DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15890 and LOC100487354

DIOPT Version :9

Sequence 1:	NP_001285245.1	Gene:	CG15890 / 32401	FlyBaseID:	FBgn0030576	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	XP_017953038.2	Gene:	LOC100487354 / 100487354	-ID:	-	Length:	462	Species:	Xenopus tropicalis

Alignment Length:	510	Identity:	113/510 - (22%)
Similarity:	201/510 - (39%)	Gaps:	91/510 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 RSWREKIRLVANNVTVEPILAAYIMPSVLSNLATQNLNLEKACRVNMAYGDEVCDALTRRQTANY 121
            |:|            :||::|.       :.:|:...:......|...|...:..:.:.|
Frog     3 RTW------------IEPVVAG-------AQIASSFYDTGLLMTVENYYNQTIISSNSSR----- 43

  Fly   122 TLEEETVQQMVARMAAWKTVIQSLFPCLLILFWGSWSDRHRRRKPCILIPVVGEFLGVVGLMLCV 186
               ::.:|:.::.......|:..:.|.|........||: ...|..|.:|:.|..:..:.|:..:
Frog    44 ---DDDLQKAISNFYIIYNVVMGMTPLLSAYILAKISDK-TSTKVTICVPLTGYLISRMFLLFVI 104

  Fly   187 YFEQAPMEAAALTEAIFPSLSGGWFTML-MGVFSYIADITTEEDRTLRIGILNVCFSVGVPIGMA 250
            .||. |:| .....|.|..|: ||||.. .||.::.:..:||..|:|::.|:.:.:.:....|..
Frog   105 LFEW-PIE-VIFGSAAFNGLT-GWFTTYWAGVMAWASLASTESKRSLKLIIIELVYGLAGFAGSL 166

  Fly   251 FSGVLLKQIGF---YGVF--SISAAFYVIAFVYGFFFLEEPQSR---PEKSAE--------QKSL 299
            .||.:...:..   .|..  |.|...|....:|..|.|:.|.:.   .|::.|        |:|:
Frog   167 VSGYIFVHLNINKHQGTILASCSTGCYAFCVLYSIFILKMPDAETCLEERNTEGSSINEASQESI 231

  Fly   300 LAD---FFDKEHVVQTFRVAFKKGENQRRKRVILLMIVVMVI--IGPLHGEMAVTYLFTRFRFNW 359
            .:|   ..||    .|...|....:....|.||:.|.|..::  |.....:..:.....:...||
Frog   232 NSDCALLNDK----PTNNTAINPSDVASSKCVIICMFVSAIVYNIAVTATDDVINVFVLKKPLNW 292

  Fly   360 SEVEFSF-----FSTYAMFTGLIGV-IF--CVGILSHKLNIDDALVGVLSSTSKILSSFVYAFAT 416
            ..||..:     :.||  .|..:|| ||  |.|      ::...:.|::|.:..||   :.||..
Frog   293 GPVEVGYGNAAAYMTY--ITSFLGVYIFSKCFG------DLGLIITGMISFSCGIL---IMAFVR 346

  Fly   417 LPWHMYLGGLVEIFNGTAFIAMRSIATKLVSKDELGKVNSLFGVAEALMPMVFAPMYTTLYAATL 481
            ..:..|:...|.:|:......:|||.:|.|.....|:|..:..:|..::.:..:..:..||.|||
Frog   347 WTYLYYIARAVMLFSLITTPTIRSIISKHVKGSSYGQVFVVLQMAIEVIAVSSSAGFNKLYQATL 411

  Fly   482 RVLPGAFFLLG---GGLTLFSVFIFLWMYRFQVRQRRNLASADAESAAVKDPNGN 533
            ....|..||:.   |.|::..|.|.:      .:|.:..|:.|.||      ||:
Frog   412 DWFSGFCFLVFSALGFLSIIPVIITV------CKQHQTCATRDNES------NGS 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15890	NP_001285245.1	MFS	135..507	CDD:119392	96/404 (24%)
CG15890	NP_001285245.1	MFS_1	135..470	CDD:284993	84/364 (23%)
LOC100487354	XP_017953038.2	MFS_SLC46A2_TSCOT	3..437	CDD:341008	106/479 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47543
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020