DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5347 and Mkrn2

DIOPT Version :9

Sequence 1:NP_572970.1 Gene:CG5347 / 32403 FlyBaseID:FBgn0030578 Length:285 Species:Drosophila melanogaster
Sequence 2:NP_075779.2 Gene:Mkrn2 / 67027 MGIID:1914277 Length:416 Species:Mus musculus


Alignment Length:321 Identity:117/321 - (36%)
Similarity:163/321 - (50%) Gaps:62/321 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 RSQTICRFHLLGICRFGDLCRFSHDE--------TTPNDNQSPQIS--------EIADEVV---- 49
            :..|||:::..|.|.:|..||:.|.:        ..|..|.||...        :||..|:    
Mouse    32 KPSTICKYYQKGYCAYGARCRYDHTKPPAAAGGAVGPAPNPSPSSGLHSPHPSPDIATSVMRTHS 96

  Fly    50 ------ENEQVVASTSSYSRQMT----------------WANAPEFVPRYKANS---------AD 83
                  |.:.:|..    .|.:|                ..:.|:..|..|.:|         .|
Mouse    97 NEPGKREKKTLVLR----DRNLTGLAEDKTPPSKVNNPGGCSDPQTSPEMKPHSYLDAIRTGLDD 157

  Fly    84 FQATEGVQD---ICPY--GGSCIWGSKCSYPLHMEICKMCDLYCLHPMDQNQRRAHNRECLEQHE 143
            .:|:....:   :|||  .|.|.:|..|.| ||.::|::|.|..|||.|..||:||.:.|:...|
Mouse   158 LEASSSYSNEPQLCPYAAAGECRFGDACVY-LHGDMCEICRLQVLHPFDPEQRKAHEKMCMSTFE 221

  Fly   144 QAMELSFAIARSKDKMCGICFDTVVEK-KGRERRFGILSKCKHIFCLTCIRTWRQAHQFEATVTR 207
            ..||.:||...|:||:|.||.:.::|| ...||||||||.|.|.:||:|||.||.|.|||..:.:
Mouse   222 HEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCSHTYCLSCIRQWRCAKQFENPIIK 286

  Fly   208 GCPECRVFSEFVCPSAYWVDTKEEKDKLLSEYRAAMGAKDCKYFNGGLGKCPFGNKCFYRH 268
            .||||||.||||.||.|||:.:.:|::|:..::..||.|.||||..|.|.||||:||.|||
Mouse   287 SCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRH 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5347NP_572970.1 ZnF_C3H1 4..30 CDD:214632 9/24 (38%)
PHA03096 <80..239 CDD:222981 76/173 (44%)
RING 159..213 CDD:238093 29/54 (54%)
Mkrn2NP_075779.2 ZnF_C3H1 2..28 CDD:214632
ZnF_C3H1 35..55 CDD:214632 8/19 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 61..144 13/86 (15%)
PHA03096 <178..327 CDD:222981 72/149 (48%)
Makorin-type Cys-His 193..222 12/28 (43%)
RING 238..292 CDD:238093 29/53 (55%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 85 1.000 Domainoid score I8159
eggNOG 1 0.900 - - E1_KOG1039
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 254 1.000 Inparanoid score I3177
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG58455
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000752
OrthoInspector 1 1.000 - - mtm8837
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11224
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2178
SonicParanoid 1 1.000 - - X837
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1211.960

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