..:..|.:
Mouse   298 RRGDKHDSEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNEEDYVNMFVEGFHD---- 358

  Fly  1006 DRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVRRHMTALIEYVKAMRHSLQ---------E 1061
                                                     |::.||.|:...|:         :
Mouse   359 -----------------------------------------AILLYVLALHEVLRAGYSKKDGGK 382

  Fly  1062 INSHSYNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSLV 1126
            |...::|.....:.   |.|.....|.|...:.:...|...|.             ||||:....
Mouse   383 IIQQTWNRTFEGIA---GQVSIDANGDRYGDFSVVAMTDTEAG-------------TQEVIGDYF 431

  Fly  1127 GSHFEFRCRGTIK 1139
            |....|:.|..:|
Mouse   432 GKEGRFQMRSNVK 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rut	NP_511156.2	AC_N	<17..255	CDD:292831
		CYCc	230..425	CDD:214485
		Guanylate_cyc	266..438	CDD:278633
		DUF1053	624..696	CDD:283888
		SLC5-6-like_sbd	<742..>893	CDD:294310
		CYCc	924..1134	CDD:214485	41/248 (17%)
		Guanylate_cyc	954..1151	CDD:278633	37/220 (17%)
Npr3	NP_032754.2	PBP1_NPR_C_like	49..440	CDD:107381	45/267 (17%)
		ANF_receptor	66..419	CDD:279440	38/233 (16%)
		TM_EphA1	471..502	CDD:214014
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900