DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5347 and Mkrn3

DIOPT Version :9

Sequence 1:NP_572970.1 Gene:CG5347 / 32403 FlyBaseID:FBgn0030578 Length:285 Species:Drosophila melanogaster
Sequence 2:NP_035876.2 Gene:Mkrn3 / 22652 MGIID:2181178 Length:544 Species:Mus musculus


Alignment Length:363 Identity:128/363 - (35%)
Similarity:171/363 - (47%) Gaps:102/363 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 QTICRFHLLGICRFGDLCRFSHD-------------------------------------ETTPN 34
            |.:||::|.|.|:.||.||:|||                                     |..|.
Mouse    95 QILCRYYLHGQCKEGDNCRYSHDLSGRRRSRGGQDAQPRASADRGPKMATRWEPPTQEVAEAPPA 159

  Fly    35 DNQS--PQISEIAD------EV-----------------VENEQVVASTSSYSRQMTWANAPEFV 74
            .:.|  |.|...|:      |:                 ::|..:.|..::.:....|..|.|||
Mouse   160 ASSSSLPLIGSAAERGFTEAEIDNAGIRSAAERGFSEAEIDNASLAAGAAAGAGAEGWEGAIEFV 224

  Fly    75 P--RYKAN-------SADFQATEGVQD---------------------------ICPYG--GSCI 101
            |  .|:..       .|..|:....::                           :|.|.  |.|:
Mouse   225 PGQPYRGRMVPPHGPEAPLQSPAIEREHMAMGMGMPMPVPMPMPVPMPVPMPLPLCRYAARGQCL 289

  Fly   102 WGSKCSYPLHMEICKMCDLYCLHPMDQNQRRAHNRECLEQHEQAMELSFAIARSKDKMCGICFDT 166
            .|.:|:|| |.|||.||....|||.|..|:.||.|.|:|.||:.||||||:.||.||:||||.:.
Mouse   290 RGDRCAYP-HGEICDMCGQQALHPWDAAQQEAHRRACVEAHERDMELSFAVQRSMDKVCGICMEV 353

  Fly   167 VVEKKG-RERRFGILSKCKHIFCLTCIRTWRQAHQFEATVTRGCPECRVFSEFVCPSAYWVDTKE 230
            |.||.. .:||||||..|.|.:||.|||.||.|.|||..:::.||:|||.|.||.||.:||:.:|
Mouse   354 VYEKADPSDRRFGILFSCNHTYCLRCIRRWRSATQFENRISKSCPQCRVSSGFVIPSEFWVEEEE 418

  Fly   231 EKDKLLSEYRAAMGAKDCKYFNGGLGKCPFGNKCFYRH 268
            ||:||:.:|:..|..|.|:||.||||.||||..|||:|
Mouse   419 EKEKLVQQYKEGMSQKACRYFAGGLGHCPFGEFCFYKH 456

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5347NP_572970.1 ZnF_C3H1 4..30 CDD:214632 13/59 (22%)
PHA03096 <80..239 CDD:222981 81/195 (42%)
RING 159..213 CDD:238093 28/54 (52%)
Mkrn3NP_035876.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..46
ZnF_C3H1 92..118 CDD:214632 12/22 (55%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 117..144 1/26 (4%)
Makorin-type Cys-His 302..329 13/26 (50%)
RING 347..401 CDD:238093 28/53 (53%)
MKRN1_C 467..542 CDD:292443
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 85 1.000 Domainoid score I8159
eggNOG 1 0.900 - - E1_KOG1039
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 254 1.000 Inparanoid score I3177
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG58455
OrthoDB 1 1.010 - - D1388677at2759
OrthoFinder 1 1.000 - - FOG0000752
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11224
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X837
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1110.940

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