DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15890 and SPAC14C4.07

DIOPT Version :9

Sequence 1:	NP_001285245.1	Gene:	CG15890 / 32401	FlyBaseID:	FBgn0030576	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_594912.1	Gene:	SPAC14C4.07 / 2541546	PomBaseID:	SPAC14C4.07	Length:	644	Species:	Schizosaccharomyces pombe

Alignment Length:	630	Identity:	121/630 - (19%)
Similarity:	236/630 - (37%)	Gaps:	167/630 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 YTVNHEPPPPSAMTTTQSTNSGVDKPIAKEKDNGTT---NPPVKRSWREK--------------- 62
            :::.||....|:.....:.:|..|...||.|:..:|   |.|:  |:.|.
pombe    51 HSLKHETNGASSSNNNVAKSSSHDSFKAKPKNYDSTSNSNEPI--SFNEPDSSNSHHNNESICNN 113

  Fly    63 ---IRLVANNVTVEPILAAYIMPSVLSN-------------LATQNL-----NLEKACRVNMAYG 106
               .|.:|...::.|:|   |:|....|             |..|.|     ||:.   ..::..
pombe   114 DNCCREIARRRSLSPLL---ILPLNFINAFSWGMIEIPLLFLLRQELCAIHYNLDP---TQLSPD 172

  Fly   107 DEVCDALTRRQTANYTLEEETVQQMVARMAAWKTVIQSLFPCLLILFWGSWSDRHRRRKPCILIP 171
            |.:|      :.|..|.....|:.....:||:..:..:       .::|:..|.:.||   :::.
pombe   173 DPIC------RLAEITTGVSKVRAAFGSLAAFLGLFST-------AYYGTMGDIYGRR---LVLF 221

  Fly   172 VVGEFLGVVGLMLCVYFEQAP------MEAAALTEAIFPSLSGGWFTMLMGVFSYIADITTEEDR 230
            :...|| ::|.:..:|...||      :.||||     ..|.|...|::....|::||.:..|.|
pombe   222 ITVSFL-LLGDLWLLYQSYAPKHPYFVLFAAAL-----KGLGGYISTVVASQNSFVADCSKTEFR 280

  Fly   231 TLRIGILNVCFSVGVPIGMAFSGVLLKQI-GFYGVFSISAAFYVIAFVYGFFFLEEPQSRPEKSA 294
            ...:|:....:.:|..:|.:.||.:::.. ..|.||.|::.|::|..:|.:..|.|.....| |.
pombe   281 AWYLGLNFAAYHLGTALGPSLSGFIVQYTPHMYYVFYITSTFWIIYLLYVWLILPESLDVSE-SK 344

  Fly   295 EQKSLLADF--------------------FDKEHVVQTFRVAFKKGENQRRKRVILLMIVV-MVI 338
            ||::.::.|                    .::......:.:.......:|...|:|..|:: :.:
pombe   345 EQQNKISGFSSIWRSCLEPLIILWPRSLCTEESCEFHQYDINADTHAGRRHWDVLLAAILISLTL 409

  Fly   339 IGPLHGEMAVTYLFTRFRFNWSEVEFSFFSTYAMFTGLIGVIFCVGILSHKLNIDDALVGVLSST 403
            :|.  |.|.:..|:|.::|.|..::.|...:...|...|.::....:||   .:.:.::..|.|:
pombe   410 LGA--GSMGLLPLYTDYKFGWGPMKASLILSTDSFASSITLVALFPLLS---KVIEKIIEKLYSS 469

  Fly   404 SKIL---------SSF-----VYAFATLP------------------------WHMYLG------ 424
            ..:.         ||.     |:::...|                        |:..||
pombe   470 EGLFEDPSRADNTSSLQGIRNVFSYLVRPGYSRSSILRGRTADEKYTIVKRDVWNAQLGYAIALS 534

  Fly   425 -----------------GLVEIFNGTAFIAMRSIATKLVSKDELGKVNSLFGVAEALMPMVFAPM 472
                             .:::..:......::|||...|..:..|:|.:.|.|.||:..::..|:
pombe   535 AAVLLAVAKSDVALFTAVIIQAISNMVVPCVQSIALNGVQSEYNGRVLAAFAVFEAVALIIRGPI 599

  Fly   473 YTTLYAATLRV-LPGAFFLLGGGL--TLFSVFIFLWMYRFQVRQR 514
            |..:|..:::| .|...|.|...:  ..|.:..|:.:||...|:|
pombe   600 YAFVYTESMKVSYPNMIFFLSAVIYGCCFIIIFFMRLYRPLNRKR 644

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15890	NP_001285245.1	MFS	135..507	CDD:119392	87/463 (19%)
CG15890	NP_001285245.1	MFS_1	135..470	CDD:284993	78/423 (18%)
SPAC14C4.07	NP_594912.1	MFS	190..>335	CDD:119392	36/160 (23%)
SPAC14C4.07	NP_594912.1	MFS_1	194..459	CDD:284993	59/286 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23507
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.940