DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15890 and si:dkey-5g14.1

DIOPT Version :9

Sequence 1:	NP_001285245.1	Gene:	CG15890 / 32401	FlyBaseID:	FBgn0030576	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	XP_009303600.1	Gene:	si:dkey-5g14.1 / 556497	ZFINID:	ZDB-GENE-091204-361	Length:	463	Species:	Danio rerio

Alignment Length:	487	Identity:	130/487 - (26%)
Similarity:	222/487 - (45%)	Gaps:	61/487 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 VEPILAAYIMPS-----VLSNLATQNLNLEKACRVNMAYGDEVCDALTRRQTANYTLEEETVQQM 131
            :||::|.|...|     ::.....:.|.||   ..|..|......:.....::|:|..:|.||:
Zfish     7 IEPVVAIYAFASFMLYPLIQQYVYRRLWLE---ITNSTYPVSENTSQCAANSSNHTSRQEEVQK- 67

  Fly   132 VARMAAWKTVIQSLFPCLLI-LFWGSWSDRHRRRKPCILIPVVGEFLGVVGLMLCVYFEQAPMEA 195
            .|.:.:..|.:.|:.|.|:: |...|:||: |.||..|::|::|..:..:..:...:|:   :..
Zfish    68 AASLFSMYTDLSSMIPSLIVTLLLVSYSDQ-RGRKITIIMPLIGTLIYTLSFLTVSFFQ---LNL 128

  Fly   196 AALTEAIFPS-LSGGWFTMLMGVFSYIADITTE-EDRTLRIGILNVCFSVGVPIGMAFSGVLLKQ 258
            ..|..|.|.| |.||..|||.|.|||:||:..: :.:|||:.::::...:...:....:|..|..
Zfish   129 YLLIVASFVSALFGGIGTMLGGCFSYVADLCEDGKQKTLRMAVVDMMIGMLAGVASISTGYFLHA 193

  Fly   259 IGFYGVFSISAAFYVIAFVYGFFFLEEPQ--SRPEKSA---EQKSLLADFFDKEHVVQTFRVAFK 318
            .||...|..||.|.|:..:|..|.|||.:  .|.|..|   ..::|....:           :..
Zfish   194 AGFNWPFFTSAIFQVVNLLYAIFILEETRVIDRSETLACCQALRNLACSIY-----------SLF 247

  Fly   319 KGENQRRKRVILLMIVVMVIIGPLH-GEMAVTYLFTRFRFN----WSEVEFSF---FSTYAMFTG 375
            .|.::||..|::|:|:....:..:: |.:::   ||.:..|    |:|:...:   .||....|.
Zfish   248 AGGSRRRTWVLVLLIITFSSLSFVNTGGLSI---FTLYELNEPLCWTEILVGYGSAASTSIFITS 309

  Fly   376 LIGVI---FCVGILSHKLNIDDALVGVLS-STSKILSSFVYAFATLPWHMYLGGLVEIFNGTAFI 436
            .:||.   .|:.      ||..|.:|:|| :.|.:::.|.....|    |:|..:..:|....|.
Zfish   310 FVGVFLFSLCLP------NIAIAFIGMLSVAVSMLMTGFAKTTLT----MFLVRIPAMFAIMPFP 364

  Fly   437 AMRSIATKLVSKDELGKVNSLFGVAEALMPMVFAPMYTTLYAATLRVLPGAFFLLGGGLTLFSVF 501
            .:||:.:|:|||.|.|.:.:.....|.|.....|..::.:||||:...||..||||.||.|..:.
Zfish   365 VLRSMMSKVVSKSEQGALFACVAFTETLSTNGSAASFSRIYAATVAWCPGFVFLLGAGLCLIPMS 429

  Fly   502 ---IFLWMYRFQVRQRRNLASADAESAAVKDP 530
               |...::.......:.|.|.|...|: .||
Zfish   430 LLGILKCVHPLDPNDTQALLSEDGTEAS-DDP 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15890	NP_001285245.1	MFS	135..507	CDD:119392	108/394 (27%)
CG15890	NP_001285245.1	MFS_1	135..470	CDD:284993	93/354 (26%)
si:dkey-5g14.1	XP_009303600.1	MFS	79..435	CDD:119392	107/383 (28%)
si:dkey-5g14.1	XP_009303600.1	MFS_1	81..393	CDD:284993	90/339 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I7409
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41733
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6513
orthoMCL	1	0.900	-	-		OOG6_100739
Panther	1	1.100	-	-	LDO	PTHR23507
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.860