Protein Alignment CG15890 and SLC46A1

DIOPT Version :10

• Sequence 1: NP_572968.1
• Gene: CG15890 / 32401
• FlyBaseID: FBgn0030576
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_542400.2
• Gene: SLC46A1 / 113235
• HGNCID: 30521
• Length: 459
• Species: Homo sapiens
• Alignment Length: 488
• Identity: 114/488 - (23%)
• Similarity: 192/488 - (39%)
• Gaps: 95/488 - (19%)

  Fly    49 GTTNPPVKRSWR-----------EKIRLVANNVTV--EPILAAYIMPSVLSNLATQNLNLEKACR 100
            |:.:||.|...|           |.:..:||...|  .|:...|:.....::|..........|
Human     3 GSASPPEKPRARPAAAVLCRGPVEPLVFLANFALVLQGPLTTQYLWHRFSADLGYNGTRQRGGC- 66

  Fly   101 VNMAYGDEVCDALTRRQTANYTLEEETVQQMVARMAAWKTV---IQSLFPCLLILFWGSWSDRHR 162
                          ..::|:.|::|  |:.:.:....:..|   :..||...|:   |:|||...
Human    67 --------------SNRSADPTMQE--VETLTSHWTLYMNVGGFLVGLFSSTLL---GAWSDSVG 112

  Fly   163 RRKPCILIPVVGEFLG------VVGLMLCV-YFEQAPMEAAALTEAIFPSLSGGWFTMLMGVFSY 220
            || |.:::..:|..|.      ||.|.|.| ||         :...|..:|.|.:..:|...|:.
Human   113 RR-PLLVLASLGLLLQALVSVFVVQLQLHVGYF---------VLGRILCALLGDFGGLLAASFAS 167

  Fly   221 IADITTEEDRTLRIGILNVCFSVGVPIGMAFSGVLLKQIGFYGVFSISAAFYVIAFVYGFFFLEE 285
            :||:::...||.|:.:|.....|...:.....|..|:..|:...|.::.|..:...:|..|...|
Human   168 VADVSSSRSRTFRMALLEASIGVAGMLASLLGGHWLRAQGYANPFWLALALLIAMTLYAAFCFGE 232

  Fly   286 PQSRPEKSAEQKSLLADFFDKEHVVQTFRVAFKKGENQRRKRVILLMIVVMVIIGPLHGEMAVTY 350
            ....|:.:.     |..|.....:||.: ||  ....:.||.:.|..:.:.|:|....|...:..
Human   233 TLKEPKSTR-----LFTFRHHRSIVQLY-VA--PAPEKSRKHLALYSLAIFVVITVHFGAQDILT 289

  Fly   351 LFTRFRFNWSEVEFSFFSTYAMFTGLIG-------VIFCVGILSHKL---NIDDALVGVLSSTSK 405
            |:          |.|  :.....:.|||       :.:...:|:.||   .:.||.|..:.....
Human   290 LY----------ELS--TPLCWDSKLIGYGSAAQHLPYLTSLLALKLLQYCLADAWVAEIGLAFN 342

  Fly   406 ILSSFVYAFATLPWHMYLGGLVEIFNGTAFIAM------RSIATKLVSKDELGKVNSLFGVAEAL 464
            ||...|:||||:...|:.|      .|..|:::      |:..:|||.:.|.|.:.|......:|
Human   343 ILGMVVFAFATITPLMFTG------YGLLFLSLVITPVIRAKLSKLVRETEQGALFSAVACVNSL 401

  Fly   465 MPMVFAPMYTTLYAATLRVLPGAFFLLGGGLTL 497
            ..:..:.::.:||.|||..:.|..||||.||.|
Human   402 AMLTASGIFNSLYPATLNFMKGFPFLLGAGLLL 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15890	NP_572968.1	MFS_SLC46	69..507	CDD:340944	106/457 (23%)
SLC46A1	NP_542400.2	MFS_SLC46A1_PCFT	22..444	CDD:341007	109/469 (23%)