Protein Alignment NetA and Ntng2

DIOPT Version :9

• Sequence 1: NP_001285243.1
• Gene: NetA / 32398
• FlyBaseID: FBgn0015773
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: XP_006233862.1
• Gene: Ntng2 / 311836
• RGDID: 1307089
• Length: 635
• Species: Rattus norvegicus
• Alignment Length: 567
• Identity: 139/567 - (24%)
• Similarity: 204/567 - (35%)
• Gaps: 207/567 - (36%)

  Fly    49 ACIP------DFVNAAYDAPVVASSTCGSSGAQRYCEYQDHERSCHTCDMTDPLRSFPARSLTDL 107
            ||.|      |:|....:.   :..|||.. .:|:|.:::.....:.||.::|..:.|.|.:.|.
  Rat    38 ACQPKVMRLKDYVKVKVEP---SGITCGDP-PERFCSHENPYLCSNECDASNPDLAHPPRLMFDR 98

  Fly   108 NNSNNVTCWRSEPVTGSGD----NVTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLS 168
            .:....|.|:|  ||.|..    ...:|||..|..|||..::....:. ||..||:.||.|:|.:
  Rat    99 EDEGLATYWQS--VTWSRYPSPLEANITLSWNKSVELTDDVVMTFEYG-RPTVMVLEKSLDNGRT 160

  Fly   169 WQPFQFFSSQCRRLFGRPARQS--TGRHNEHEARCSDVTRPLVSRIAFSTLE------------- 218
            |||:||::..|...||..||::  ....:.|...|::.    .||.|.|..|
  Rat   161 WQPYQFYAEDCMEAFGMSARRARDMSPSSAHRVLCTEE----YSRWAGSKKEKHVRFEVRDRFAI 221

  Fly   219 -GRPSSRDLD-------SSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVP 275
             ..|..|::|       |:..|:::.|.||:|:   ||.||   ||     ||........|.
  Rat   222 FAGPDLRNMDNLYTRMESAKGLKEFFTFTDLRM---RLLRP---AL-----GGTYVQRENLYK-- 273

  Fly   276 LANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAG 340
                                    ..||||:..|.||||||.||:.| |...|.|.|||.|||.|
  Rat   274 ------------------------YFYAISNIEVIGRCKCNLHANLC-TVREGSLQCECEHNTTG 313

  Fly   341 RDCERCKPFHFDRPW----------------------------------------ARAT------ 359
            .||.:||.....|.|                                        ..||
  Rat   314 PDCGKCKKNFRTRAWRAGSYLPLPHGSPNACAAAGSAFGSTSRSRKIPAPKAPMATEATRRGPVT 378

  Fly   360 --------------------------------------------------------AKEA----- 363
                                                                    ||::
  Rat   379 SIPSTSTIQVPTAPSTPHPTGQTKPTTVAPLGDSSFWPQVSSSAEAVTIPVAIPSQAKDSTLFQL 443

  Fly   364 ----------NECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRD 418
                      .|.::|.|..|:.:|.: ::...:.      .|.:|:|:|.|::|..|:.|:||:
  Rat   444 KPRSPQVIPIEEFQDCECYGHSNRCSY-IDFLNVV------TCVSCKHNTRGQHCQHCRLGYYRN 501

  Fly   419 ATKPLTHRKVCKACDCHPIGSSGKICNSTSGQCPCKDGVTGLTCNRC 465
            .:..|....||..|:|:.|||....||.| |.|.|::|..|..|:.|
  Rat   502 GSAELDDENVCIECNCNQIGSVHDRCNET-GFCECREGAVGPKCDDC 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NetA	NP_001285243.1	LamNT	44..280	CDD:214532	72/263 (27%)
		EGF_Lam	312..357	CDD:238012	24/84 (29%)
		EGF_Lam	369..426	CDD:238012	15/56 (27%)
		EGF_Lam	431..479	CDD:238012	15/35 (43%)
		NTR_netrin-1_like	545..723	CDD:239634
Ntng2	XP_006233862.1	Laminin_N	60..285	CDD:278484	72/269 (27%)
		EGF_Lam	286..332	CDD:238012	24/46 (52%)
		EGF_Lam	459..507	CDD:238012	14/54 (26%)
		Laminin_EGF	515..562	CDD:278482	15/34 (44%)
		EGF_2	562..592	CDD:285248

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3512
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810