DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5347 and Mkrn2

DIOPT Version :9

Sequence 1:	NP_572970.1	Gene:	CG5347 / 32403	FlyBaseID:	FBgn0030578	Length:	285	Species:	Drosophila melanogaster
Sequence 2:	NP_001008315.1	Gene:	Mkrn2 / 297525	RGDID:	1310618	Length:	417	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	119/322 - (36%)
Similarity:	164/322 - (50%)	Gaps:	63/322 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RSQTICRFHLLGICRFGDLCRFSHDE--------TTPNDNQSPQ--------ISEIADEVV---- 49
            :..|||:::..|.|.:|..||:.|.:        ..|..:.||.        .|:||..|:
  Rat    32 KPSTICKYYQKGYCAYGARCRYDHTKPPAAAGGAVGPAPHPSPSSGLHSPHPSSDIATSVMRTHS 96

  Fly    50 ------ENEQVVASTSSYSRQMT-----------------WANAPEFVPRYKANS---------A 82
                  |.:.:|..    .|.:|                 ..|.|:..|..|.:|         .
  Rat    97 NEPRKREKKTLVLR----DRNLTGLAEDKTPPPSTVNNPGGCNDPQTSPEMKPHSYLDAIRTGLD 157

  Fly    83 DFQATEGV---QDICPY--GGSCIWGSKCSYPLHMEICKMCDLYCLHPMDQNQRRAHNRECLEQH 142
            |.:|:...   |.:|||  .|.|.:|..|.| ||.::|::|.|..|||.|..||:||.:.|:...
  Rat   158 DLEASSSYSNEQQLCPYAAAGECRFGDACVY-LHGDMCEICRLQVLHPFDPEQRKAHEKMCMSTF 221

  Fly   143 EQAMELSFAIARSKDKMCGICFDTVVEK-KGRERRFGILSKCKHIFCLTCIRTWRQAHQFEATVT 206
            |..||.:||...|:||:|.||.:.::|| ...||||||||.|.|.:||:|||.||.|.|||..:.
  Rat   222 EHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCSHTYCLSCIRQWRCAKQFENPII 286

  Fly   207 RGCPECRVFSEFVCPSAYWVDTKEEKDKLLSEYRAAMGAKDCKYFNGGLGKCPFGNKCFYRH 268
            :.||||||.||||.||.|||:.:.:|::|:..::..||.|.||||..|.|.||||:||.|||
  Rat   287 KSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRH 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5347	NP_572970.1	ZnF_C3H1	4..30	CDD:214632	9/24 (38%)
		PHA03096	<80..239	CDD:222981	77/173 (45%)
		RING	159..213	CDD:238093	29/54 (54%)
Mkrn2	NP_001008315.1	zf-CCCH_4	6..27	CDD:407881
		zf_CCCH_4	37..55	CDD:408151	6/17 (35%)
		PHA03096	<179..328	CDD:222981	72/149 (48%)
		RING-HC_MKRN2	236..293	CDD:319645	31/56 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	85	1.000	Domainoid score	I7980
eggNOG	1	0.900	-	-		E1_KOG1039
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I3107
OMA	1	1.010	-	-		QHG58455
OrthoDB	1	1.010	-	-		D1388677at2759
OrthoFinder	1	1.000	-	-		FOG0000752
OrthoInspector	1	1.000	-	-		mtm9084
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11224
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X837
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.940