Protein Alignment rut and adcy6

DIOPT Version :9

• Sequence 1: NP_511156.2
• Gene: rut / 32406
• FlyBaseID: FBgn0003301
• Length: 2248
• Species: Drosophila melanogaster
• Sequence 2: XP_002935166.2
• Gene: adcy6 / 100493933
• XenbaseID: XB-GENE-1011902
• Length: 1239
• Species: Xenopus tropicalis
• Alignment Length: 1195
• Identity: 452/1195 - (37%)
• Similarity: 663/1195 - (55%)
• Gaps: 220/1195 - (18%)

  Fly    17 RFENDELECLYQRYTLKLQRFSVLGVVALVFVLCGVMAALSLTFNNAATFHNIFNAIVCGLFAVV 81
            :|::.:||.|||||..::.:.|:..::..:.::|.||.....|.......:....|:...||..:
 Frog   202 KFQSAKLERLYQRYFFQMNQSSLTMLMGALVLVCLVMLIFHCTHGEPQVVYVSVLAVAMALFLSL 266

  Fly    82 LVLLQCSVIKDHHLPTLCYGIL--LFTASICVVSMPTLGSVFPVDTKEVMAEGVWQIVFVVFLAY 144
            :|:...:.....::..:.|.::  ||...:..|.|.|..|.         :||:|..||.:::.|
 Frog   267 MVVCNRNGFHQDYMWIVSYLVIAVLFAVQVLGVLMVTPRSA---------SEGIWWSVFFIYIIY 322

  Fly   145 AMMPLQIWEAVAFGIALPSVHISLTVYKIFTDALRYLEYNQLIANIVIFIGVNVAGLVVNIMMER 209
            .::|:::..||..|:.|.|:|:.::.....||...   :.||.||::||:..|:.|:..:...|.
 Frog   323 TLLPVRMRAAVLSGLILSSLHLIISWRLNLTDIFL---WKQLSANVLIFLCTNIIGICTHYPAEV 384

  Fly   210 AQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQHVAMQMKNDILSPVAG-QFHRIYIQKHEN 273
            :||:.|.:||..|.:||.:|.||::.|||||||||:||||:||.||.:.... .||:||||||:|
 Frog   385 SQRQAFQETRGYIQARLHLQRENQQQERLLLSVLPRHVAMEMKEDINTKKEDMMFHKIYIQKHDN 449

  Fly   274 VSILFADIVGFTVLSSQCSAQELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLPEPRKD 338
            ||||||||.|||.|:|||:|||||..|||||.|||:||.:|||||||||||||||||||||.|.|
 Frog   450 VSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARAD 514

  Fly   339 HAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMES 403
            ||.|.||||:|||:||:.|.|.|.|.:|||||||:|||.|||||||||||||||||||||||||:
 Frog   515 HAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEA 579

  Fly   404 GGEPGRVHVTRATLDSLSGEYEVEAGHGDERSSYLRDHGVDTFFIVPPPHRRKPLMLNTLGVRSA 468
            ||:.||:|:|.|||..|:|:||||.|:|.||::||::|.:.||.:.....:||.        ..|
 Frog   580 GGKAGRIHITSATLKYLNGDYEVEPGNGGERNAYLKEHDIKTFLVTGCSQKRKE--------EKA 636

  Fly   469 IGSRRKLSFRNVSNVVMQLLHTIKFSEPVPFSNIATGSFPSAASALGGGVSVGGGGGGGGGGVAR 533
            :.:|.:.:..|.:..:.::.             :...|||
 Frog   637 MMARLQRARANSNEGLTRVW-------------VPERSFP------------------------- 663

  Fly   534 GSTCEANSGNVQVSEKGSRKVIRLQKILHATPPPHGMGYGSVVGSGGGVDSGISGGGGCVSGGIA 598
                         ..|||:...::                       |:|
 Frog   664 -------------RNKGSKAFRQM-----------------------GID--------------- 677

  Fly   599 GGGGVQVTVGTNPNSTASTISRIHRHNHKNNKSQSKVADKFKRPFRKRHSVAAHHQPTNRVNRFL 663
                                     .:.|:|::..:..:                 |.:.|:.||
 Frog   678 -------------------------ESSKDNRNTQEALN-----------------PEDEVDEFL 700

  Fly   664 SQAINARSVDCDKSEHVDRLTLRFRQSDMEREYHKDFDLGFTTAMGCSLLLLILGAALQVTALPR 728
            ::||:|||:|..:.:||.:..|.|:..|:|::|.|..|..|...:.|:||:......:|:...|.
 Frog   701 ARAIDARSIDQLRKDHVKKFLLTFQTPDLEKKYSKKVDDRFGGYVTCTLLVFCFICFIQIVIFPH 765

  Fly   729 TLILLLLFLFAFIWVSAILML--------LLAVRLKWIIWDISESFSLRMAITIFTVILIYSVGQ 785
            :.::|.::...||.:::||.:        |....|:.:...|.:|.:....|.|.|::|:::...
 Frog   766 SFLMLGVYTSVFIILASILFVCAIYSCIKLFPAALQGVSRKIVQSRTNSTLIGILTILLVFTSAF 830

  Fly   786 VNVFTCVSDH----PCSG---NGTTSFQNDSHRK-------------------CSLPQYVSLSAA 824
            ||:|.|  :|    .|:|   |.:..|.|..|.:                   |:.|:|.:.|..
 Frog   831 VNMFAC--NHRSLTDCAGQELNISYKFVNVCHLRMLNYSLSMDSPPCDSDKPLCNFPEYFNYSIL 893

  Fly   825 FAFLSVSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFECYDNRV------------------ 871
            .:.|:.||||::..|.|..|:|.:..:|.:.:|.....:|:.||..|
 Frog   894 LSLLACSVFLQISSIGKLALMLFIQILYIVIVEGPEVVLFDNYDLLVTVNALPINGTGDIEECLP 958

  Fly   872 NASIPLHLISLARIAIFMIAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILHNLLP 936
            ::.|.|..::...:.:|::|:.:|.:.||.||||||||:|||:.||:||:.||..|:|:|||:||
 Frog   959 SSKIALKFVTPVILTVFVLALYLHAQQVESTARLDFLWKLQATGEKEEMEQLQAYNRRLLHNILP 1023

  Fly   937 AHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIADFDE 1001
            ..||||||..:.||: |||:||...|.|:|||:.||:|||.|::.:::|:|||||||||||||||
 Frog  1024 KDVAAHFLAREHRND-ELYYQSCECVAVMFASICNFSEFYVELEANNEGVECLRLLNEIIADFDE 1087

  Fly  1002 LLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPND---PNSVRRHMTALIEYVKAMRHSLQEIN 1063
            ::.|::|:.::||||:||||||..||        ||   ....:.|:|||.:|...:|..::.||
 Frog  1088 IISEEKFKQLEKIKTIGSTYMAASGL--------NDTTYDKEGKTHITALADYAMKLREQMKYIN 1144

  Fly  1064 SHSYNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSLVGS 1128
            .||:|||.:::|:||||||||||||||||||||||||||||||||||:|...|||.::...|...
 Frog  1145 EHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGLPDCIQVTTDLYQVLAAK 1209

  Fly  1129 HFEFRCRGTIKVKGKGDMVTYFLCD 1153
            .::..|||.|||||||:|.||||.|
 Frog  1210 GYQMECRGVIKVKGKGEMTTYFLND 1234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rut	NP_511156.2	AC_N	<17..255	CDD:292831	74/239 (31%)
		CYCc	230..425	CDD:214485	143/195 (73%)
		Guanylate_cyc	266..438	CDD:278633	130/171 (76%)
		DUF1053	624..696	CDD:283888	18/71 (25%)
		SLC5-6-like_sbd	<742..>893	CDD:294310	44/202 (22%)
		CYCc	924..1134	CDD:214485	117/212 (55%)
		Guanylate_cyc	954..1151	CDD:278633	113/199 (57%)
adcy6	XP_002935166.2	AC_N	89..440	CDD:292831	76/249 (31%)
		CYCc	406..601	CDD:214485	143/194 (74%)
		Guanylate_cyc	442..615	CDD:278633	131/172 (76%)
		DUF1053	656..740	CDD:283888	29/214 (14%)
		PotE	<741..925	CDD:223605	44/185 (24%)
		CYCc	1007..1215	CDD:214485	119/216 (55%)
		Guanylate_cyc	1040..1233	CDD:278633	114/200 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	132	1.000	Domainoid score	I5058
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000