DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NetA and Ushbp1

DIOPT Version :9

Sequence 1:	NP_001285243.1	Gene:	NetA / 32398	FlyBaseID:	FBgn0015773	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_001028859.1	Gene:	Ushbp1 / 290629	RGDID:	1310859	Length:	680	Species:	Rattus norvegicus

Alignment Length:	209	Identity:	40/209 - (19%)
Similarity:	62/209 - (29%)	Gaps:	76/209 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   490 LDTQNTAPEPDEPESSPGSGGDRNGAAG-----------MAAQSQYYRTEGGR------ECGKCR 537
            |.||..:||....|...|.      ..|           :.|..|.|:   ||      :.||..
  Rat   270 LSTQRPSPEMYLMEDQMGQ------LQGNIEKLKCFNRLLLAVLQGYK---GRCESLSIKLGKRE 325

  Fly   538 VSTKRLNL----NKFCKRDYAIM---------AKVIGRDTSSEAVSREVQRRAMDPDVADYEMDQ 589
            .....|:|    :|.|:..|.::         |.|...:...:|..:|..|..:..:|
  Rat   326 AEATALHLALQYSKDCEEVYEVLLALKTAGLGAGVGATNGDLQAAEKEASRLLVKKEV------- 383

  Fly   590 VQPGSARSPITGVYEFQAADYPNPNPNPRGSEMERFDLQIQAVFKRSRPGESSGAGNVYGMPNTT 654
                             |.|...|.|:|.||.::             :|.....|..::|.....
  Rat   384 -----------------AMDVKTPQPSPEGSSVD-------------KPTPEELAAQLHGYVQHL 418

  Fly   655 LKRGPMTWIIPTKD 668
            .:|..:..|.|..|
  Rat   419 RERWALLKIPPVLD 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NetA	NP_001285243.1	LamNT	44..280	CDD:214532
		EGF_Lam	312..357	CDD:238012
		EGF_Lam	369..426	CDD:238012
		EGF_Lam	431..479	CDD:238012
		NTR_netrin-1_like	545..723	CDD:239634	24/137 (18%)
Ushbp1	NP_001028859.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..101
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	135..162
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	217..250
		MCC-bdg_PDZ	288..352	CDD:287477	13/72 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	524..562
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3512
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900