DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5321 and bbox1

DIOPT Version :9

Sequence 1:	NP_001285244.1	Gene:	CG5321 / 32399	FlyBaseID:	FBgn0030575	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	XP_005168960.1	Gene:	bbox1 / 572649	ZFINID:	ZDB-GENE-050417-218	Length:	433	Species:	Danio rerio

Alignment Length:	410	Identity:	158/410 - (38%)
Similarity:	227/410 - (55%)	Gaps:	19/410 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PRLLGRSL--SQLKTINSAQFSRQISAKIVNESSIEVQPEANSKPLTFPGIWLRDNCMCEDCFHG 66
            ||:..::|  :.|.....:...||..| :..|..:::..:..|..| :|..||||||.|..|...
Zfish    30 PRIGNQTLAAAPLPFAGGSPGVRQARA-LDQERLLQIDWDDGSCSL-YPFTWLRDNCQCPLCTLQ 92

  Fly    67 SSKSRKLDWDNFD--TRIRPVSLQTDEQSKEVLVKWSDAHESRFSLKWLKERCFEPDKQQEYLRD 129
            |:::|.|.:.:.|  |.:..|.|    ...:|.:.|.|.|.|.|...|||:|||..:.:|....:
Zfish    93 SAQARSLLFSHLDVHTGMDHVQL----MDNKVSITWPDQHSSEFDPDWLKKRCFSSEARQALQEE 153

  Fly   130 FYRPTTRHW-SGAEFQDIAQHFSYDEVMSQDSVLMQWLQALAIYGVALLRGAPLDEGVVRRLADR 193
            .:.....:| ||.:....    .::||:..|...:.||:||...|:..|||||.::|.:.||:.|
Zfish   154 LFLNEREYWDSGLQIPTA----DFEEVLHDDKAALAWLEALRRIGIVYLRGAPAEQGQLARLSQR 214

  Fly   194 VGFIRRTTYGEEFVVQAKPGAQNFAYLSLTLPLHTDLPYYEYKPSVNILHCVVQTDSPGGSNMLV 258
            :|::|.|.||..:.||.||.|.|.||.|..|.||||.|...:.|.|..||||.|.|. ||.:.:|
Zfish   215 IGYLRLTFYGHTWQVQDKPMANNVAYTSGELSLHTDYPALHHPPGVQFLHCVRQADE-GGESEVV 278

  Fly   259 DGFHVADLLRRDHPEDFERLSRIVVDWNDIGSEDGREFHNIWRAPVICLDEEGRYTRINHSVPQR 323
            ||||:|:.|||:.||.|..||.:.||:.|.|: |..:|....:..:|.:|..||..|||::...|
Zfish   279 DGFHMAEQLRREDPEAFNILSSLRVDFTDSGA-DYCDFSVQSKNHIIDVDSSGRVVRINYNNATR 342

  Fly   324 DSHFNVPLEEVLPWYESYALFVRLAIADSHAFKTR--PGDVLTFNNIRLLHGRTGYDDSEESPRY 386
            ||..::||.:|.|:|.|...||.|.....:.|..|  ||||:||:|.||||||..|....::.|:
Zfish   343 DSVLDLPLHQVQPFYSSLKAFVELLSRPENVFTYRMEPGDVVTFDNWRLLHGRKSYQSRGQNLRH 407

  Fly   387 IVGAYLDWDIIYSRLRVLKK 406
            :.|||||||.:.||||:|:|
Zfish   408 LEGAYLDWDEVMSRLRILRK 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5321	NP_001285244.1	DUF971	<48..113	CDD:294847	22/66 (33%)
		carnitine_bodg	49..405	CDD:274118	146/360 (41%)
		CAS_like	127..395	CDD:238154	111/270 (41%)
bbox1	XP_005168960.1	TauD	62..426	CDD:331497	148/374 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587911
Domainoid	1	1.000	195	1.000	Domainoid score	I3098
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2967
Inparanoid	1	1.050	265	1.000	Inparanoid score	I3037
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D534559at33208
OrthoFinder	1	1.000	-	-		FOG0003526
OrthoInspector	1	1.000	-	-		otm26624
orthoMCL	1	0.900	-	-		OOG6_102379
Panther	1	1.100	-	-	LDO	PTHR10696
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2892
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.900