DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rut and gucy1b1

DIOPT Version :9

Sequence 1:	NP_511156.2	Gene:	rut / 32406	FlyBaseID:	FBgn0003301	Length:	2248	Species:	Drosophila melanogaster
Sequence 2:	XP_004911214.1	Gene:	gucy1b1 / 100379900	XenbaseID:	XB-GENE-950986	Length:	618	Species:	Xenopus tropicalis

Alignment Length:	207	Identity:	70/207 - (33%)
Similarity:	121/207 - (58%)	Gaps:	22/207 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 IASRLE-----IQDENEKLERLLLSVLPQHVAMQMKNDILSPVAGQFHRIYIQKHENVSILFADI 281
            :..||:     ::||.:|.:.||.||||..||.::::.  .||..       ::::||:|||:.|
Frog   372 LTDRLQHTLRALEDEKKKTDTLLYSVLPPSVANELRHK--RPVPA-------KRYDNVTILFSGI 427

  Fly   282 VGFTVLSSQCS----AQELVRLLNELFGRFDQLA---HDNHCLRIKILGDCYYCVSGLPEPRKDH 339
            |||....|:.:    |.::|.|||:::.|||.|.   ::.:..:::.:||.|..|||:|||...|
Frog   428 VGFNTFCSKHASGEGAMKIVNLLNDIYTRFDILTDSRNNPYVYKVETVGDKYMTVSGIPEPCVHH 492

  Fly   340 AKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESG 404
            |:....:.|||:: ||..|:.....:.:.:|||||.|:.||:|.|..::.::.|.|.|.:..|:.
Frog   493 ARSICHLALDMME-IAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETT 556

  Fly   405 GEPGRVHVTRAT 416
            ||.|:::|:..|
Frog   557 GEKGKINVSEYT 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rut	NP_511156.2	AC_N	<17..255	CDD:292831	13/37 (35%)
		CYCc	230..425	CDD:214485	68/194 (35%)
		Guanylate_cyc	266..438	CDD:278633	55/158 (35%)
		DUF1053	624..696	CDD:283888
		SLC5-6-like_sbd	<742..>893	CDD:294310
		CYCc	924..1134	CDD:214485
		Guanylate_cyc	954..1151	CDD:278633
gucy1b1	XP_004911214.1	HNOB	2..166	CDD:377902
		HNOBA	207..406	CDD:369471	13/33 (39%)
		Guanylate_cyc	412..605	CDD:306677	56/165 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910