Protein Alignment rut and adcy4

DIOPT Version :9

• Sequence 1: NP_511156.2
• Gene: rut / 32406
• FlyBaseID: FBgn0003301
• Length: 2248
• Species: Drosophila melanogaster
• Sequence 2: XP_002934331.3
• Gene: adcy4 / 100497212
• XenbaseID: XB-GENE-984909
• Length: 1072
• Species: Xenopus tropicalis
• Alignment Length: 1210
• Identity: 423/1210 - (34%)
• Similarity: 615/1210 - (50%)
• Gaps: 229/1210 - (18%)

  Fly    26 LYQRYTLKLQRFSVLGVVALVFVLCGVMAALSLTFNNAATFHN-------IFNAIVCGLFAVVL- 82
            ||:.|....|::.|: ::.|:.||....|.:.:||....||.:       :|.|:  |:|:::.
 Frog    22 LYETYYRLTQQYPVI-LLLLLIVLAVCCALIIITFATGRTFSDNVGFLVTLFCAL--GVFSILFI 83

  Fly    83 ------VLLQCSVIKDHHLPTLCYGILLFTASICVVSMPTLGSVFPVDTKEVMA-EGVWQIVFVV 140
                  |:.:|..|         .|:::..   |:|   |||.||...:..|.| :.::..:||:
 Frog    84 PVCIKKVVQKCMQI---------IGVVILG---CLV---TLGYVFIFTSGLVSAWDQIYWTLFVI 133

  Fly   141 FLAYAMMPLQIWEAVAFGIALPSVHISLTVYKIFTDALRYLEYN----QLIANIVIFIGVNVAGL 201
            ...|.|:||.:..|:..|::....||  .|..::...:|.|..:    |:||:.||.:..||.|.
 Frog   134 ISLYTMLPLGMKWAIFAGLSCFVAHI--IVLSVYVSTVRLLPRDDVALQMIADAVILLCGNVIGG 196

  Fly   202 VVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQHVAMQMKNDILSPV------- 259
            ....:.|.|.:.|:.:..|.|.|||::..:..:.||||||:||.::|.:||.:|:..:
 Frog   197 YHKCVTESALKDTYHEAINFIHSRLKLVSQERQQERLLLSILPAYIATEMKAEIIERLKEKRPQP 261

  Fly   260 --AGQFHRIYIQKHENVSILFADIVGFTVLSSQCSAQELVRLLNELFGRFDQLAHDNHCLRIKIL 322
              ...||.:||::|::||||:|||||||:|||:||.:|||.:||||||:|||:|.||.|:|||||
 Frog   262 ENTNNFHNLYIKRHKDVSILYADIVGFTLLSSECSPKELVLMLNELFGKFDQIAKDNECMRIKIL 326

  Fly   323 GDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQ 387
            ||||||||||||...:|||..|.|||||..||..:.:||.|.:|||||:|:|.|||||:||:|||
 Frog   327 GDCYYCVSGLPEFLPNHAKNCVLMGLDMCQAIRKLRKATGVDINMRVGVHSGNVLCGVIGLQKWQ 391

  Fly   388 FDVWSNDVTLANHMESGGEPGRVHVTRATLDSLSGEYEVEAGHGDERSSYLRDHGVDTFFIVPPP 452
            :||||:|||||||||:||.|||||:|.|||..|..|||||.....:|..||:::.:.|:.:: .|
 Frog   392 YDVWSHDVTLANHMEAGGVPGRVHITEATLSHLENEYEVEDATLAQRDLYLKENNIKTYLVI-DP 455

  Fly   453 HRRKPLMLNTLGVRSAIGSRRKLSFRNVSNVVMQLLHTIKFSEPVPFSNIATGSFPSAASALGGG 517
            ........:.|..:||...:.:.|.|     :.:.|.:  :....||:::
 Frog   456 RANDGEAEDILPSKSAEVPKMRASVR-----MTRYLES--WGAEKPFAHL--------------- 498

  Fly   518 VSVGGGGGGGGGGVARGSTCEANSGNVQVSEKGSRKVIRLQKILHATPPPHGMGYGSVVGSGGGV 582
                                         |.:.|           ..|.||.:
 Frog   499 -----------------------------SHRDS-----------LVPEPHSI------------ 511

  Fly   583 DSGISGGGGCVSGGIAGGGGVQVTVGTNPNSTASTISRIHRHNHKNNKSQSKVADKFKRPFRKRH 647
                                                      :|..:...|.::..:.:  .|..
 Frog   512 ------------------------------------------SHSMDLPMSPLSQTWSQ--EKSR 532

  Fly   648 SVAAHHQPTNRVNRFLSQAINARSVDCDKSEHVDRLTLRFRQSDMEREYHKDFDL---GFTTA-- 707
            |....::..|. |.|....:.|......:|:..:|:||.|.....|:||... ||   .:.||
 Frog   533 STRETNESLND-NNFHIMEVLASQRQWKRSKDFNRITLYFNDKAAEKEYRLS-DLPSFKYYTACC 595

  Fly   708 ---MGCSLLLLIL----GAALQVT-ALPRTLILLLLF-LFAFIWVSAIL---MLL-----LAVRL 755
               ..|:.::.||    .||..:: .:.....||||| .||......||   .||     |::.|
 Frog   596 FFIFACNFIVQILVSHKNAAFGISYGISFFFFLLLLFTCFAGHLARCILKGPQLLHWLPSLSIAL 660

  Fly   756 KWIIWDISESFSLRMAITIFTVILIYSVGQVNVFTCVSDHPC---SGNGTTSFQNDSHRKCSLPQ 817
            ....|       ||:.:.:||::.:..:...|:| .:.|:.|   |.|.:.|...:.....|||.
 Frog   661 SSRPW-------LRVPLGVFTILTVLVMAVFNLF-FLPDNNCPQQSWNSSLSPDPEPQMLYSLPY 717

  Fly   818 Y-----VSLSAAFAFLSVSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFECYDN--RVNASI 875
            |     :.|.|..|||.::...:|.::..:|::..:     :|:| :|..:.:||.|  .:|.|.
 Frog   718 YMYCCILGLLACSAFLLMNFEAKLILLSIALVIYNV-----IFLE-THSWLSDCYVNWLYMNHSR 776

  Fly   876 P--------LHLISLARIAIFMIAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILH 932
            |        :..|||   .||...:|...|..|...||||||:.:...|::.::.::..|:.:|.
 Frog   777 PGILKEPKVMGSISL---FIFFFTLLALSRQNEYYCRLDFLWKRKFKMERERIETMENLNRVLLE 838

  Fly   933 NLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIA 997
            |:|||.||..|: .|.|.|.:||:|||..|.|:|||:|:|.|||||.|.:.:|||||||||||||
 Frog   839 NVLPADVAQQFI-GQNRRNEDLYYQSYDCVCVLFASIPDFKEFYTECDENHEGLECLRLLNEIIA 902

  Fly   998 DFDELLKEDRFRGIDKIKTVGSTYMAVVGL-IPEYKIQPNDPNSVRRHMTALIEYVKAMRHSLQE 1061
            ||||||.:.:|..::||||:||.|||..|| ....:..|.|.:....|:..::|:..|:...|..
 Frog   903 DFDELLSKPKFSSVEKIKTIGSAYMAATGLNATSGQENPQDGDRNYNHIGIMVEFAIALIGKLDL 967

  Fly  1062 INSHSYNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSLV 1126
            ||.||:|||.||||||.||||||||||:||||||||||||||||||||||.|..|||:|....|.
 Frog   968 INKHSFNNFKLRVGINHGPVVAGVIGAQKPQYDIWGNTVNVASRMDSTGVLGKIQVTEETTKVLE 1032

  Fly  1127 GSHFEFRCRGTIKVKGKGDMVTYFL-CDSGNKSLNGEVRN 1165
            ...::...||.|||||||.:.|||: .|.......|.|.|
 Frog  1033 KLGYKCERRGVIKVKGKGQLCTYFVSTDMARSGSQGNVLN 1072

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rut	NP_511156.2	AC_N	<17..255	CDD:292831	70/247 (28%)
		CYCc	230..425	CDD:214485	123/203 (61%)
		Guanylate_cyc	266..438	CDD:278633	114/171 (67%)
		DUF1053	624..696	CDD:283888	14/71 (20%)
		SLC5-6-like_sbd	<742..>893	CDD:294310	43/176 (24%)
		CYCc	924..1134	CDD:214485	118/210 (56%)
		Guanylate_cyc	954..1151	CDD:278633	117/197 (59%)
adcy4	XP_002934331.3	AC_N	<17..250	CDD:318454	70/247 (28%)
		Guanylate_cyc	270..427	CDD:306677	108/156 (69%)
		DUF1053	483..586	CDD:399378	25/217 (12%)
		Guanylate_cyc	859..1057	CDD:306677	117/197 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910