DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15890 and slcr-46.2

DIOPT Version :9

Sequence 1:	NP_001285245.1	Gene:	CG15890 / 32401	FlyBaseID:	FBgn0030576	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_507773.1	Gene:	slcr-46.2 / 180270	WormBaseID:	WBGene00012811	Length:	475	Species:	Caenorhabditis elegans

Alignment Length:	473	Identity:	107/473 - (22%)
Similarity:	196/473 - (41%)	Gaps:	61/473 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 QNLNLEKACRVNMAYGDEVCDALTRRQTANYTLEEETVQQM--VARMAAWKTVIQSLFPCLLILF 153
            |:|...||| :.::...|...|...::|  |. .:.:|..|  |..||:      |...|:...|
Worm    22 QSLIFYKAC-ITLSNSTEPEIACKSKET--YA-RDNSVHSMSSVILMAS------STGLCVSAFF 76

  Fly   154 WGSW----SDRHRRRKPCILIPVVGEFLGVVGLMLCVYFEQAPMEAAALTEAIFPSLSGGWFTML 214
            ...|    || .:.||...|||.:|.|:....:::.|.:.:.......::|.|: ...||:.::.
Worm    77 TSRWVGHLSD-VKSRKLAFLIPFIGLFISDFTILIQVLYPRLSPYYFIVSEVIY-GFFGGYMSIT 139

  Fly   215 MGVFSYIADITTEE-DRTLRIGILNVCFSVGVPIGMAFSGVLLKQIGFYGVFSISAAFYVIAFVY 278
            .|.||.::.:.::: :|...|..|....|:|..:|...|. .||..|:.|    :|:|:::|...
Worm   140 SGAFSIVSTMHSDQRERAKGIARLEGTISLGSTVGFLISS-QLKNFGYLG----AASFFLVAHFI 199

  Fly   279 GFF---FLEEPQSRP---EKSAEQK------SLLADFFDKEHVVQTFRVAFKKGENQRRKRVILL 331
            .|.   |:.:|: :|   ||..::|      .||.|               ||.......:::..
Worm   200 AFMSAVFMRDPE-KPDLQEKCVKRKPFCHGTDLLKD---------------KKPPTSTNLKILYF 248

  Fly   332 MIVVMVIIGPLHGEMAVTYLFTRFRFNWSEVEFSFFSTYAMFTGLIGVI-FCVGILSHKLNIDDA 395
            .......  ...|...:.:.:.:.||.|...||.:..  ||.||:..:: ..:......|.|.|.
Worm   249 SFACSYF--AFIGSTRILFFYLKHRFFWGAEEFGYLK--AMNTGMTTIMSLALYPFLKNLGITDI 309

  Fly   396 LVGVLSSTSKILSSFVYAFATLPWHMYLGGLVEIFNGTAFIAMRSIATKLVSKDELGKVNSLFGV 460
            .:.:....::.:....||.|...|.:::....|:|:.....||||.....|.:.|.|...||..|
Worm   310 RLAIFGLLTRSIGRAWYAVAWEGWTVFIVVFFEMFSKFPATAMRSSIATNVGEHERGLAFSLVAV 374

  Fly   461 AEALMPMVFAPMYTTLYAATLRVLPGAFFLLGGGLTLFSVFIFLWMYRFQVRQRRN---LASADA 522
            .|||..:..:.::...:..:|.|.|...|::...:.|.::.:.:...|:......|   |.::..
Worm   375 IEALCNLTSSWVFHLAWPLSLNVFPQLSFVIMPIIILPAITLMILNMRYLEAPELNPEDLTTSIK 439

  Fly   523 ESAAVKDPNGNINAIEAL 540
            :|..:.: |.|::..|||
Worm   440 KSDDISE-NVNVHDPEAL 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15890	NP_001285245.1	MFS	135..507	CDD:119392	86/389 (22%)
CG15890	NP_001285245.1	MFS_1	135..470	CDD:284993	81/352 (23%)
slcr-46.2	NP_507773.1	MFS	58..419	CDD:391944	88/393 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	91	1.000	Domainoid score	I4859
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I3339
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	1	1.000	-	-		otm14635
orthoMCL	1	0.900	-	-		OOG6_100739
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.830