DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15890 and Slc46a2

DIOPT Version :9

Sequence 1:	NP_001285245.1	Gene:	CG15890 / 32401	FlyBaseID:	FBgn0030576	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_001100122.1	Gene:	Slc46a2 / 298034	RGDID:	1310485	Length:	480	Species:	Rattus norvegicus

Alignment Length:	500	Identity:	118/500 - (23%)
Similarity:	206/500 - (41%)	Gaps:	73/500 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 RSWREKIRLVANNVTVEPILAAYIMPSVLSNLATQNLNLEKACRVNMAYGDEVCDALTRRQTANY 121
            |:|            :||::|:   ..|..:|....|.|.    :..::..:..|  :...:||.
  Rat    19 RTW------------IEPVVAS---TQVAGSLYDTGLLLV----LKESFASDARD--SSNYSANQ 62

  Fly   122 TL---EEETVQQMVARMAAWKTVIQSLFPCLLILFWGSWSDRHRRRKPCILIPVVGEFLGVVGLM 183
            :|   :|:..|:.::.......::..|.|.|.....|..|||: .||..|...::|..|..:||:
  Rat    63 SLGERQEDQQQKAISNFYIIYNLVVGLTPLLSAYVLGWLSDRY-HRKISICTAMLGFLLSRIGLL 126

  Fly   184 LCVYFEQAPME----AAALTEAIFPSLSGGWFTMLMGVFSYIADITTEEDRTLRIGILNVCFSVG 244
            |.|..:. |:|    ||||.     .|.||:.....||.:..:...::..|::|:.::::...:.
  Rat   127 LKVMLDW-PLEVMYGAAALN-----GLCGGFSAYWSGVMALGSLSCSQSRRSVRLILIDLVLGLA 185

  Fly   245 VPIGMAFSGVLLKQIGFYGVFSI--------SAAFYVIAFVYGFFFLEEPQ--SRPEK------- 292
            ...|...||.|.|||..:....:        .|||   |..|..|.|:.|:  |:|.|
  Rat   186 GFCGSMASGHLFKQIVGHSAQGLLLTACSVGCAAF---ALFYSLFVLKVPEAVSKPNKVHPTVDT 247

  Fly   293 ----SAEQKSLLADFFDKEHVVQTFRVAFKKGENQRRKRVILLMIVVMVIIGPLH--GEMAVTYL 351
                ....::|..|..||.::........|:..:|    .|:.::.|..|:..|.  |.:.|..|
  Rat   248 VSGMMGTYRTLDPDQQDKPNIQANPPTPGKEKPSQ----AIIALLFVGAIVYDLAVVGTLDVMAL 308

  Fly   352 FT-RFRFNWSEVEFSFFSTYAMFTG-LIGVIFCVGILSHKLNIDDALVGVLSSTSKILSSFVYAF 414
            |. :...:|::|:..    |.|.:| :|.:...:|:|.......|..:.::...|....:.:.||
  Rat   309 FVLKDPLHWNQVQLG----YGMASGYIIFITSFLGVLVFSRYFRDTTMIIIGMVSFGSGALLLAF 369

  Fly   415 ATLPWHMYLGGLVEIFNGTAFIAMRSIATKLVSKDELGKVNSLFGVAEALMPMVFAPMYTTLYAA 479
            ....:..|:...|.:|.......:||..:|||.....||:..:..:..||..:|.:.||..:|..
  Rat   370 VKKTYMFYIARAVMLFALIPITTIRSAMSKLVKDSSYGKIFVILQLCLALTGVVTSTMYNKIYQL 434

  Fly   480 TLRVLPGAFFLLGGGLTLFSVF-IFLWMYRFQVRQRRNLASADAE 523
            ||....|..|||...|:..::. |.:..|: ||...|....||.:
  Rat   435 TLNKFAGTCFLLSSFLSFLAIVPIGVVAYK-QVPGSRQGECADTQ 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15890	NP_001285245.1	MFS	135..507	CDD:119392	97/401 (24%)
CG15890	NP_001285245.1	MFS_1	135..470	CDD:284993	86/363 (24%)
Slc46a2	NP_001100122.1	MFS	86..433	CDD:119392	88/364 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347640
Domainoid	1	1.000	71	1.000	Domainoid score	I9200
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44504
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.850