Protein Alignment NetA and ntng1a

DIOPT Version :9

• Sequence 1: NP_001285243.1
• Gene: NetA / 32398
• FlyBaseID: FBgn0015773
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: XP_009295804.2
• Gene: ntng1a / 569075
• ZFINID: ZDB-GENE-091118-13
• Length: 545
• Species: Danio rerio
• Alignment Length: 539
• Identity: 163/539 - (30%)
• Similarity: 235/539 - (43%)
• Gaps: 125/539 - (23%)

  Fly    41 YNKAHEPRAC-IPDFVNAAYDAPVVASSTCGSSGAQRYCEYQDHERSCHTCD-MTDPLRSFPARS 103
            |..|.:|.|. :..::....|.|.:   |||.. .:.||..::.....:.|| .||.| :.|...
Zfish    46 YYMACQPEAADMTKYLKVTLDPPNI---TCGDP-PETYCTLENPYMCNNECDAATDEL-AHPPEL 105

  Fly   104 LTDLNNSNNVTCWRS-------EPVTGSGDNVTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYK 161
            :.|:...|..|.|:|       :|:.     |.:|||..|..|||..|: :...:.||:.||:.|
Zfish   106 MFDIVGRNPTTFWQSTSWKKYPKPLA-----VNITLSWNKTIELTDDIV-ITFESGRPEQMVLEK 164

  Fly   162 STDHGLSWQPFQFFSSQCRRLFGRPAR--QSTGRHNEHEARC-----------SDVTRPLVSRIA 213
            |.|:|.||||:||:::.|...|....:  :...:|...:..|           :|.|.....|..
Zfish   165 SLDYGRSWQPYQFYATDCLDAFTMEPKTMKDITQHTLLDIICTEEYSRGYVWKNDKTVRFEIRDR 229

  Fly   214 FSTLEGRPSSRD-------LDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGK 271
            |:...| |...:       ||::..|:|:.|.||:|:   ||.||         |.|||.:..
Zfish   230 FALFAG-PKLHNMASLYGQLDTTKNLRDFFTITDLRI---RLLRP---------ATGATMVDE-- 279

  Fly   272 YSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSH 336
                       ||:            |..:|||||..|.||||||.||:.|..|.. :|.|||.|
Zfish   280 -----------NNL------------SRYYYAISDIKVHGRCKCNLHANSCIYDKE-KLTCECEH 320

  Fly   337 NTAGRDCERCKPFHFDRPWARAT-----AKEANECK-------ECNCNKHARQCRFNMEIFRLSQ 389
            ||.|.||.|||.....|.|:..:     ...||.|.       .|.|..|:.:|.: :|:
Zfish   321 NTTGPDCGRCKRNFQARAWSAGSYLPIPKGTANICMANYAGPVNCECYNHSNRCSY-IEV----- 379

  Fly   390 GVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVCKACDCHPIGSSGKICNSTSGQCPCK 454
             ::..:|.:|:|:|.|::||.||.|:||:||.......:|..|:|:|.||....||.| |.|.||
Zfish   380 -LNAVICVSCKHNTRGQHCHLCKLGYYRNATAKPDDENICIDCNCNPFGSESDRCNGT-GYCRCK 442

  Fly   455 DGVTGLTCNRCARGYQ-----QSR---SHIAPC-----------IKQPPRMINMLDTQNTAPEPD 500
            :|.||..|:.|..||.     :||   |.:..|           .:.||....:|      .|..
Zfish   443 EGATGAMCHECLPGYLWDNGCKSRVCDSELLRCQNGGVCVNYVRCQCPPAYTGLL------CEKP 501

  Fly   501 EPESSPGS-GGDRNGAAGM 518
            ..|..||. ||..:|.|.:
Zfish   502 RCEKEPGGCGGSDSGQASL 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NetA	NP_001285243.1	LamNT	44..280	CDD:214532	71/264 (27%)
		EGF_Lam	312..357	CDD:238012	24/44 (55%)
		EGF_Lam	369..426	CDD:238012	19/56 (34%)
		EGF_Lam	431..479	CDD:238012	22/55 (40%)
		NTR_netrin-1_like	545..723	CDD:239634
ntng1a	XP_009295804.2	Laminin_N	69..296	CDD:306548	75/275 (27%)
		EGF_Lam	297..343	CDD:238012	24/46 (52%)
		EGF_Lam	355..413	CDD:238012	20/64 (31%)
		EGF_Lam	421..468	CDD:238012	21/47 (45%)
		EGF_CA	<475..499	CDD:238011	4/29 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910