DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5321 and CG10814

DIOPT Version :9

Sequence 1:	NP_001285244.1	Gene:	CG5321 / 32399	FlyBaseID:	FBgn0030575	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_610868.1	Gene:	CG10814 / 36481	FlyBaseID:	FBgn0033830	Length:	402	Species:	Drosophila melanogaster

Alignment Length:	375	Identity:	205/375 - (54%)
Similarity:	275/375 - (73%)	Gaps:	1/375 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 NESSIEVQPEANSKPLTFPGIWLRDNCMCEDCFHGSSKSRKLD-WDNFDTRIRPVSLQTDEQSKE 95
            ::|.:...|:.:.:.:.||.|||||||.||:|:...:.||... |::.||.:|.:....|...:.
  Fly    23 DQSRLVQVPDPDRRDMQFPDIWLRDNCRCEECYLPQTLSRLPQLWNHLDTSVRVLRQSVDVDQRV 87

  Fly    96 VLVKWSDAHESRFSLKWLKERCFEPDKQQEYLRDFYRPTTRHWSGAEFQDIAQHFSYDEVMSQDS 160
            :.::|||.|.|::...||:||.|....:|.||||||||..:.|||.:|:.|.|.|.|.|::..||
  Fly    88 LCIEWSDGHTSQYPFSWLRERDFSYANRQRYLRDFYRPEQKLWSGLDFEKIRQVFYYQELLDCDS 152

  Fly   161 VLMQWLQALAIYGVALLRGAPLDEGVVRRLADRVGFIRRTTYGEEFVVQAKPGAQNFAYLSLTLP 225
            .|.||||.||:||||:::.||||..|:|||::||||:|||||||||.|:|:||..|:|||:..||
  Fly   153 ALQQWLQHLAVYGVAMVKEAPLDMDVLRRLSNRVGFMRRTTYGEEFSVRAQPGGSNYAYLAAPLP 217

  Fly   226 LHTDLPYYEYKPSVNILHCVVQTDSPGGSNMLVDGFHVADLLRRDHPEDFERLSRIVVDWNDIGS 290
            ||||:||:||.|.|.:||.:.|:.||||.|:|.|.|:||:::|..:||.|..|.:..|||.||||
  Fly   218 LHTDMPYFEYLPGVTMLHTLEQSASPGGVNLLADAFYVAEVMRERYPEQFRVLCQTPVDWADIGS 282

  Fly   291 EDGREFHNIWRAPVICLDEEGRYTRINHSVPQRDSHFNVPLEEVLPWYESYALFVRLAIADSHAF 355
            :...:||||||||||.||.|||..|||||:|||||||:||:|:|.||||:.|.||.||...|..|
  Fly   283 DGDLQFHNIWRAPVINLDAEGRCVRINHSIPQRDSHFSVPVEQVRPWYEAMATFVGLAHEHSCRF 347

  Fly   356 KTRPGDVLTFNNIRLLHGRTGYDDSEESPRYIVGAYLDWDIIYSRLRVLK 405
            ||.|||||||:|:||:||||||||::.:.|:|:||::||||:|||||||:
  Fly   348 KTTPGDVLTFDNLRLVHGRTGYDDTDRNVRHILGAFVDWDIVYSRLRVLR 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5321	NP_001285244.1	DUF971	<48..113	CDD:294847	24/65 (37%)
		carnitine_bodg	49..405	CDD:274118	202/356 (57%)
		CAS_like	127..395	CDD:238154	162/267 (61%)
CG10814	NP_610868.1	DUF971	22..106	CDD:283749	27/82 (33%)
		carnitine_bodg	27..398	CDD:274118	204/371 (55%)
		CAS_like	119..387	CDD:238154	162/267 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457818
Domainoid	1	1.000	195	1.000	Domainoid score	I3098
eggNOG	1	0.900	-	-		E1_COG2175
Homologene	1	1.000	-	-		H2967
Inparanoid	1	1.050	265	1.000	Inparanoid score	I3037
Isobase	1	0.950	-	0.909372	Normalized mean entropy	S3503
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D49489at7147
OrthoFinder	1	1.000	-	-		FOG0003526
OrthoInspector	1	1.000	-	-		otm26624
orthoMCL	1	0.900	-	-		OOG6_102379
Panther	1	1.100	-	-	P	PTHR10696
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2892
	13	12.750