DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5347 and Mkrn1

DIOPT Version :9

Sequence 1:	NP_572970.1	Gene:	CG5347 / 32403	FlyBaseID:	FBgn0030578	Length:	285	Species:	Drosophila melanogaster
Sequence 2:	XP_006236363.1	Gene:	Mkrn1 / 296988	RGDID:	1303251	Length:	481	Species:	Rattus norvegicus

Alignment Length:	353	Identity:	135/353 - (38%)
Similarity:	170/353 - (48%)	Gaps:	76/353 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 QTICRFHLLGICRFGDLCRFSHD-----------------------------------ETTPND- 35
            |..||:.:.|:|:.||.||:|||                                   |.|..|
  Rat    58 QVTCRYFMHGVCKEGDNCRYSHDLSDSPYGVVCKYFQRGYCVYGDRCRYEHSKPLKQEEVTATDL 122

  Fly    36 --NQSPQISEIADEVVENEQVVASTSSYSRQMT----------WANAPEFVP--RYKANSA---- 82
              ..||..|......|.:...:....:.||...          |.||.||||  .|...:|
  Rat   123 SAKPSPAASSSLPSGVGSLAEMNPGEAESRNPNFPTVGAGSEDWVNAIEFVPGQPYCGRTAPSCT 187

  Fly    83 ---------------DFQATEGVQDICPYG--GSCIWGSKCSYPLHMEICKMCDLYCLHPMDQNQ 130
                           :....|..:.:|||.  |.|.:|..|.| ||.:.|.||.|..|||||..|
  Rat   188 EVPLQGSVTKEESEKEPTTVETEKQLCPYAAVGECRYGENCVY-LHGDSCDMCGLQVLHPMDAAQ 251

  Fly   131 RRAHNRECLEQHEQAMELSFAIARSKDKMCGICFDTVVEKKG-RERRFGILSKCKHIFCLTCIRT 194
            |..|.:.|:|.||:.||||||:.||||.:||||.:.|.||.. .||||||||.|.|.:||.|||.
  Rat   252 RSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRK 316

  Fly   195 WRQAHQFEATVTRGCPECRVFSEFVCPSAYWVDTKEEKDKLLSEYRAAMGAKDCKYFNGGLGKCP 259
            ||.|.|||:.:.:.|||||:.|.||.||.|||:.||||.||:.:|:.||..|.|:||:.|.|.||
  Rat   317 WRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKACRYFDEGRGSCP 381

  Fly   260 FGNKCFYRH---HRRCDDNQTQSNAVNS 284
            ||..|||:|   ..|.::.|.|....:|
  Rat   382 FGGNCFYKHAYPDGRREEPQRQKVGTSS 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5347	NP_572970.1	ZnF_C3H1	4..30	CDD:214632	12/57 (21%)
		PHA03096	<80..239	CDD:222981	85/180 (47%)
		RING	159..213	CDD:238093	31/54 (57%)
Mkrn1	XP_006236363.1	ZnF_C3H1	55..81	CDD:214632	11/22 (50%)
		ZnF_C3H1	88..110	CDD:214632	0/21 (0%)
		PHA03096	<221..370	CDD:222981	83/149 (56%)
		RING	281..335	CDD:238093	31/53 (58%)
		MKRN1_C	400..479	CDD:292443	3/10 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	85	1.000	Domainoid score	I7980
eggNOG	1	0.900	-	-		E1_KOG1039
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I3107
OMA	1	1.010	-	-		QHG58455
OrthoDB	1	1.010	-	-		D1388677at2759
OrthoFinder	1	1.000	-	-		FOG0000752
OrthoInspector	1	1.000	-	-		mtm9084
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11224
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X837
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.940