Protein Alignment rut and dnajc27

DIOPT Version :10

• Sequence 1: NP_511156.2
• Gene: rut / 32406
• FlyBaseID: FBgn0003301
• Length: 2248
• Species: Drosophila melanogaster
• Sequence 2: NP_001096154.1
• Gene: dnajc27 / 100038110
• XenbaseID: XB-GENE-490420
• Length: 1116
• Species: Xenopus tropicalis
• Alignment Length: 1234
• Identity: 407/1234 - (32%)
• Similarity: 618/1234 - (50%)
• Gaps: 252/1234 - (20%)

  Fly    16 LRFENDELECLYQRYTLKLQRFSVLGVVALVFVL---CGVMAALSLTFNN---AATFHNIFNAIV 74
            |.|..:.||.|||.| .:.||...| :|.:||..   |.|:...::.::|   |:|.     ..|
 Frog    55 LTFAPESLENLYQTY-FRRQRHETL-LVLVVFAALFDCYVIVMCAVVYSNDKLASTL-----VAV 112

  Fly    75 CGLFAVVLVLLQCSV------IKDHHLPTLCYGILLFTASICVVSMPTLGSVFPVDTKEVMAEGV 133
            .||.|.:|:.:.|..      |....:|.:.:  :|..|.|    ...||..| ....|......
 Frog   113 VGLLAHLLLFVLCKFGLLPDRISRKFVPYILW--ILIAAQI----FSYLGLNF-AHFHEASDTVG 170

  Fly   134 WQIVFVVFLAYAMMPLQIWEAVAFGIALPSVH---ISLTVYKIFTDALR-YLEYNQLIANIVIFI 194
            || .|.||..:..:||::...|........:|   :.:|:.:...|::. .....|:::|:.|::
 Frog   171 WQ-AFFVFSFFITLPLRLTPIVLITAVSCGIHTLVLGVTIAQQQQDSINGNALLRQILSNVAIYL 234

  Fly   195 GVNVAGLVVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQHVA----MQMKNDI 255
            .....|::...|.:|..|:.||:.|..:..:|.:::::::.||||||:||:|:|    ..||.|.
 Frog   235 CTITVGIMSYYMADRKHRKAFLEARQSLEVKLNLEEQSQQQERLLLSILPKHIADEMLKDMKKDQ 299

  Fly   256 LSPVAGQFHRIYIQKHENVSILFADIVGFTVLSSQCSAQELVRLLNELFGRFDQLAHDNHCLRIK 320
            ......||:.:|:.:|||||||||||||||.|||.|||||||:||||||.|||:||..||.||||
 Frog   300 KQKELQQFNTMYMYRHENVSILFADIVGFTQLSSYCSAQELVKLLNELFARFDKLAAKNHQLRIK 364

  Fly   321 ILGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRK 385
            ||||||||:.|||:.|:|||.|::.|||.|:|||:.|.|.|...::||||:|:|.|:.||||.::
 Frog   365 ILGDCYYCICGLPDYREDHAACSIMMGLAMVDAISYVREKTKTDVDMRVGVHSGTVIGGVLGQKR 429

  Fly   386 WQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLSGEYEVEAGHGDERSSYLRDHGVDTFFIVP 450
            ||:||||.||||||.||:||.|||||::::|.|.|.||:|||.|.|..|..|||:.|:.|:.::.
 Frog   430 WQYDVWSTDVTLANKMEAGGIPGRVHISQSTYDCLKGEFEVEPGEGGTRCDYLREKGIVTYLVIV 494

  Fly   451 PPHRRKPLMLNTLGVRSAIGSRRKLSFRNVSNVVMQLLHTIKFSEPVPFSNIATGSFPSAASALG 515
            |   ::|  :|..|:...     |||..:......||::|
 Frog   495 P---KQP--INKNGINGV-----KLSLTSSHGNSPQLINT------------------------- 524

  Fly   516 GGVSVGGGGGGGGGGVARGSTCEANSGNVQVSEKGSRKVIRLQKILHATPPPHGMGYGSVVGSGG 580
                               ..|..:                    :|.|
 Frog   525 -------------------KECNGS--------------------IHTT---------------- 534

  Fly   581 GVDSGISGGGGCVSGGIAGGGGVQVTVGTNPNSTASTISRIHRHNHKNNKSQSKVADKFKRPFRK 645
                       |                |.|:......:|:...:..|.:.:.::.|..:|
 Frog   535 -----------C----------------TTPDENEELDTRVVNPSFPNPRRRLRLRDLAER---- 568

  Fly   646 RHSVAAHHQPTNRVNRFLSQAINAR-SVDCDKSEHVDRLTLRFRQSDMEREYHKDFDLGFTTAMG 709
               |....|....:|:.|::|:..| :|...|.::..||::||...:||..:..:.:.....|..
 Frog   569 ---VIDAQQNEQELNKLLNEALLERETVQVLKGKYTYRLSMRFINPEMETRFSVEKEKQSGAAFS 630

  Fly   710 CSLLLLILGAALQVTALPRTLILLLLFLFAFIWVSAILMLLLAV--------------------- 753
            ||.::|:..|.:|:...|..:...:.|:     :..||:|:|.:
 Frog   631 CSCVVLLFTAIVQILIDPMLIANYVTFV-----IGEILLLVLTICSLAAIFPRVFPKKLVAFSTW 690

  Fly   754 --RLKWI--IWDISESFSLRMAITIFTVILIYSVGQVNV-------FTCVSDHPCSGNGTTSFQN 807
              |.:|.  .|.:|..|.|.||..:..:..:...|.:|:       :.||.:
 Frog   691 IDRTRWARNTWAMSAIFILTMADIVDMLSCLQYYGTLNITSPAQEAWGCVEN------------- 742

  Fly   808 DSHRKCSLPQYVSLSAAFAFLS------VSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFEC 866
                    |:|.|..|..|.::      ||..::|.::....:.:|:..||      :.:.||:.
 Frog   743 --------PKYYSYIAVLALIATIMLVQVSHMVKLTLMLMITIAVGVVNIY------AWRPIFDD 793

  Fly   867 YDN-RVNASIPLHLIS----LARIAIFMIAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQES 926
            ||: |.|..:.|.:.|    .|.|.:.|::.....|.||..||..|||::...::|:::..::..
 Frog   794 YDSKRFNGYLALLVPSKYSMTAMIFVMMLSFYYFARHVEKLARTLFLWKIDVHEQKEKVYDMRRW 858

  Fly   927 NKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRL 991
            |:.::.|:||.|||.|||.::.|:. |||.|||.::||:|||:|||::||||...::.|:||||.
 Frog   859 NEALVTNMLPEHVARHFLGSKKRDE-ELYSQSYDEIGVMFASIPNFSDFYTEESINNGGIECLRF 922

  Fly   992 LNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVRR----------HMT 1046
            |||||:|||.||.|.:||.|.||||:||||||..|:.|:......: |::::          |:.
 Frog   923 LNEIISDFDALLDEPQFRCITKIKTIGSTYMAASGVTPDSNANGYN-NTIKKEEISDKERWQHLA 986

  Fly  1047 ALIEYVKAMRHSLQEINSHSYNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGV 1111
            .|.::..||:.:|..||..|:||||||:|:|.|.|:|||||||||.||||||||||||||:||||
 Frog   987 DLADFALAMKVTLMNINYQSFNNFMLRIGLNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV 1051

  Fly  1112 PGYSQVTQEVVDSLVGSHFEFRCRGTIKVKGKGDMVTYFL--CDSGNKSLNGEVRNAMSLPQSL 1173
            .|..||.:|..|.|....|.|..||.|.|||||:::|:||  .|.....:||   ::::||..:
 Frog  1052 MGNIQVVEETHDVLKEYGFRFVRRGPIYVKGKGELLTFFLKGRDKQGSFING---SSVTLPHQV 1112

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rut	NP_511156.2	AC_N	<17..255	CDD:318454	67/257 (26%)
		Guanylate_cyc	266..428	CDD:425528	108/161 (67%)
		Adcy_cons_dom	624..698	CDD:461877	17/74 (23%)
		AcyC	742..1150	CDD:441717	170/460 (37%)
		Guanylate_cyc	954..1151	CDD:425528	111/206 (54%)
dnajc27	NP_001096154.1	AcyC	128..472	CDD:441717	154/351 (44%)
		Guanylate_cyc	310..493	CDD:425528	117/182 (64%)
		Guanylate_cyc	885..1093	CDD:425528	113/208 (54%)