Protein Alignment NetB and LOC1272041

DIOPT Version :10

• Sequence 1: NP_511155.1
• Gene: NetB / 32400
• FlyBaseID: FBgn0015774
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: XP_061513445.1
• Gene: LOC1272041 / 1272041
• VectorBaseID: AGAMI1_005731
• Length: 761
• Species: Anopheles gambiae
• Alignment Length: 854
• Identity: 388/854 - (45%)
• Similarity: 504/854 - (59%)
• Gaps: 180/854 - (21%)

  Fly     9 MGLLLPIILALAIGSSAAGI--SSNDPCYFEGKPRKCLPSFVNAAYGNPVQASSVCGAQQPERYC 71
            :.||..:::|||..::.|..  :|.||||.|.:||:|||.|||||.|.||.|||.||.:..:|.|
Mosquito    17 LALLALVVVALAPAAARAASLDASYDPCYDEDRPRRCLPDFVNAALGMPVVASSTCGQRGLDRLC 81

  Fly    72 ELLRDGNAGECRSCE----QQRYGPAALTDLNNPSNVTCWRSGAVNVPHDPDSAPPDNVTLTLSL 132
            ::.:......|..|:    ::||.|.||||:||.:|||||||..:..|...:. |||||||||||
Mosquito    82 DVQQPVQRPRCLPCDDGNPRKRYPPTALTDVNNSNNVTCWRSEPLRSPASIND-PPDNVTLTLSL 145

  Fly   133 GKKYELTYISLSFCPRSPRPDSLAIFKSSDFGQTWQPFQFYSSQCQKFYGRPDRAKISKFNEQEA 197
            |||||||||||:|||.:.:|||:||:||:|.|::|||||||||||::.||||:||.|::.|||||
Mosquito   146 GKKYELTYISLTFCPGTVKPDSIAIYKSADHGKSWQPFQFYSSQCRRVYGRPNRATITRANEQEA 210

  Fly   198 RCINS-QHDTGGA--AQRFAFNTLEGRPSANDLDSSLVLQDWVTATDIRVVFHRLELPPQLLKVK 259
            ||.:: :|....|  ..|.||:||||||||.|.|||.||||||||||:|:||||.::||.
Mosquito   211 RCTDAHRHGLAEAPTVSRIAFSTLEGRPSAPDFDSSPVLQDWVTATDVRIVFHRHQMPPD----- 270

  Fly   260 NANAFSDEMGGSREEDEDDDADLELDGEQDEYDYNLQDNDSADAGYDEYEEPKKHLELDDDHLHL 324
                                                          |.:|:|          .:|
Mosquito   271 ----------------------------------------------DTFEDP----------WYL 279

  Fly   325 DYAS---DGESVVKRQGKHKGSAYEKHYQSKLAATTPPQQPPKVTPPGKVTPPSTAAPSAAASAV 386
            .::|   .|.:..:||.:...:.:...:..:..:|||..|..:..||  ..||..||..:.::|.
Mosquito   280 RHSSAQVPGSAAFRRQPRDLPADFATDWPEQAGSTTPDYQSEEAAPP--PPPPPPAATRSQSNAA 342

  Fly   387 TLPIS--------------------QHYAVSDFAVGGRCKCNGHASECVATVSSGSGTALSDQDD 431
            ..|.|                    .|||||||||||||||||||..||
Mosquito   343 EQPASTIKPPAEVLGNHGRARQPPHHHYAVSDFAVGGRCKCNGHAFRCV---------------- 391

  Fly   432 GQDEDTPSAPSLANHFGRSTQMSAKLTMTCACKHNTAGPECERCKPFYFDRPWGRATDNDANECK 496
                  |:.|.     |.         ::|.|||||||.:|||||||:||||||||...||||||
Mosquito   392 ------PAGPD-----GE---------VSCDCKHNTAGRDCERCKPFHFDRPWGRANARDANECK 436

  Fly   497 MCQCNGHARRCRFNLELYKLSGRVSGGVCYNCQHDTTGRYCHYCREGYYRDATKPPNHRKVCKRC 561
            .|.|||||||||||:||||:|||:|||||.:|:|.||||:|||||||:|||||||..||||||.|
Mosquito   437 ACNCNGHARRCRFNMELYKMSGRISGGVCLSCRHATTGRHCHYCREGFYRDATKPITHRKVCKAC 501

  Fly   562 DCHPVGSTGKTCNHLSGQCPCKEGVTGLTCNRCARGYQQTRSHVAPCIKVPTNANMIQAES---- 622
            ||||:||:||||||.:||||||:||||||||||||||||:|||:|||||:|...||:.:::
Mosquito   502 DCHPIGSSGKTCNHTTGQCPCKDGVTGLTCNRCARGYQQSRSHIAPCIKIPRVINMVHSQNTAPE 566

  Fly   623 -----AGGGGGGGTGD-----YKDGGGSQVEEMKKYCGKCKASPKKLNLNKFCMEDYAILAKVIG 677
                 |...||||..:     |:...|.:       |||||.|.|:|||||||..||||:|||||
Mosquito   567 ESHQYAVSSGGGGQHEPEAPTYRMHAGRE-------CGKCKISTKRLNLNKFCKRDYAIMAKVIG 624

  Fly   678 HDRASQDISTEKFSIERQNEIYKYE-------------------INIQTIFKRNPMSGTTSSLLG 723
            .|....|..|.|.|....|....|:                   :::|.:|||   |.:.:|.|.
Mosquito   625 KDTKPSDSGTGKGSTGSGNPSQPYQPPPPRYRGTPPEDGAVRFHLSVQKVFKR---SRSPASPLA 686

  Fly   724 R----GNMMLLVPRKSIECQCPKIKLNKSYLILGRDSEAAPGYLAIGPSSVVLEWKDEWSLRMKR 784
            :    .::..:|....::|:|||:|:::||||||.:||...|.|.:||.::::||:|||..|:::
Mosquito   687 KASKWSDVPYIVSAHDLDCRCPKLKVHRSYLILGNESEGPAGTLGVGPRTILIEWRDEWHRRLRK 751

  Fly   785 FQRRA-RKC 792
            |||:| |.|
Mosquito   752 FQRQADRTC 760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NetB	NP_511155.1	LamNT	37..261	CDD:214532	133/230 (58%)
		EGF_Lam	<458..484	CDD:238012	18/25 (72%)
		EGF_Lam	498..555	CDD:238012	44/56 (79%)
		EGF_Lam	560..608	CDD:238012	39/47 (83%)
		NTR_netrin-1_like	661..791	CDD:239634	56/153 (37%)
LOC1272041	XP_061513445.1	None