DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5321 and bbox1

DIOPT Version :9

Sequence 1:	NP_001285244.1	Gene:	CG5321 / 32399	FlyBaseID:	FBgn0030575	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001120574.1	Gene:	bbox1 / 100145728	XenbaseID:	XB-GENE-956892	Length:	442	Species:	Xenopus tropicalis

Alignment Length:	418	Identity:	161/418 - (38%)
Similarity:	233/418 - (55%)	Gaps:	25/418 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LGRSLSQL-KTINSAQF-SRQISAK----IVNESSIE------VQPEANSKPLTFPGIWLRDNCM 59
            |.|||.|. :..:||:| :.::.|.    |.|..|:|      |..|...:.: :|.:||||||.
Frog    30 LSRSLLQFTRWQHSARFLAEELPASPLVMIRNVESLEKERFVCVHWEDGGQSV-YPFVWLRDNCQ 93

  Fly    60 CEDCFHGSSKSRKLDWDNFD--TRIRPVSLQTDEQSKEVLVKWSDAHESRFSLKWLKERCFEPDK 122
            |..||..|:|:|||..::.|  |.::.|:|   ..||:|.:.|.|.|:|.|..:|||:|||....
Frog    94 CPQCFLHSAKARKLPIEDLDVNTGVKDVTL---TNSKKVSITWPDEHQSEFDGEWLKKRCFSKHA 155

  Fly   123 QQEYLRDFYRPTTRHWSGAEFQDIAQHFSYDEVMSQDSVLMQWLQALAIYGVALLRGAPLDEGVV 187
            :.|...:.:....::| |::.|  ....||::|::.|....|||.||...|:.||.|||:.:|.:
Frog   156 RAEMQDELFASEHQYW-GSDLQ--IPTMSYEDVLNCDQTAYQWLCALRKVGIVLLEGAPVKQGEL 217

  Fly   188 RRLADRVGFIRRTTYGEEFVVQAKPGAQNFAYLSLTLPLHTDLPYYEYKPSVNILHCVVQTDSPG 252
            ..|..|:|::|.|.||..:.||.|..|.|.||.:..|.||||.|..:|.|.|..|||:.|..| |
Frog   218 LSLGKRIGYMRLTFYGYTWQVQDKADANNVAYTAGKLSLHTDYPALQYPPGVQFLHCLKQAQS-G 281

  Fly   253 GSNMLVDGFHVADLLRRDHPEDFERLSRIVVDWNDIGSEDGREFHNIWRAPVICLDEEGRYTRIN 317
            |.:.:||||||...||..:||.|..|:...:|:.|.| .|..:|....:..:|.||.:|...|||
Frog   282 GESEVVDGFHVCRKLREQNPEAFNILTSAQIDFTDTG-VDYCDFALQSKQRIIELDPKGNLLRIN 345

  Fly   318 HSVPQRDSHFNVPLEEVLPWYESYALFVRLAIADSHAF--KTRPGDVLTFNNIRLLHGRTGYDDS 380
            .:...|||..::|.:.|.|:|.|...||.|.....:.|  |.:||.|:||:|.|:||||..|...
Frog   346 FNNATRDSVLDIPADRVQPFYSSLRAFVDLMNRPENTFSYKMQPGHVVTFDNWRILHGRRSYQSE 410

  Fly   381 EESPRYIVGAYLDWDIIYSRLRVLKKRL 408
            ....|::.|:|||||::.||:|.|||:|
Frog   411 ATVSRHLEGSYLDWDVVLSRMRSLKKKL 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5321	NP_001285244.1	DUF971	<48..113	CDD:294847	27/66 (41%)
		carnitine_bodg	49..405	CDD:274118	142/359 (40%)
		CAS_like	127..395	CDD:238154	103/269 (38%)
bbox1	NP_001120574.1	DUF971	66..146	CDD:283749	30/83 (36%)
		carnitine_bodg	71..435	CDD:274118	144/372 (39%)
		CAS_like	162..425	CDD:238154	103/267 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	169	1.000	Domainoid score	I3755
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2967
Inparanoid	1	1.050	260	1.000	Inparanoid score	I3028
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D534559at33208
OrthoFinder	1	1.000	-	-		FOG0003526
OrthoInspector	1	1.000	-	-		otm48762
Panther	1	1.100	-	-	LDO	PTHR10696
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2023
SonicParanoid	1	1.000	-	-		X2892
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.100