Protein Alignment NetB and Ntng1

DIOPT Version :9

• Sequence 1: NP_001162753.1
• Gene: NetB / 32400
• FlyBaseID: FBgn0015774
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: XP_006502418.1
• Gene: Ntng1 / 80883
• MGIID: 1934028
• Length: 581
• Species: Mus musculus
• Alignment Length: 623
• Identity: 143/623 - (22%)
• Similarity: 206/623 - (33%)
• Gaps: 282/623 - (45%)

  Fly    51 AYGNPVQASSVCGAQQPERYCELLRDGNAGECRSCEQQRYGPAALTDLNNPSNVTCWRSGAVNVP 115
            |.|||...::.|.|..||                   ..:.|..:.|.......|.|:|....
Mouse    81 AMGNPYMCNNECDASTPE-------------------LAHPPELMFDFEGRHPSTFWQSATWK-- 124

  Fly   116 HDPDSAPPDNVTLTLSLGKKYELT-YISLSFCPRSPRPDSLAIFKSSDFGQTWQPFQFYSSQC-Q 178
               :...|..|.:|||..|..||| .|.::|  .|.|||.:.:.||.|:|:||||:|:|::.| .
Mouse   125 ---EYPKPLQVNITLSWSKTIELTDNIVITF--ESGRPDQMILEKSLDYGRTWQPYQYYATDCLH 184

  Fly   179 KFYGRPDRAK-ISKFNEQEARCINSQHDTGGAA----------QRFAF---------NTLEGRPS 223
            .|:..|...| :|:....|..| ..::.||.:.          .||||         .:|.|:
Mouse   185 AFHMDPKSVKDLSQHTVLEIIC-TEEYSTGYSTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQ-- 246

  Fly   224 ANDLDSSLVLQDWVTATDIRVVFHRLELPPQLLKVKNANAFSDEMGGSREEDEDDDADLELDGEQ 288
               ||::..|:|:.|.||:|:         :||:......|.||
Mouse   247 ---LDTTKKLRDFFTVTDLRI---------RLLRPAVGEIFVDE--------------------- 278

  Fly   289 DEYDYNLQDNDSADAGYDEYEEPKKHLELDDDHLHLDYASDGESVVKRQGKHKGSAYEKHYQSKL 353
                                             |||                  :.|
Mouse   279 ---------------------------------LHL------------------ARY-------- 284

  Fly   354 AATTPPQQPPKVTPPGKVTPPSTAAPSAAASAVTLPISQHYAVSDFAVGGRCKCNGHASECVATV 418
                                                   .||:||..|.||||||.||:.|:...
Mouse   285 ---------------------------------------FYAISDIKVRGRCKCNLHATSCLYDN 310

  Fly   419 SSGSGTALSDQDDGQDEDTPSAPSLANHFGRSTQMSAKLTMTCACKHNTAGPECERCKPFYFDRP 483
            |.                                      :||.|:|||.||:|.:||..|..||
Mouse   311 SK--------------------------------------LTCECEHNTTGPDCGKCKKNYQGRP 337

  Fly   484 WG--------RATDND----------------------------------------------ANE 494
            |.        :.|.|.                                              ||.
Mouse   338 WSPGSYLPIPKGTANTCIPSISSIGTPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANH 402

  Fly   495 CKMCQCNGHARRCRFNLELYKLSGRVSGGVCYNCQHDTTGRYCHYCREGYYRDATKPPNHRKVCK 559
            .:.|:|.||:.||.: ::|      ::..:|.:|:|:|.|::|..||.||:|:|:...:...||.
Mouse   403 KRDCECFGHSNRCSY-IDL------LNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCI 460

  Fly   560 RCDCHPVGSTGKTCNHLSGQCPCKEGVTGLTCNRCARG 597
            .|.|:|:||....||. ||.|.||.|.||..|:.|..|
Mouse   461 ECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPG 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NetB	NP_001162753.1	LamNT	37..261	CDD:214532	63/231 (27%)
		EGF_Lam	<458..484	CDD:238012	13/25 (52%)
		EGF_Lam	498..555	CDD:238012	19/56 (34%)
		EGF_Lam	560..608	CDD:238012	18/38 (47%)
		NTR_netrin-1_like	661..791	CDD:239634
Ntng1	XP_006502418.1	Laminin_N	71..295	CDD:365840	75/373 (20%)
		EGF_Lam	296..342	CDD:238012	24/83 (29%)
		EGF_Lam	406..454	CDD:238012	19/54 (35%)
		EGF_Lam	462..509	CDD:214543	18/37 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3512
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810