DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5347 and Trim2

DIOPT Version :9

Sequence 1:	NP_572970.1	Gene:	CG5347 / 32403	FlyBaseID:	FBgn0030578	Length:	285	Species:	Drosophila melanogaster
Sequence 2:	XP_011238598.1	Gene:	Trim2 / 80890	MGIID:	1933163	Length:	774	Species:	Mus musculus

Alignment Length:	93	Identity:	23/93 - (24%)
Similarity:	37/93 - (39%)	Gaps:	21/93 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 QRRAHNR------ECLEQHEQAMELSFAIARSKDK---MCGICFDTVVEKKGRERRFGILSKCKH 185
            |:||.:|      :......:...:...:.|..||   :|.||.:.....|        :..|.|
Mouse    10 QQRAGSRTAGPPCQWSRMASEGASIPSPVVRQIDKQFLICSICLERYKNPK--------VLPCLH 66

  Fly   186 IFCLTCIRTWRQAHQFEATVTRGCPECR 213
            .||..|::.:..||    ::|..||.||
Mouse    67 TFCERCLQNYIPAH----SLTLSCPVCR 90

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5347	NP_572970.1	ZnF_C3H1	4..30	CDD:214632
		PHA03096	<80..239	CDD:222981	23/93 (25%)
		RING	159..213	CDD:238093	14/53 (26%)
Trim2	XP_011238598.1	RING-HC_TRIM2	46..91	CDD:319681	16/57 (28%)
		Bbox2_TRIM2_C-VII	141..182	CDD:380882
		BBC	187..313	CDD:128778
		IG_FLMN	351..447	CDD:214720
		NHL_TRIM2_like	497..774	CDD:271330
		NHL repeat	515..554	CDD:271330
		NHL repeat	562..601	CDD:271330
		NHL repeat	604..640	CDD:271330
		NHL repeat	648..692	CDD:271330
		NHL repeat	701..741	CDD:271330
		NHL repeat	744..770	CDD:271330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910